1. Acute benign vertebral compression fractures: 'see-through sign' on contrast-enhanced MR images
- Author
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Joong Mo Ahn, Joon Woo Lee, Bo Reum Yoo, Guen Young Lee, Heung Sik Kang, Yoon Joo Shin, Woo Young Kang, Eugene Lee, and Jinyoung Lee
- Subjects
Adult ,Male ,medicine.medical_specialty ,Intraclass correlation ,Contrast Media ,Sensitivity and Specificity ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Cohen's kappa ,Predictive Value of Tests ,Fractures, Compression ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Aged ,Retrospective Studies ,Aged, 80 and over ,Spinal Neoplasms ,business.industry ,Vertebral compression fracture ,Middle Aged ,Institutional review board ,medicine.disease ,Magnetic Resonance Imaging ,Surgery ,Trabecular bone ,Fractures, Spontaneous ,030220 oncology & carcinogenesis ,Spinal Fractures ,Female ,Neurosurgery ,Radiology ,Mr images ,business ,Sign (mathematics) - Abstract
To retrospectively evaluate the diagnostic role of the contrast-enhanced MRI (CE-MRI) for differentiation between benign VCFs and malignant VCFs focusing on the internal transparent trabecular bone on CE-MRI (the “see-through sign”). The institutional review board approved this study and informed consent was waived due to the retrospective nature of the study. From January 2012 to December 2013, all 149 consecutive benign or malignant VCF patients were enrolled for consideration in this study from a CE-MRI database. In the first analysis, four radiologists independently evaluated the presence or absence of the see-through sign. The see-through sign was defined as internal transparent trabecular bone morphology on CE-MRI. The intraclass correlation coefficient (ICC), percentage agreement, and Fleiss’s kappa statistics were obtained. Fifty-seven patients (M:F = 27:30; mean age, 63 years; age range, 20–88 years) who diagnosed as acute benign (n = 24) and malignant (n = 33) VCFs were finally included for the analysis. The results of all readers showed that the see-through sign was associated with acute benign VCFs (p
- Published
- 2015