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18 results on '"Joshua N. Leonard"'

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1. The COMET toolkit for composing customizable genetic programs in mammalian cells

2. Development of novel metabolite-responsive transcription factors via transposon-mediated protein fusion

3. Building with intent: Technologies and principles for engineering mammalian cell-based therapies to sense and respond

4. A Systematic Evaluation of Factors Affecting Extracellular Vesicle Uptake by Breast Cancer Cells

5. Multiplexing Engineered Receptors for Multiparametric Evaluation of Environmental Ligands

6. Engineering Modular Biosensors to Confer Metabolite-Responsive Regulation of Transcription

7. Regulation of the IL-10-driven macrophage phenotype under incoherent stimuli

8. Adding energy minimization strategy to peptide-design algorithm enables better search for RNA-binding peptides: Redesigned λ N peptide binds boxB RNA

9. A platform for actively loading cargo RNA to elucidate limiting steps in EV-mediated delivery

10. Transforming growth factor-beta 1 delivery from microporous scaffolds decreases inflammation post-implant and enhances function of transplanted islets

11. Macrophages employ quorum licensing to regulate collective activation

12. Enrichment of Extracellular Vesicle Subpopulations Via Affinity Chromatography

13. Advances, challenges, and opportunities in extracellular RNA biology: insights from the NIH exRNA Strategic Workshop

14. Extended Concerted Rotation Technique Enhances the Sampling Efficiency of the Computational Peptide-Design Algorithm

15. Delivery of Biomolecules via Extracellular Vesicles

16. Reframing cell therapy for cancer

17. Predicting the Dynamics and Heterogeneity of Genomic DNA Content within Bacterial Populations across Variable Growth Regimes

18. Engineering cell-based therapies to interface robustly with host physiology

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