1. Physical activity is associated with improved bone health in children with inflammatory bowel disease
- Author
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Elodie Drumez, Claire Spyckerelle, Florian Vidal, Djamal Djeddi, Céline Legrand, Eve Devouge, Dominique Turck, Serge Ganga Zandzou, Frédéric Gottrand, Stéphanie Coopman, Delphine Ley, Laurent Béghin, Laurent Michaud, Jérémy Vanhelst, Université de Lille, Inserm, CHU Lille, Lille Inflammation Research International Center - U 995 [LIRIC], Evaluation des technologies de santé et des pratiques médicales - ULR 2694 [METRICS], CHU Amiens-Picardie, Groupe Hospitalier Artois-Ternois Centre Hospitalier d’Arras, Hôpital Saint Vincent de Paul de Lille, Lille Inflammation Research International Center - U 995 (LIRIC), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Evaluation des technologies de santé et des pratiques médicales - ULR 2694 (METRICS), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Groupe Hospitalier de l'Institut Catholique de Lille (GHICL), Centre Hospitalier de Roubaix, Centre hospitalier de Béthune, Groupement des Hôpitaux de l'Institut Catholique de Lille (GHICL), Université catholique de Lille (UCL)-Université catholique de Lille (UCL), and Université de Lille, LillOA
- Subjects
Male ,0301 basic medicine ,medicine.medical_specialty ,Time Factors ,Adolescent ,[SDV]Life Sciences [q-bio] ,Osteoporosis ,030209 endocrinology & metabolism ,Fitness Trackers ,Critical Care and Intensive Care Medicine ,Bone health ,Inflammatory bowel disease ,Pediatrics ,03 medical and health sciences ,Absorptiometry, Photon ,0302 clinical medicine ,Quality of life ,Bone Density ,Internal medicine ,medicine ,Bone mineral density ,Humans ,Healthy Lifestyle ,Child ,Exercise ,2. Zero hunger ,Bone mineral ,Inflammation ,030109 nutrition & dietetics ,Nutrition and Dietetics ,Lifestyle habits ,business.industry ,Confounding ,Inflammatory Bowel Diseases ,medicine.disease ,Actigraphy ,3. Good health ,[SDV] Life Sciences [q-bio] ,Osteopenia ,Bone Diseases, Metabolic ,Quality of Life ,Female ,business ,Body mass index - Abstract
Bone health is an important concern in patients with inflammatory bowel disease (IBD). Low bone mineral density (BMD) is a powerful predictor of fracture risk in IBD patients. Physical activity (PA) plays an important role in bone health. However, PA data for children and adolescents with IBD are scarce. The primary aim is to evaluate the relationship between PA and BMD in children with IBD. The secondary aim was to assess the relationship between PA and quality of life. Eighty-four IBD paediatric patients (45 boys) aged 14.3 ± 2.7 years were included (disease activity: (i) remission, n = 62; (ii) mild, n = 18; (iii) severe disease, n = 1). BMD was measured using dual-energy X-ray absorptiometry and expressed as age- and sex-based Z-scores. Each patient wore a triaxial accelerometer for seven consecutive days for objective PA quantification. Quality of life was assessed using the PedsQL™ and energy intake was assessed prospectively for three days using a dietary diary. BMD Z-score was -0.96 ± 1.11. Only five patients (6%) fulfilled the recommendation of 60 min of daily moderate-to-vigorous PA (MVPA). The proportion of children with osteopenia and osteoporosis was 51% and 4%, respectively. After adjustment for confounders (pubertal status and body mass index), total PA and time in MVPA were positively associated with BMD (regression coefficient per one standard deviation increase in PA parameters = 0.26; P
- Published
- 2020