1. Chloroquine Cardiotoxicity Leading to Cardiogenic Shock
- Author
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Meghan E. Kapp, Madeleine Alder, JoAnn Lindenfeld, Giovanni Davogustto, and Richa Gupta
- Subjects
0301 basic medicine ,medicine.medical_specialty ,antimalarial toxicity ,Heart block ,acute heart failure ,Cardiomyopathy ,Autopsy ,030105 genetics & heredity ,03 medical and health sciences ,0302 clinical medicine ,Refractory ,Chloroquine ,CMR, cardiac magnetic resonance ,Internal medicine ,LVEF, left ventricular ejection fraction ,medicine ,Diseases of the circulatory (Cardiovascular) system ,LV, left ventricular ,Cardiotoxicity ,BNP, brain natriuretic peptide ,business.industry ,Cardiogenic shock ,AV, atrioventricular ,systolic heart failure ,Mini-Focus Issue: Heart Failure ,Case Report: Heart Care Team/Multidisciplinary Team Live ,medicine.disease ,chronic heart failure ,RC666-701 ,Circulatory system ,endomyocardial biopsy ,Cardiology ,EMB, endomyocardial biopsy ,AMIC, antimalaria-induced cardiomyopathy ,Cardiology and Cardiovascular Medicine ,business ,AM, antimalarial medication ,cardiomyopathy ,030217 neurology & neurosurgery ,medicine.drug - Abstract
A patient with a history of heart block and longstanding chloroquine use presented in cardiogenic shock refractory to medical therapy and mechanical circulatory support. Autopsy supported antimalarial-induced cardiomyopathy (AMIC). Progression of AMIC may be halted with early recognition and cessation of antimalarial therapy, highlighting importance of screening and timely diagnosis. (Level of Difficulty: Beginner.), Graphical abstract
- Published
- 2020