8 results on '"Dong Min Jang"'
Search Results
2. Anaphylactic Shock After Indocyanine Green Video Angiography During Cerebrovascular Surgery
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Jae Sung Ahn, Joung-Uk Kim, Seung Il Ha, M. H. Kim, Seungjoo Lee, Jung Cheol Park, Wonhyoung Park, and Dong-Min Jang
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Indocyanine Green ,genetic structures ,Provocation test ,Neurosurgical Procedures ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Aneurysm ,Medicine ,Humans ,Anaphylaxis ,Dexamethasone ,Aged ,medicine.diagnostic_test ,business.industry ,Angiography, Digital Subtraction ,Intracranial Aneurysm ,Middle Aged ,medicine.disease ,eye diseases ,Cerebral Angiography ,body regions ,Blood pressure ,chemistry ,030220 oncology & carcinogenesis ,Anesthesia ,Angiography ,Surgery ,Female ,Neurology (clinical) ,business ,Cerebrovascular surgery ,Indocyanine green ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Background Indocyanine green (ICG) video angiography has been widely used in cerebrovascular surgery. ICG injection is generally safe, with a low incidence of complications. ICG-related anaphylactic reactions during neurosurgery have been rarely reported. We report the cases of 2 patients who had experienced anaphylactic shock in response to intravenous ICG injection (DID Indocyanine Green [Dongindang, Inc., Gyeonggi-do, Republic of Korea]) during intracranial aneurysm (IA) surgery. Case Description The first patient, a 69-year-old woman with an unruptured IA, had been undergoing clipping surgery under general anesthesia. Immediately after ICG injection, her blood pressure suddenly decreased from 140/80 mm Hg to 50/30 mm Hg and she developed a skin rash on her abdomen and all extremities. Chest compression was initiated, and her vital signs gradually recovered to their pre-ICG levels within 10 minutes. The second patient was a 58-year-old woman with an unruptured IA who had been undergoing clipping surgery. After ICG injection, her blood pressure had decreased from 130/80 mm Hg to 60/40 mm Hg, and a rash-like skin lesion was observed on her abdomen. After intravenous injection of norepinephrine and dexamethasone, her blood pressure recovered to its pre-ICG level within 30 minutes and remained stable thereafter. The postoperative ICG skin provocation test findings were positive for both patients; however, only 1 patient showed markedly increased serum tryptase levels. Conclusion Despite the rarity of ICG-related anaphylaxis, clinicians should be aware of this unexpected, but potentially life-threatening, drug reaction in patients undergoing cerebrovascular surgery.
- Published
- 2019
3. Effect of Prone Positional Apparatus on the Occurrence of Acute Kidney Injury After Spine Surgery
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Sung-Hoon Kim, Christopher I. Shaffrey, Dongseop Kim, Woo-Hyun Shim, Yong-Seok Park, Bhiken I. Naik, Seok-Joon Jin, and Dong-Min Jang
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Adult ,Male ,medicine.medical_specialty ,Operative Time ,Blood Loss, Surgical ,Hemodynamics ,Operating Tables ,Patient Positioning ,03 medical and health sciences ,0302 clinical medicine ,Spine surgery ,Postoperative Complications ,Blood loss ,medicine ,Clinical endpoint ,Pressure ,Prone Position ,Humans ,Propensity Score ,Aged ,business.industry ,Incidence (epidemiology) ,Acute kidney injury ,Abdominal Cavity ,Acute Kidney Injury ,Middle Aged ,medicine.disease ,Spine ,Surgery ,Prone position ,030220 oncology & carcinogenesis ,Propensity score matching ,Female ,Neurology (clinical) ,business ,Erythrocyte Transfusion ,030217 neurology & neurosurgery - Abstract
Increased intra-abdominal pressure with prone positioning for spinal surgery is associated with intraoperative hemodynamic alterations and the potential for postoperative complications. This study investigated the incidence of postoperative acute kidney injury (AKI) in patients undergoing spine surgery on a Jackson spinal table or a Wilson frame.A total of 1374 patients who underwent spine surgery were divided into 2 groups: Jackson spinal table (n = 598) and Wilson frame group (n = 776). After 1:1 propensity score matching, a final analysis was performed on 970 patients. The primary endpoint was a comparison of the incidence of AKI in the 2 groups.After propensity score matching analysis, the mean ± standard deviations of spine surgery invasiveness index were 4.7 ± 3.5 and 2.1 ± 1.4 in patients with the Jackson spinal table and the Wilson frame, respectively (P 0.001). Considering the differences in surgical invasiveness, operative time, estimated blood loss, and administration of packed red blood cells were higher in the Jackson spinal table group than in the Wilson frame group (P0.001). However, the incidence of AKI was less with the Jackson spinal table than with the Wilson frame (1.7% vs. 3.7%, 2.25 [0.978-5.175], P = 0.056), not reaching statistical significance.This analysis showed that postoperative AKI in patients undergoing spine surgery in the prone position was not different with the Wilson frame than in the Jackson spinal table despite higher surgical severity, longer operative times, and more blood loss in the latter group. In spine surgery, the appropriate selection of prone positioning apparatus can potentially be an important consideration in reducing the risk of AKI.
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- 2018
4. Changes of diaphragmatic excursion and lung compliance during major laparoscopic pelvic surgery: A prospective observational study
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Hwanhee Yoo, Hong Soon Kim, Kyungmi Kim, Woo-Jong Choi, Jong Yeon Park, and Dong-Min Jang
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Male ,medicine.medical_treatment ,Trendelenburg position ,General Anesthesia ,Respiratory System ,Social Sciences ,Pulmonary compliance ,Diagnostic Radiology ,Head-Down Tilt ,0302 clinical medicine ,Pneumoperitoneum ,030202 anesthesiology ,Anesthesiology ,Ultrasound Imaging ,Thoracic Diaphragm ,Medicine and Health Sciences ,Medicine ,Intubation ,Psychology ,Anesthesia ,Prospective Studies ,Lung Compliance ,Multidisciplinary ,Pharmaceutics ,Radiology and Imaging ,Middle Aged ,Muscle relaxation ,Sedation ,Female ,medicine.symptom ,Anatomy ,Research Article ,Imaging Techniques ,Science ,Movement ,Diaphragm ,Surgical and Invasive Medical Procedures ,Research and Analysis Methods ,Pelvis ,03 medical and health sciences ,Drug Therapy ,Diagnostic Medicine ,Humans ,Radical Hysterectomy ,Pharmacology ,business.industry ,Biology and Life Sciences ,Relaxation (Psychology) ,030208 emergency & critical care medicine ,medicine.disease ,body regions ,Laparoscopy ,Diaphragmatic excursion ,business ,Pneumoperitoneum, Artificial - Abstract
Major laparoscopic pelvic surgery requires steep Trendelenburg position with pneumoperitoneum for a long time. We investigated the effect of Trendelenburg position with pneumoperitoneum on diaphragmatic excursion and lung compliance during major laparoscopic pelvic surgery using M-mode sonography. Twenty patients undergoing elective pelviscopic radical hysterectomy were included in this study. Diaphragmatic excursion was measured at the following time points; after sedation, after intubation, 90 minutes after Trendelenburg position with pneumoperitoneum, and after operation with recovery of muscle relaxation. And lung compliance was measured using anesthetic machine under general anesthesia; after the intubation, 90 minutes after Trendelenburg position with pneumoperitoneum and after operation with recovery of muscle relaxation. In order to detect postoperative pulmonary complication, postoperative chest radiography was checked. Static lung compliance, dynamic lung compliance and diaphragmatic excursion were decreased during operation (P < 0.001, respectively). At the end of the operation with recovery of muscle relaxation, reduced diaphragmatic movement was not recovered as its excursion after sedation (P < 0.001). In conclusion, lung compliance was decreased following transiently decreased diaphragmatic excursion during major laparoscopic pelvic surgery.
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- 2018
5. Cerebral air embolism and subsequent transient neurologic abnormalities in a liver transplant recipient following the removal of the pulmonary artery catheter from the central venous access device: a case report
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In-Gu Jun, Dong Min Jang, Jinwook Lim, Young-Kug Kim, Gyu-Sam Hwang, and Sun Key Kim
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medicine.medical_specialty ,medicine.medical_treatment ,Case Report ,Liver transplantation ,Air embolism ,lcsh:RD78.3-87.3 ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,030216 legal & forensic medicine ,liver transplantation ,business.industry ,Neurological status ,Pulmonary artery catheter ,medicine.disease ,Venous access ,Surgery ,Liver transplant recipient ,Anesthesiology and Pain Medicine ,air embolism ,lcsh:Anesthesiology ,Neurologic abnormalities ,Cardiology ,Complication ,business ,central venous catheters ,030217 neurology & neurosurgery - Abstract
Cerebral air embolism is a rare but potentially life-threatening complication. We experienced a living-donor liver transplant recipient who presented with unexpected cerebral air embolism and transient neurologic abnormalities that subsequently developed just after the removal of the pulmonary artery catheter from the central venous access device. One day after the initial event, the patient's neurologic status gradually improved. The patient was discharged 30 days after liver transplantation without neurologic sequelae.
- Published
- 2016
6. Efficiency of a New Mesh-Type Nebulizer (NE-SM1 NEPLUS) for Intrapulmonary Delivery of Ipratropium Bromide in Surgical Patients
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Soo Han Lee, Eun Kyung Lee, Dong Min Jang, Yong Hun Lee, Byung Moon Choi, Gu Youn Kwon, Ji-Yeon Bang, Gyu-Jeong Noh, and Do Yang Park
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,Population ,Pilot Projects ,Anesthesia, General ,Ipratropium bromide ,Toxicology ,03 medical and health sciences ,Drug Delivery Systems ,0302 clinical medicine ,Pharmacokinetics ,Administration, Inhalation ,Humans ,Medicine ,Particle Size ,education ,Lung ,Aerosols ,Pharmacology ,Volume of distribution ,Mechanical ventilation ,education.field_of_study ,Inhalation ,business.industry ,Ipratropium ,Nebulizers and Vaporizers ,030208 emergency & critical care medicine ,General Medicine ,Middle Aged ,Models, Theoretical ,respiratory system ,Respiration, Artificial ,Bronchodilator Agents ,Surgery ,Nebulizer ,Respiratory Tract Absorption ,030228 respiratory system ,Elective Surgical Procedures ,Anesthesia ,business ,medicine.drug ,Surgical patients - Abstract
This study was aimed to evaluate the efficiency of a new mesh-type nebulizer for the intrapulmonary delivery of ipratropium bromide in surgical patients under mechanical ventilation. A total of 20 patients were randomly allocated to receive 0.5 mg ipratropium bromide using either a control (Pariboy SX, Pari, Co., Starnberg, Germany, n = 10) or test (NE-SM1 NEPLUS, KTMED INC., Seoul, Korea, n = 10) nebulizer during general anaesthesia. Ipratropium bromide was nebulized continuously for 20 min. in each group. Plasma concentrations of ipratropium bromide were obtained from blood samples at preset intervals. Non-compartmental analysis of ipratropium bromide was performed to compare the efficiency of pulmonary drug delivery in both nebulizers. Population pharmacokinetic analysis of ipratropium bromide was performed. Additionally, the noise level during the nebulizer operation and the aerosol particle size for each device were measured. The dose-normalized AUC(last) was 0.10 min/L for both nebulizers. The pharmacokinetics of nebulized ipratropium bromide can be described best by a one-compartment model with first-order absorption. The apparent volume of distribution and metabolic clearance were 1340 L and 6.78 L/min, respectively. Type of nebulizer was a significant covariate for absorption rate constant. The equivalent sound level and median aerosol particle diameter were 35.0 dB and 4.52 μm for the test nebulizer, and 60.2 dB and 3.85 μm for the control nebulizer, respectively. From the standpoint of the dose-normalized AUC(last) , a new vibrating mesh-type nebulizer shows similar performance in the intrapulmonary delivery of ipratropium bromide to that of a jet-type nebulizer in surgical patients.
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- 2015
7. Detecting Mind-Wandering from Eye Movement and Oculomotor Data during Learning Video Lecture
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Il Ho Yang, Seong Un Kim, and Dong-Min Jang
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medicine.medical_specialty ,Public Administration ,Physical Therapy, Sports Therapy and Rehabilitation ,Audiology ,050105 experimental psychology ,eye- movements ,Education ,03 medical and health sciences ,0302 clinical medicine ,Mind-wandering ,Developmental and Educational Psychology ,Computer Science (miscellaneous) ,medicine ,Video lecture ,0501 psychology and cognitive sciences ,05 social sciences ,self-caught method ,Attentional control ,Eye movement ,mind-wandering ,cognitive_experimental_psychology ,oculomotor data ,Computer Science Applications ,Peak velocity ,Duration (music) ,video lecture ,Saccade ,Fixation (visual) ,lcsh:L ,Maximum amplitude ,030217 neurology & neurosurgery ,lcsh:Education - Abstract
The purpose of this study was to detect mind-wandering experienced by pre-service teachers during a video learning lecture on physics. The lecture was videotaped and consisted of a live lecture in a classroom. The lecture was about Gauss's law on physics. We investigated whether oculomotor data and eye movements could be used as a marker to indicate the learner&rsquo, s mind-wandering. Each data was collected in a study in which 24 pre-service teachers (16 females and 8 males) reported mind-wandering experience through self-caught method while learning physics video lecture during 30 minutes. A Tobii Pro Spectrum (sampling rate: 300 Hz) was used to capture their eye-gaze during learning Gauss's law through a course video. After watching the video lecture, we interviewed pre-service teachers about their mind-wandering experience. We first used the self-caught method to capture the mind-wandering timing of pre-service teachers while learning from video lectures. We detected more accurate mind-wandering segments by comparing fixation duration and saccade count. We investigated two types of oculomotor data (blink count, pupil size) and nine eye movements (average peak velocity of saccades, maximum peak velocity of saccades, standard deviation of peak velocity of saccades, average amplitude of saccades, maximum amplitude of saccades, total amplitude of saccades, saccade count/s, fixation duration, fixation dispersion). The result was that the blink count could not be used as a marker for mind-wandering during learning video lectures among them (oculomotor data and eye movements), unlike previous literatures. Based on the results of this study, we identified elements that can be used as mind-wandering markers while learning from video lectures that are similar to real classes, among the oculomotor data and eye movement mentioned in previous literatures. Additionally, we found that most participants focused on past thoughts and felt unpleasant after experiencing mind-wandering through interview analysis.
- Published
- 2020
8. Centipedegrass extracts regulate LPS-mediated aberrant immune responses by inhibiting Janus kinase
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Remigius Ambrose Kawala, Dong-Min Jang, Hyoung-Woo Bai, Seung Sik Lee, Byung Yeoup Chung, and Chul‑Hong Park
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Lipopolysaccharides ,Male ,Lipopolysaccharide ,Pharmaceutical Science ,Administration, Oral ,Nitric Oxide Synthase Type II ,Nitric Oxide ,Poaceae ,Nitric oxide ,03 medical and health sciences ,chemistry.chemical_compound ,Mice ,0302 clinical medicine ,Immune system ,Drug Discovery ,Animals ,Janus Kinase Inhibitors ,Kinase activity ,Phosphorylation ,030304 developmental biology ,Pharmacology ,0303 health sciences ,biology ,Dose-Response Relationship, Drug ,Kinase ,Plant Extracts ,JAK-STAT signaling pathway ,Janus Kinase 2 ,Cell biology ,Nitric oxide synthase ,Mice, Inbred C57BL ,RAW 264.7 Cells ,Complementary and alternative medicine ,chemistry ,030220 oncology & carcinogenesis ,biology.protein ,Molecular Medicine ,Mitogen-Activated Protein Kinases ,Janus kinase - Abstract
Background Centipedegrass extract (CGE) is rich in several polyphenolic compounds including C-glycosylflavonoids, such as maysin and its derivatives, and exerts antioxidant, anti-adipogenic and anticancer effects. However, the effect of CGE on the immune system is unclear. Purpose CGE might inhibit NO production induced by lipopolysaccharide (LPS). In this study, we propose a molecular mechanism for regulation of aberrant immune responses by CGE in LPS-stimulated RAW264.7 cells. Study Design We will preparation of Centipedegrass extract and purify partially in rich of maysin and its derivatives. And examine the effect of the CGE on immune system using LPS-induced RAW cells and animals. Methods LPS-induced nitric oxide (NO) and interleukin-6 levels were measured by enzyme-linked immunosorbent assay. The mRNA and protein levels of immune mediators were analyzed by reverse-transcription polymerase chain reaction and immunoblotting, respectively. Results CGE inhibited LPS-induced NO production in a concentration-dependent manner by suppressing inducible nitric oxide synthase (iNOS) expression in LPS-stimulated cells; this effect was mediated by inhibition of the JAK/STAT pathway. However, CGE did not regulate the expression of other factors, including phosphorylated p38, c-jun N-terminal kinase, or extracellular signal-regulated kinase 1/2. In addition, CGE increased T cells percentage in peripheral blood after oral administration. Conclusion These results indicate that CGE suppresses LPS-induced production of NO and expression of iNOS by directly inhibiting JAK2 kinase activity and enhancing effects on the immune system in mice.
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- 2017
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