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Your search keyword '"Maciaczyk D"' showing total 3 results
Start Over Author "Maciaczyk D" Topic 610 medical sciences
3 results on '"Maciaczyk D"'

1. Resistance to hypoxia-induced, BNIP3-mediated cell death contributes to the increase of CD133+ cell population in human glioblastoma-derived cultures in lowered oxygen tension

Author

Kahlert, U., Maciaczyk, D., Döbrössy, M., Herold-Mende, C.H., Nikkhah, G., and Maciaczyk, J.

Subjects
Hirntumorstammzellen, Hypoxie, ddc: 610, hypoxia, Apoptose, apoptosis, 610 Medical sciences, Medicine, brain tumor stem cells
Abstract

Objective: Brain tumor stem-like cells (BTSC) are responsible for tumor initiation, propagation and resistance to standard therapies. Previous reports showed hypoxia-induced increase of BTSC expressing CD133 together with over-expression of other stem cell-related genes and more pronounced clonogenic[for full text, please go to the a.m. URL], 63. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie (JNS)

Published
2012

2. The role of canonical WNT/beta-catenin signaling in glial brain tumors

Author

Maciaczyk, J., Kahlert, U., Maciaczyk, D., Simons, B., Orr, B., Eberhart, C., and Nikkhah, G.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Objective: The canonical WNT/β-catenin pathway plays an important role in embryo- and carcinogenesis. Although β-catenin has been abnormally expressed in a variety of human cancers, little is known about its involvement in the biology of glial tumors. In this project the role of WNT/β-catenin[for full text, please go to the a.m. URL], 62. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgen (PNCH)

Published
2011

3. The influence of in vitro conditions for the enrichment of stem-like cell population in primary human brain tumor cultures

Author

Kahlert, UD, Maciaczyk, D, Nikkhah, G, and Maciaczyk, J

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Objective: Recently demonstrated slowly proliferating stem-like cell population (BTSC) in malignant brain tumors, responsible for tumor initiation and propagation, allowed the identification of the molecular mechanisms underlying their resistance to both chemo- and radiotherapy. Reduction of BTSC population[for full text, please go to the a.m. URL], 60. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit den Benelux-Ländern und Bulgarien

Published
2009
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