1. Use of clobetasol in lacquer for plaque psoriasis treatment
- Author
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Paulo Eduardo Neves Ferreira Velho, Renata Ferreira Magalhães, Suze Aparecida da Silva, Rafael Augusto Tamasauskas Torres, and Raquel Diana de Oliveira
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Administration, Topical ,Statistical difference ,Therapeutics ,Dermatology ,Severity of Illness Index ,Lacquer ,030207 dermatology & venereal diseases ,03 medical and health sciences ,FAVORABLE RESPONSE ,Young Adult ,0302 clinical medicine ,Quality of life ,Double-Blind Method ,Psoriasis ,Surveys and Questionnaires ,medicine ,Humans ,Prospective Studies ,Glucocorticoids ,Aged ,Plaque psoriasis ,Aged, 80 and over ,Clobetasol ,business.industry ,Communication ,Middle Aged ,medicine.disease ,Treatment Outcome ,030220 oncology & carcinogenesis ,visual_art ,RL1-803 ,visual_art.visual_art_medium ,Quality of Life ,Female ,Pharmaceutical Vehicles ,Skin lesion ,business - Abstract
Clobetasol benefits to control psoriasis lesions are well defined, but there were not studies about its action when used in lacquer vehicle to control skin lesions. A double-blind study was conducted with 40 patients that utilized clobetasol 0.05% in one hemibody and just the vehicle in the other hemibody. Twenty of them used petrolatum as vehicle and the others used lacquer. An assessment was conducted using the clinical index PASI and a quality of life questionnaire (Dermatological Life Quality Index). There was no statistical difference between groups. There was a trend of favorable response particularly in the hemibody treated with clobetasol.
- Published
- 2016