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Age misreporting is a common phenomenon in Demographic and Health Surveys, and there are numerous reasons for this. The trend and pattern of disparity in age heaping vary between countries. The present study assesses age heaping in the selected South Asian countries of Afghanistan, India, Nepal, Bangladesh and Pakistan using data from the most recent round of the Demographic and Health Survey. The respondent sample sizes were 203,703 for Afghanistan, 2,869,043 for India, 49,064 for Nepal, 81,618 for Bangladesh and 100,868 for Pakistan. Age heaping was assessed by respondent’s age, education level, sex and level of education. Whipple’s index was calculated to assess systematic heaping on certain ages as a result of digit preference. Bangladesh, Afghanistan and India showed stronger preference for ages ending with the digits ‘0’ and ‘5’ compared with Pakistan and Nepal among uneducated respondents. On the other hand, strong avoidance of ages ending in the digits ‘1’, ‘4’ and ‘9’ was observed in Bangladesh, Afghanistan and India. However, urban–rural place of residence was not found to be associated with digit preference in the study countries. Among males, age misreporting with the final digits ‘0’ and ‘5’ was highest in Bangladesh, followed by Afghanistan and India, and Nepal showed the least displacement. Strong digit preference and avoidance, and upper age displacement, were witnessed in the surveys conducted in Bangladesh, Afghanistan and India on the parameters of sex and education level. Innovative methods of data collection with the measurement and minimization of errors using statistical techniques should be used to ensure accuracy of age data.

Background In India, it was reported previously about varying prevalence of asthma and chronic bronchitis among leather tannery workers with moderate to high exposures at the workplace to be significantly associated with asthma. This study intended to estimate the prevalence of asthma, tuberculosis, and chronic bronchitis among leather tannery workers and to identify the risk factors associated with it. Data and Methods The data used in this study were collected through a cross-sectional household survey of 284 male tannery workers in the Jajmau area of Kanpur city in the state of Uttar Pradesh, during January–June 2015. A binary logistic regression analysis was performed to identify the factors associated with respiratory symptoms. Results The prevalence Asthma and Chronic Bronchitis among Tannery workers was 12.3% and 11.6% which is higher as compared to non-tannery workers. The findings revealed that the prevalence of symptoms suggestive of asthma, tuberculosis, and chronic bronchitis among the tannery workers was higher compared to non-tannery workers. The study revealed that long time tannery working harms health, as tannery workers are more likely to be suffering from asthma and chronic bronchitis who worked above 11 years in the tannery (p Conclusion The study concludes that age, education, media exposure, working hours in the tannery, type of work engagement within tannery occupation, and exposure to chemicals are the major risk factors for asthma, tuberculosis, and chronic bronchitis among the male tannery workers. Specific health insurance facilities should be provided, such as the Employee's State Insurance Scheme (ESIS), from the day a person begins work in a tannery.

Occupational health covers all aspects of health and safety in the workplace and has a strong focus on primary prevention of hazards. The objective of the study was to understand the extent of awareness about occupational health risks involved in tannery occupation and adopted preventive measures by the tannery workers of Kanpur, India. Information for the present research was strained from a cross-sectional household study of tannery workers in the Jajmau area of Kanpur. The survey was piloted through the period January–June 2015, and 284 samples were collected. The prevalence of awareness of tannery work is very hazardous in nature varies from 73–93% among the tannery workers. Tannery workers having a middle-school level of education were 3.01 times more likely to be aware of the hazards as compared to the illiterate workers. Tannery workers aged 36 and above were less likely to aware of a hazardous work environment. Further, tannery workers who belong to the younger cohort (16–24 years) reported a higher awareness of respiratory problems (38%), skin complaints (59%), and gastrointestinal issues (21%) than those aged 36 years and above. About one-third of Beam house workers (33%) and over a quarter (26%) of the wet finishing had moderate to high dermal contact with the chemicals. The study’s outcomes give a clear indication of the effect of the workstation environment on the health status of workers and require the use of adequate measures to improve the facilities and thereby the health status of tannery workers.

In recent decades, air pollution has become a real threat to the lives and health of populations around the world. Today, about 92% of the world’s population lives in areas with low air quality standards. In India, in particular, air pollution is one of the main causes of respiratory and allergic diseases, asthma, chronic obstructive pulmonary disease, pneumonia, and even tuberculosis. The purpose of this study is to analyze the extent of the spread of respiratory diseases in people living near the leather manufacturing industry in Jammu, Kanpur, India. The source of information is a cross-sectoral survey of male workers from the Jammu area, for which a three-stage sampling model is used. The study area selected areas of Bujiat, Motinagar, and Asharfabad because of the high concentration of the population employed in leather processing plants. During the study, the authors used one- and two-dimensional statistics. The study showed that there are no major benefits of civilization in the study areas: housing, water, hygiene and sanitation, waste treatment, etc. In the last 12 months, it was found that 11% of the population in the aforementioned territory experienced symptoms such as wheezing or wheezing at any time of the day, ie permanently, and another 9% of the population were waking up from chest tightness in the previous 12 months. During the survey period, 10% of the respondents had coughing sputum at least three months before the day or night. The rapid spread of various respiratory diseases may be associated with higher levels of air pollution. The article presents the recommendations of the authors on adherence to the principles of fair industrial activity within the framework of corporate social responsibility and the promotion of sustainable development of territories. Keywords: living environment, morbidity, respiratory health, workers.

Persisters of Mycobacterium tuberculosis (Mtb) that fail to form colonies on agar media when de-stressed are termed as differentially detectable (DD) persisters. Since in the host, Mtb primarily survives by utilizing lipids, we used a long-term lipid diet model to induce DD persisters of M. tuberculosis. Persisters were induced by replacing the dextrose-containing medium with one containing fatty acids instead of dextrose (FAM). After 2, 4 or 6 weeks, CFU and most probable number assays were performed; the difference between the two gave an estimate of DD persisters. Since rifampicin has been shown to induce formation of DD persisters in vitro, one set of FAM cultures were also given short-term rifampicin stress after 2, 4 or 6 weeks. Fraction of DD persisters increased with time and rifampicin treatment enhanced the effect of fatty acids, at 2 and 4 weeks. At six weeks, even in the absence of rifampicin, ∼95% population were DD persisters. The DD persisters were vulnerable to drugs interfering with bacterial respiration such as thioridazine, bedaquiline and clofazimine. The study indicates potential formation of DD persisters of Mtb in a lipid-rich microenvironment in the host even before antibiotic therapy.

There is a well-established association between tobacco consumption with asthma and chronic bronchitis (CB). This study aimed at estimating the prevalence of tobacco consumption and its association with asthma and CB in Kanpur, Uttar Pradesh, India. A cross-sectional household survey of 573 males was conducted during January–June 2015 in the Jajmau area of Kanpur, Uttar Pradesh, India. The questionnaire was designed to collect information on self-reported symptoms pertaining to asthma and CB, which were considered as response variables for the study. More than one-third of the respondents (36%) smoked tobacco and 44% consumed smokeless tobacco. Men who were aged 35 years and above were more prone to CB, with odds ratios (ORs) of 2.08 in model 1 and 1.84 in model 2. The prevalence of CB is higher among those from the Scheduled Castes and Scheduled Tribes (12.4%). People consuming any form of tobacco are more likely to get CB (OR = 5.22) than their counterparts who do not consume tobacco. The chances of getting asthma was higher among those who consumed any form of smokeless tobacco (OR = 1.34) and those who consume any form of tobacco (OR = 2.30) in model 2. Our study found a significant association between tobacco consumption (smoking and use of smokeless tobacco) with asthma and CB and the predictors that affect the pattern of tobacco consumption, such as respondents’ age, education level, caste, level of exposure to the media, and standard of living index.

India is greatly afflicted by sinusitis, which is a condition that involves inflaming sinuses (the air cavities in the nasal passage) in your nose, according to the National Institute of Allergy and Infectious Diseases (NIAID). The study&rsquo, s objective was to evaluate the prevalence and risk factors of sinus and nasal allergies among tannery workers of Kanpur city. The study has used primary datasets obtained from a cross-sectional household study of tannery workers from the Jajmau area of Kanpur in northern India, which was conducted during January&ndash, June 2015 as part of a doctoral program. The study covered 286 tannery workers from the study area. Bivariate and logistic regression analysis was used to study the association between outcome variables (self-reported prevalence of sinus and nasal allergies) and predictor variables (socioeconomic and work-related characteristics). Results portray that a higher proportion of the tannery workers belong to economically and socially backward classes. Overall, 13.4 and 12.3% of sinus and nasal allergy prevalence have been reported by tannery workers, whereas tannery workers from the oldest age group were those who mainly suffered. A study found that the severity of nasal and sinus allergies increases with the increasing age and work duration in the tannery. Workers with low exposure to airborne dust were significantly more likely to develop sinus problems (OR = 4.16, p &lt, 0.05) than those without exposure. Those tannery workers suffering from nasal allergy were more prone to develop sinus problems than those who were not suffering from nasal allergy. The risk factors responsible for these health hazards can be eliminated by improving the overall working conditions and ensuring necessary protective regulations for the tannery workers.

Purpose: Treatment-seeking behaviors and economic burden because of health expenditure are widely discussed issues in India, and more so in recent times. The aim of this study is to identify health problems of tannery workers and their treatment-seeking behavior and their health expenditure. Data and Methods: The primary data used in this article were collected through a cross-sectional household survey of 284 male tannery workers in the Jajmau area of Kanpur city in the state of Uttar Pradesh, during January–June 2015. Results: Findings of the study revealed that around 36% of the tannery workers and 42% of non-tannery workers received treatment as outpatients in government/municipal hospital in the first spell of treatment. The secondary source of treatment was pharmacy/drug stores for 30% of the tannery workers and 24% of the non-tannery workers, an indication that a substantial proportion takes treatment without consulting a qualified medical practitioner; it also highlights that almost one-third of the tannery and non-tannery workers visited private health facility despite poor economic condition. It is evident that a substantial proportion of tannery and non-tannery workers are visiting private/non-governmental organization/trust hospital despite their poor financial situation. Conclusion: There is an urgent need to reinstate people's faith in public health facilities by developing professionalism, integrity, and accountability among different levels of health functionaries and frontline workers with the support of credible, transparent, and responsible regulatory environment.

Background Tuberculosis (TB) has been a major health problem globally since ages, and even today, it is a major cause of morbidity in millions of people each year. In 2015 alone, TB accounted for about 1.4 million deaths globally, with India carrying the biggest burden of the disease. The physical environment of the household, an individual living in, has a significant influence on the incidence of TB. Thus, an understanding of the socio-economic, demographic and environmental factors that individuals are exposed to is of importance. The objective of present study is to examine the association of household environment with the prevalence of Tuberculosis in India. Methods The study utilizes data from the fourth round of National Family Health Survey (NFHS-4), 2015-16, which was collected from self-reported information pertaining to Tuberculosis in the household questionnaire. The specific question was, “Does any usual resident of your household suffer from tuberculosis?” the response to which helped in the detection of Tuberculosis. Binary Logistic regression was performed from which appropriate inferences are drawn on the association of household environment with Tuberculosis. Results Prevalence of TB was found to be the highest among elderly people (0.9%), no education (0.4%) and people belonging to the poorest wealth quintile (0.53%). Family members who were regularly (daily) exposed to smoke (second-hand smoke) inside the house were more prone to getting tuberculosis (OR = 1.49; CI = 1.39-1.61) as compared with households where people do not smoke inside the house. Further, households having a finished wall (OR = 0.7; CI = 0.6-0.8) are less likely to get TB than the households with mud walls. Households that shared their toilets with other households are more likely to get hold of Tuberculosis (OR = 1.2; CI = 1.1-1.4). Conclusions Results strongly suggest that a contaminated household environment increases the risk of tuberculosis in India. There are multiple risk factors that are strongly associated with Tuberculosis: smoke inside house, type of cooking fuel, separate kitchen, floor, roofing and wall material, number of persons sleeping in a room, sharing toilet and potable water with other households; and individual characteristics such as age, sex, educational attainment, marital status, place of residence and wealth index. Electronic supplementary material The online version of this article (10.1186/s12890-018-0627-3) contains supplementary material, which is available to authorized users.

The 2014-2019 Prevention Research Centers (PRC) Program Funding Opportunity Announcement stated that "all applicants will be expected to collaborate with CDC to collect data to be able to perform cost analysis." For the first time in the 30-year history of the PRC Program, a cost indicator was included in the PRC Program Evaluation and a cost analysis (CA) instrument developed. The PRC-CA instrument systematically collects data on the cost of the PRC core research project to eventually answer the CDC PRC Program Evaluation question: "To what extent do investments in PRCs support the scalability, sustainability, and effectiveness of the outcomes resulting from community-engaged efforts to improve public health?" The objective of this article is to briefly describe the development of the PRC-CA instrument. Data obtained from the PRC-CA instrument can be used to generate cost summaries to inform decision making within the PRC Program and each individual PRC.

Background The occupation of waste-picking characterised as 3Ds – dangerous, drudgery and demanding. In this context, the study aimed to assess occupational morbidities among the waste-pickers and attempts to identify potential individual level risk factors enhancing health risks. Additionally, economic burden of morbidities has been assessed. Methods The burden of the morbidities was assessed and compared with a comparison group through a cross-sectional survey. Waste-pickers (n = 200) and a comparison group (n = 103) working for at least a year were randomly selected from the communities living on the edge of the Deonar dumping site. The difference in the prevalence of morbidities was tested using the chi-square test. The effect of waste picking resulting the development of morbidities was assessed using the propensity score matching (PSM) method. A multivariate logistic regression model was employed to identify the individual risk factors. T-test has been employed in order to analyse the difference in health care expenditure between waste pickers and non-waste pickers. Results The prevalence of morbidities was significantly higher among the waste-pickers, particularly for injuries (75%), respiratory illness (28%), eye infection (29%), and stomach problems (32%), compared to the comparison group (17%, 15%, 18%, and 19% respectively). The results of the PSM method highlighted that waste-picking raised the risk of morbidity for injuries (62%) and respiratory illness (13%). Results of logistic regression suggest that low level of hygiene practices [household cleanliness (OR = 3.23, p

Triacylglycerol (TAG) is important to mycobacteria both as cell envelope component and energy reservoir. Mycobacterium tuberculosis (Mtb) genome encodes at least 15 putative TAG synthase (tgs)s. We report that one of these genes, Rv3371, specific to pathogenic mycobacteria, when expressed in M. smegmatis leads to modifications in colony morphotype, bacterial architecture, cell surface properties and elevated TAG levels. Rv3371 was found to largely localize in the cell membrane. The Rv3371 promoter is minimally active during exponential growth in vitro, however, is up-regulated under stationary phase, hypoxia, nutrient starvation, nitrosative stress, low iron, in IFN-γ activated macrophages and infected mice. The low iron-induced expression of Rv3371 is likely due to the de-repression by Rv1404, which is probably activated by ideR. An Rv3371 deletion mutant of Mtb showed impaired non-replicating persistence in vitro and altered sensitivity to anti-mycobacterial drugs. In low iron medium, the Rv3371 deletion mutant showed reduced formation of TAG containing extracellular vesicles. Therefore Rv3371 is likely involved in Mtb growth arrest and cell wall alterations during persistence.

Background: Low Back Trouble (LBT) is very common among tannery workers, it occurs due to the bend posture of low back during the material transfer. Aim: This paper analyzes the prevalence of the self-reported LBT, its intensity and the potential risk factors among male tannery workers in Kanpur, India. Methods: Data for the study were obtained from a cross-sectional household survey conducted during the period January-June, 2015. The study was conducted in the Jajmau area of Kanpur and interviewed 284 tannery workers selected using scientifically developed study design using probability sampling approach. Univariate and bivariate analyses were used to assess the prevalence and intensity of LBT. Logistic regression analysis was used to identify the potential risk factors for contracting LBT. Results: Tannery workers aged 35 years and above had higher prevalence of LBT (57%). A significant association was observed between long working 11-12 h and the prevalence was (68%) of LBT. Among the workers aged 35+years, about a sixth (16%) reported daily recurrence of pain, and about a fifth (19%) experienced pain more than 10 times in the last 12 months. Tannery workers who were injured at work in the last 12 months was 2.09 and 2.42 times more likely to get LBT in Model-II and III. The adjusted effect of LBT was 1.8 times higher among tannery workers had severe mental health disorders. Conclusions: The results reveal statistically significant association of LBT with age of tannery workers, educational attainments, type of job contract, type of work, daily working hours, manual loading and unloading, workplace injury in last 12 months and mental health disorders.

Background The purpose of this study was to test the reliability, validity and factor structure of GHQ-12 questionnaire on male tannery workers of India. We have tested three different factor models of the GHQ-12. Methods This paper used primary data obtained from a cross-sectional household study of tannery workers from Jajmau area of the city of Kanpur in northern India, which was conducted during January–June, 2015, as part of a doctoral program. The study covered 286 tannery workers from the study area. An interview schedule containing GHQ-12 was used for tannery workers who had completed at least 1 year at their present occupation preceding the survey. To test reliability, Cronbach’s alpha test was used. The convergent test was used for validity. Confirmatory factor analysis was used to compare three factor structures for the GHQ-12. Results A total of 286 samples were analyzed in this study. The mean age of the tannery workers in this study was 38 years (SD = 1.42). We found the alpha coefficient to be 0.93 for the complete sample. The value of alpha represents the acceptable internal consistency for all the groups. Each item of scale showed almost the same internal consistency of 0.93 for the male tannery workers. The correlation between factor 1 (Anxiety and Depression) and factor 2 (Social Dysfunction) was 0.92. The correlation between factor 1 (Anxiety and Depression) and factor 3 (Loss of confidence) was the highest 0.98. Comparative fit index (CFI) estimate best-fitted for model-III that gave the CFI value 0.97. The SRMR indicator gave the lowest value 0.031 for the model-III. Conclusions The findings suggest that the Hindi version of GHQ-12 is a reliable and valid tool for measuring psychological distress in male tannery workers of Kanpur city, India. Study found that the model proposed by the Graetz was the best fitted model for the data.