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Start Over Author "Annalisa Bastelli" Topic 0302 clinical medicine
2 results on '"Annalisa Bastelli"'

1. An area-based study on intrapartum antibiotic prophylaxis for preventing group B streptococcus early-onset disease: advances and limitations

Author

Luana Pini, Lucia Gambini, Alberto Berardi, Fabio Facchinetti, Irene Papa, Claudio Chiossi, Maria Grazia Capretti, Valentina Fiorini, Luigi Memo, Fabrizio Ferrari, Maria Letizia Bacchi Reggiani, Maria Vittoria Rizzo, Andrea Zucchini, Marcello Lanari, Cecilia Rossi, Annalisa Bastelli, Sara Gavioli, Berardi, Alberto, Rossi, Cecilia, Bacchi Reggiani, Maria Letizia, Bastelli, Annalisa, Capretti, Maria Grazia, Chiossi, Claudio, Fiorini, Valentina, Gambini, Lucia, Gavioli, Sara, Lanari, Marcello, Memo, Luigi, Papa, Irene, Pini, Luana, Rizzo, Maria Vittoria, Zucchini, Andrea, Facchinetti, Fabio, and Ferrari, Fabrizio

Subjects
medicine.medical_specialty, Group B streptococcus, Prom, Group B, sepsis, 03 medical and health sciences, 0302 clinical medicine, prevention, newborn, Pregnancy, Risk Factors, intrapartum antibiotic prophylaxis, risk factors, 030225 pediatrics, Positive predicative value, Streptococcal Infections, Medicine, Humans, 030212 general & internal medicine, Antibiotic prophylaxis, Full Term, Retrospective Studies, Group B streptococcu, Receiver operating characteristic, business.industry, Obstetrics, Rectum, Obstetrics and Gynecology, Odds ratio, Antibiotic Prophylaxis, Infectious Disease Transmission, Vertical, Anti-Bacterial Agents, Perinatal Care, intrapartum antibiotic prophylaxi, risk factor, Pediatrics, Perinatology and Child Health, Vagina, Gestation, Premature Birth, Ampicillin, Female, Guideline Adherence, business
Abstract

INTRODUCTION: The prevalence of maternal group-B-streptococcus (GBS) colonization and risk factors (RFs) for neonatal early-onset disease (EOD) in Europe are poorly defined. Large-scale information concerning adherence to recommendations for preventing GBS-EOD are lacking. MATERIALS AND METHODS: This was a 3-month retrospective area-based study including all regional deliveries ≥35 weeks' gestation (in 2012). The sensitivity, specificity, positive and negative predictive values, odds ratio and receiver operating characteristic (ROC) curve for intrapartum antibiotic prophylaxis (IAP) among full-term and preterm deliveries and prolonged membrane rupture (PROM) were calculated. RESULTS: Among 7133 women, 259 (3.6%) were preterm (35-36 weeks' gestation). Full-term women were 6874, and 876 (12.7%) had at least 1 RF. Most women (6495) had prenatal screening and 21.4% (1390) were GBS positive. IAP was given to 2369 (33.2%) women (preterm, n = 166; full term, n = 2203). Compared to full-term, preterm women were less likely to receive IAP when indicated (73.2% versus 90.3%, p

Published
2016

2. Clinical Data of Neonatal Systemic Thrombosis

Author

Paola Saracco, Rossana Bagna, Chiara Gentilomo, Mariella Magarotto, Alice Viano, Federica Magnetti, Paola Giordano, Matteo Luciani, Angelo Claudio Molinari, Agnese Suppiej, Luca Antonio Ramenghi, Paolo Simioni, Manuela Agostini, Annalisa Bastelli, Petrina Bastrenta, Antonio Belcastro, Anna Casani, Nadia Castellino, Daniela Farinasso, Marcella Gaffuri, Maria Rita Gallina, Elena Gallo, Lorenzo Giacchetti, Laura Ilardi, Nicola Laforgia, Donatella Lasagni, Ignazio Lofù, Fabio Lunetta, Francesco Messina, Barbara Perrone, Altea Petrucci, Andrea Pettenazzo, Fiammetta Piersigilli, Maurizio Radicioni, Antonella Tufano, and Luca Vecchiato

Subjects
Male, Pediatrics, Neonatal intensive care unit, population, 030204 cardiovascular system & hematology, 0302 clinical medicine, Models, Risk Factors, Thrombophilia, Registries, risk-factors, Anticoagulants, Arteries, Coronary Circulation, Data Collection, Female, Gestational Age, Humans, Infant, Newborn, Italy, Models, Statistical, Neonatology, Patient Discharge, Sepsis, Venous Thromboembolism, Human coagulation system, education.field_of_study, renal venous thrombosis, pediatric-patients, united-states, thromboembolism, thrombophilia, vasculopathy, management, Gestational age, Perinatology and Child Health, Statistical, Thrombosis, medicine.medical_specialty, Population, NO, 03 medical and health sciences, 030225 pediatrics, medicine, education, business.industry, Infant, Newborn, Placental disease, medicine.disease, Clinical trial, Pediatrics, Perinatology and Child Health, business
Abstract

Objective To evaluate clinical data and associated risk conditions of noncerebral systemic venous thromboembolism (VT), arterial thromboembolism (AT), and intracardiac thromboembolism (ICT) in neonates. Study design Data analysis of first systemic thromboembolism occurring in 75 live neonates (0-28 days), enrolled in the Italian Registry of Pediatric Thrombosis from neonatology centers between January 2007 and July 2013. Results Among 75 events, 41 (55%) were VT, 22 (29%) AT, and 12 (16%) ICT; males represented 65%, and 71% were preterm. In 19 (25%), thromboembolism was diagnosed on the first day of life. In this "early onset" group, prenatal-associated risk conditions (maternal/placental disease) were reported in 70% and inherited thrombophilia in 33%. Postnatal risk factors were present in 73%; infections and central vascular catheters in 56% and 54% VT, respectively, and in 67% ICT vs 27% AT ( Conclusions This report from the Registro Italiano Trombosi Infantili, although limited by representing an uncontrolled case series, can be used to develop future clinical trials on appropriate management and prevention of neonatal thrombosis, focusing on obstetrical surveillance and monitoring of critically ill neonates with vascular access. A thrombosis risk prediction rule specific for the neonatal population should be developed through prospective controlled studies.

Published
2016
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