1. Fatal Aspergillosis of the Renal Vasculature in a Combined Liver-Kidney Transplant Recipient
- Author
-
M A Thirunarayan, Chandrasekar H Pranatharthi, Anil Tarigopula, Ram Gopalakrishnan, Ramamurthy Anand, Vasant Nagvekar, and Vidya Devarajan
- Subjects
0301 basic medicine ,Microbiology (medical) ,Pathology ,medicine.medical_specialty ,030106 microbiology ,Immunology ,lcsh:QR1-502 ,kidney transplantation ,030230 surgery ,Aspergillosis ,Microbiology ,lcsh:Microbiology ,Primary hyperoxaluria ,03 medical and health sciences ,0302 clinical medicine ,Immunology and Microbiology (miscellaneous) ,medicine ,Immunology and Allergy ,Kidney transplantation ,Aspergillus ,General Immunology and Microbiology ,biology ,business.industry ,medicine.disease ,biology.organism_classification ,Transplantation ,Kidney transplant recipient ,Haematopoiesis ,Infectious Diseases ,perfusate ,Stem cell ,business - Abstract
Invasive aspergillosis remains a problem in solid organs and haematopoietic stem cell transplants. We report a case of 12-year-old female with primary hyperoxaluria with regular haemodialysis for the end-stage renal disease. She underwent a combined liver and renal transplantation which got infected by aspergillosis. In this case study, it is speculated that the most likely source of Aspergillus was contaminated preservative solution (perfusate), resulting in infection within the donor kidney and subsequent systemic infection in the recipient. This case study calls for critical analysis and needs for the routine culture of the preservative solution before transplantation, to detect any fungal contamination and manage it prophylactically.
- Published
- 2018
- Full Text
- View/download PDF