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Your search keyword '"Muhairwe, Josephine"' showing total 12 results
Start Over Author "Muhairwe, Josephine" Topic 3. good health
12 results on '"Muhairwe, Josephine"'

1. Additional file 1: of VIBRA trial â Effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho

Author

Amstutz, Alain, Thabo Lejone, Lefu Khesa, Muhairwe, Josephine, Bienvenu Nsakala, Katleho Tlali, Bresser, Moniek, Tediosi, Fabrizio, Mathebe Kopo, Mpho Kao, Klimkait, Thomas, Battegay, Manuel, Glass, Tracy, and Labhardt, Niklaus

Subjects
3. Good health
Abstract

GET ON electronic case report form. (PDF 1050 kb)

2. The HOSENG trial - effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage : protocol of a cluster-randomized clinical trial in rural Lesotho

Author

Amstutz, Alain, Lejone, Thabo Ishmael, Khesa, Lefu, Muhairwe, Josephine, Nsakala, Bienvenu Lengo, Tlali, Katleho, Bresser, Moniek, Vanobberghen, Fiona, Kopo, Mathebe, Kao, Mpho, Klimkait, Thomas, Battegay, Manuel, Labhardt, Niklaus Daniel, and Glass, Tracy Renée

Subjects
1. No poverty, 3. Good health

4. Additional file 2: of VIBRA trial â Effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho

Author

Amstutz, Alain, Thabo Lejone, Lefu Khesa, Muhairwe, Josephine, Bienvenu Nsakala, Katleho Tlali, Bresser, Moniek, Tediosi, Fabrizio, Mathebe Kopo, Mpho Kao, Klimkait, Thomas, Battegay, Manuel, Glass, Tracy, and Labhardt, Niklaus

Subjects
3. Good health
Abstract

SPIRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents. (PDF 82 kb)

6. Additional file 1: of VIBRA trial â Effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho

Author

Amstutz, Alain, Thabo Lejone, Lefu Khesa, Muhairwe, Josephine, Bienvenu Nsakala, Katleho Tlali, Bresser, Moniek, Tediosi, Fabrizio, Mathebe Kopo, Mpho Kao, Klimkait, Thomas, Battegay, Manuel, Glass, Tracy, and Labhardt, Niklaus

Subjects
3. Good health
Abstract

GET ON electronic case report form. (PDF 1050 kb)

7. Additional file 1: of The HOSENG trial â Effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage: protocol of a cluster-randomized clinical trial in rural Lesotho

Author

Amstutz, Alain, Thabo Lejone, Lefu Khesa, Muhairwe, Josephine, Bienvenu Nsakala, Katleho Tlali, Bresser, Moniek, Vanobberghen, Fiona, Mathebe Kopo, Mpho Kao, Klimkait, Thomas, Battegay, Manuel, Labhardt, Niklaus, and Glass, Tracy

Subjects
behavioral disciplines and activities, 3. Good health
Abstract

Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 Checklist: recommended items to address in a clinical trial protocol and related documents*. (PDF 82 kb)

8. Additional file 2: of VIBRA trial â Effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho

Author

Amstutz, Alain, Thabo Lejone, Lefu Khesa, Muhairwe, Josephine, Bienvenu Nsakala, Katleho Tlali, Bresser, Moniek, Tediosi, Fabrizio, Mathebe Kopo, Mpho Kao, Klimkait, Thomas, Battegay, Manuel, Glass, Tracy, and Labhardt, Niklaus

Subjects
3. Good health
Abstract

SPIRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents. (PDF 82 kb)

9. VIBRA trial - Effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV : protocol of a cluster-randomized clinical trial in rural Lesotho

Author

Amstutz, Alain, Lejone, Thabo Ishmael, Khesa, Lefu, Muhairwe, Josephine, Nsakala, Bienvenu Lengo, Tlali, Katleho, Bresser, Moniek, Tediosi, Fabrizio, Kopo, Mathebe, Kao, Mpho, Klimkait, Thomas, Battegay, Manuel, Glass, Tracy Renée, and Labhardt, Niklaus Daniel

Subjects
3. Good health

10. Trends in CD4 and viral load testing 2005 to 2018: multi-cohort study of people living with HIV in Southern Africa

Author

Zaniewski, Elizabeth, Dao Ostinelli, Cam H, Chammartin, Frédérique, Maxwell, Nicola, Davies, Mary-Ann, Euvrard, Jonathan, Van Dijk, Janneke, Bosomprah, Samuel, Phiri, Sam, Tanser, Frank, Sipambo, Nosisa, Muhairwe, Josephine, Fatti, Geoffrey, Prozesky, Hans, Wood, Robin, Ford, Nathan, Fox, Matthew P, and Egger, Matthias

Subjects
610 Medicine & health, 360 Social problems & social services, 3. Good health
Abstract

INTRODUCTION The World Health Organization (WHO) recommends a CD4 cell count before starting antiretroviral therapy (ART) to detect advanced HIV disease, and routine viral load (VL) testing following ART initiation to detect treatment failure. Donor support for CD4 testing has declined to prioritize access to VL monitoring. We examined trends in CD4 and VL testing among adults (≥15 years of age) starting ART in Southern Africa. METHODS We analysed data from 14 HIV treatment programmes in Lesotho, Malawi, Mozambique, South Africa, Zambia and Zimbabwe in 2005 to 2018. We examined the frequency of CD4 and VL testing, the percentage of adults with CD4 or VL tests, and among those having a test, the percentage starting ART with advanced HIV disease (CD4 count 1000 HIV-RNA copies/mL) after ART initiation. We used mixed effect logistic regression to assess time trends adjusted for age and sex. RESULTS Among 502,456 adults, the percentage with CD4 testing at ART initiation decreased from a high of 78.1% in 2008 to a low of 38.0% in 2017; the probability declined by 14% each year (odds ratio (OR) 0.86; 95% CI 0.86 to 0.86). Frequency of CD4 testing also declined. The percentage starting ART with advanced HIV disease declined from 83.3% in 2005 to 23.5% in 2018; each year the probability declined by 20% (OR 0.80; 95% CI 0.80 to 0.81). VL testing after starting ART varied; 61.0% of adults in South Africa and 10.7% in Malawi were tested, but fewer than 2% were tested in the other four countries. The probability of VL testing after ART start increased only modestly each year (OR 1.06; 95% CI 1.05 to 1.06). The percentage with unsuppressed VL was 8.6%. There was no evidence of a decrease in unsuppressed VL over time (OR 1.00; 95% CI 0.99 to 1.01). CONCLUSIONS CD4 cell counting declined over time, including testing at the start of ART, despite the fact that many patients still initiated ART with advanced HIV disease. Without CD4 testing and expanded VL testing many patients with advanced HIV disease and treatment failure may go undetected, threatening the effectiveness of ART in sub-Saharan Africa.

11. Additional file 1: of The HOSENG trial â Effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage: protocol of a cluster-randomized clinical trial in rural Lesotho

Author

Amstutz, Alain, Thabo Lejone, Lefu Khesa, Muhairwe, Josephine, Bienvenu Nsakala, Katleho Tlali, Bresser, Moniek, Vanobberghen, Fiona, Mathebe Kopo, Mpho Kao, Klimkait, Thomas, Battegay, Manuel, Labhardt, Niklaus, and Glass, Tracy

Subjects
behavioral disciplines and activities, 3. Good health
Abstract

Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 Checklist: recommended items to address in a clinical trial protocol and related documents*. (PDF 82 kb)

12. SESOTHO trial ('Switch Either near Suppression Or THOusand') - switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, randomized clinical trial in Lesotho, Southern Africa

Author

Amstutz, Alain, Nsakala, Bienvenu Lengo, Vanobberghen, Fiona, Muhairwe, Josephine, Glass, Tracy Renée, Achieng, Beatrice, Sepeka, Mamorena, Tlali, Katleho, Sao, Lebohang, Thin, Kyaw, Klimkait, Thomas, Battegay, Manuel, and Labhardt, Niklaus Daniel

Subjects
3. Good health

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