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Your search keyword '"Liu, Yan"' showing total 2 results
Start Over Author "Liu, Yan" Topic 8-hydroxyquinoline
2 results on '"Liu, Yan"'

1. Synthesis and application of 8-hydroxyquinoline modified magnetic mesoporous carbon for adsorption of multivariate metal ions from aqueous solutions.

Author

Guo, Wenlu, Meng, Xiangguo, Liu, Yan, Ni, Liang, Hu, Zhaoyong, Chen, Rui, Meng, Minjia, Wang, Yun, Han, Juan, and Luo, Min

Subjects
CHEMICAL synthesis, HYDROXYQUINOLINE, MESOPOROUS materials, MAGNETIC properties, CARBON compound analysis, ADSORPTION (Chemistry), AQUEOUS solutions
Abstract

The new 8-hydroxyquinoline (8-HQ) modified magnetic mesoporous carbon (8-HQ-Ni-CMK-3) was prepared and applied for adsorption of multivariate metal ions from aqueous solution. The prepared adsorbent was characterized by Fourier transform infrared, X-ray diffraction, scanning electron microscopy, transmission electron microscope, nitrogen adsorption-desorption isotherm, elemental analysis, and vibrating sample magnetometer. The static adsorption behaviors toward multivariate metal ions on graphite, the modified graphite by 8-HQ, magnetic mesoporous carbon, and 8-HQ-Ni-CMK-3 were compared, which showed that 8-HQ-Ni-CMK-3 had excellent adsorption capacity. The removal of multivariate metal ions using 8-HQ-Ni-CMK-3 by fixed-bed column was further investigated. [ABSTRACT FROM AUTHOR]

Published
2015
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2. Studies on antitumor mechanism of two planar platinum(II) complexes with 8-hydroxyquinoline: Synthesis, characterization, cytotoxicity, cell cycle and apoptosis.

Author

Qin, Qi-Pin, Chen, Zhen-Feng, Qin, Jiao-Lan, He, Xiao-Ju, Li, Yu-Lan, Liu, Yan-Cheng, Huang, Ke-Bin, and Liang, Hong

Subjects
*ANTINEOPLASTIC agents, *HYDROXYQUINOLINE, *APOPTOSIS, *CELL-mediated cytotoxicity, *CELL cycle, *MITOCHONDRIAL membranes
Abstract

[Pt(Q) 2 ] ( 1 ) and [Pt(MQ) 2 ] ( 2 ) exhibited enhanced cytotoxicity against BEL-7404, Hep-G2, NCI–H460, T-24, A549 tumor cells but low cytotoxicity on normal HL-7702 cells. 1 and 2 could cause the cell cycle arrest in G2 and S phase, respectively. While pifithrin-α, a specific p53 inhibitor, induced cell cycle arrest in G1 phase. Although 1 , 2 and pifithrin-α caused serious inhibition on p53, 1 and 2 significantly cause the loss of mitochondrial membrane potential and increase of the reactive oxygen species level, cytochrome c , apaf-1 and caspase-3/9 ratio in BEL-7404 cells. 1 and 2 may trigger the cell apoptosis through a mitochondrial dysfunction pathway whereas pifithrin-α does not. The interactions of 1 and 2 with DNA are most probably via an intercalation. [ABSTRACT FROM AUTHOR]

Published
2015
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