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Start Over Author "Schlegel, Andrea" Topic 10217 clinic for visceral and transplantation surgery
14 results on '"Schlegel, Andrea"'

1. A Multicentre Outcome Analysis to Define Global Benchmarks for Donation after Circulatory Death Liver Transplantation

Author

Schlegel, Andrea, van Reeven, Marjolein, Croome, Kristopher, Parente, Alessandro, Dolcet, Annalisa, Widmer, Jeannette, Meurisse, Nicolas, De Carlis, Riccardo, Hessheimer, Amelia, Jochmans, Ina, Mueller, Matteo, van Leeuwen, Otto B, Nair, Amit, Tomiyama, Koji, Sherif, Ahmed, Elsharif, Mohamed, Kron, Philipp, van der Helm, Danny, Borja-Cacho, Daniel, Bohorquez, Humberto, Germanova, Desislava, Dondossola, Daniele, Olivieri, Tiziana, Camagni, Stefania, Gorgen, Andre, Patrono, Damiano, Cescon, Matteo, Croome, Sarah, Panconesi, Rebecca, Carvalho, Mauricio Flores, et al, and University of Zurich

Subjects
Hepatology, 610 Medicine & health, 2721 Hepatology, 10217 Clinic for Visceral and Transplantation Surgery
Published
2022

3. Response to the Comment on 'Injury or Function-What Is Best to Assess Organ Viability Before Liver Graft Implantation?'

Author

Muller Xavier, Philipp Dutkowski, Schlegel Andrea, Clavien Pierre-Alain, University of Zurich, and Dutkowski, Philipp

Subjects
Organ Viability, Tissue Survival, medicine.medical_specialty, business.industry, Urology, 610 Medicine & health, Organ Preservation, 2746 Surgery, Liver Transplantation, Liver graft, Liver, Medicine, Humans, Surgery, business, Function (biology), 10217 Clinic for Visceral and Transplantation Surgery
Published
2020

4. Hypothermic Oxygenated Liver Perfusion (HOPE) Prevents Tumor Recurrence in Liver Transplantation From Donation After Circulatory Death

Author

Mueller, Matteo, Kalisvaart, Marit, O'Rourke, Joanne, Shetty, Shishir, Parente, Alessandro, Muller, Xavier, Isaac, John, Muellhaupt, Beat, Muiesan, Paolo, Shah, Tahir, Clavien, Pierre-Alain, Schlegel, Andrea, Dutkowski, Philipp, and University of Zurich

Subjects
10219 Clinic for Gastroenterology and Hepatology, 610 Medicine & health, 10217 Clinic for Visceral and Transplantation Surgery, 2746 Surgery
Published
2020

6. Normothermic regional perfusion – What is the benefit?

Author

Schlegel, Andrea, Muiesan, Paolo, Dutkowski, Philipp, University of Zurich, and Dutkowski, Philipp

Subjects
610 Medicine & health, 2721 Hepatology, 10217 Clinic for Visceral and Transplantation Surgery
Published
2019

7. Performance validation of the ALPPS risk model

Author

Linecker, Michael, Kuemmerli, Christoph, Kambakamba, Patryk, Schlegel, Andrea, Muiesan, Paolo, Capobianco, Ivan, Nadalin, Silvio, Torres, Orlando J, Mehrabi, Arianeb, Stavrou, Gregor A, Oldhafer, Karl J, Lurje, Georg, Balci, Deniz, Lang, Hauke, Robles-Campos, Ricardo, Hernandez-Alejandro, Roberto, Malago, Massimo, De Santibanes, Eduardo, Clavien, Pierre-Alain, Petrowsky, Henrik, University of Zurich, and Petrowsky, Henrik

Subjects
610 Medicine & health, 2721 Hepatology, 2715 Gastroenterology, 10217 Clinic for Visceral and Transplantation Surgery
Published
2019

9. How much liver needs to be transected in ALPPS? A translational study investigating the concept of less invasiveness

Author

Linecker, Michael, Kambakamba, Patryk, Reiner, Cäcilia S, Linh Nguyen-Kim, Thi Dan, Stavrou, Gregor A, Jenner, Robert M, Oldhafer, Karl J, Björnsson, Bergthor, Schlegel, Andrea, Györi, Georg, Schneider, Marcel André, Lesurtel, Mickael, Clavien, Pierre-Alain, Petrowsky, Henrik, University of Zurich, and Petrowsky, Henrik

Subjects
10042 Clinic for Diagnostic and Interventional Radiology, 610 Medicine & health, Surgery, 10217 Clinic for Visceral and Transplantation Surgery, 2746 Surgery
Published
2017

11. In vivorisk evaluation of carbon-coated iron carbide nanoparticles based on short- and long-term exposure scenarios

Author

Herrmann, Inge K, Beck-Schimmer, Beatrice, Schumacher, Christoph M, Gschwind, Sabrina, Kaech, Andres, Ziegler, Urs, Clavien, Pierre-Alain, Günther, Detlef, Stark, Wendelin J, Graf, Rolf, Schlegel, Andrea A, University of Zurich, and Herrmann, Inge K

Subjects
1502 Bioengineering, 10216 Institute of Anesthesiology, 2204 Biomedical Engineering, 610 Medicine & health, 2701 Medicine (miscellaneous), 10024 Center for Microscopy and Image Analysis, 2500 General Materials Science, 10217 Clinic for Visceral and Transplantation Surgery
Published
2016

13. Low Platelet Counts after Liver Transplantation Predict Early Post-Transplant Survival: The '60-5 Criterion'

Author

Lesurtel, Mickaël, Raptis, Dimitri A, Melloul, Emmanuel, Schlegel, Andrea, Oberkofler, Christian, El-Badry, Ashraf Mohammad, Weber, Annina, Mueller, Nicolas, Dutkowski, Philipp, Clavien, Pierre-Alain, and University of Zurich

Subjects
10234 Clinic for Infectious Diseases, 2747 Transplantation, 610 Medicine & health, 2721 Hepatology, 10217 Clinic for Visceral and Transplantation Surgery, 2746 Surgery
Published
2014

14. Viability Assessment in Liver Transplantation—What Is the Impact of Dynamic Organ Preservation?

Author

Mauricio Flores Carvalho, Andrea Schlegel, Paolo Muiesan, Philipp Dutkowski, Matteo Mueller, David Meierhofer, Rebecca Panconesi, University of Zurich, and Schlegel, Andrea

Subjects
medicine.medical_specialty, medicine.medical_treatment, Cold storage, Medicine (miscellaneous), 610 Medicine & health, Genetics and Molecular Biology, Review, 030230 surgery, Liver transplantation, Bioinformatics, viability testing, General Biochemistry, Genetics and Molecular Biology, Cholangiocyte, Organ transplantation, 03 medical and health sciences, 0302 clinical medicine, 1300 General Biochemistry, Genetics and Molecular Biology, Medicine, Clinical significance, lcsh:QH301-705.5, 10217 Clinic for Visceral and Transplantation Surgery, Machine perfusion, liver transplantation, business.industry, machine perfusion, 2701 Medicine (miscellaneous), Transplantation, mitochondria, lcsh:Biology (General), General Biochemistry, 030211 gastroenterology & hepatology, Liver function, business
Abstract

Based on the continuous increase of donor risk, with a majority of organs classified as marginal, quality assessment and prediction of liver function is of utmost importance. This is also caused by the notoriously lack of effective replacement of a failing liver by a device or intensive care treatment. While various parameters of liver function and injury are well-known from clinical practice, the majority of specific tests require prolonged diagnostic time and are more difficult to assess ex situ. In addition, viability assessment of procured organs needs time, because the development of the full picture of cellular injury and the initiation of repair processes depends on metabolic active tissue and reoxygenation with full blood over several hours or days. Measuring injury during cold storage preservation is therefore unlikely to predict the viability after transplantation. In contrast, dynamic organ preservation strategies offer a great opportunity to assess organs before implantation through analysis of recirculating perfusates, bile and perfused liver tissue. Accordingly, several parameters targeting hepatocyte or cholangiocyte function or metabolism have been recently suggested as potential viability tests before organ transplantation. We summarize here a current status of respective machine perfusion tests, and report their clinical relevance.

Published
2021

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