1. Comprehensive chemical study on different organs of cultivated and wild Sarcandra glabra using ultra-high performance liquid chromatography time-of-flight mass spectrometry (UHPLC-TOF-MS)
- Author
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Jiang Zhi-Hong, Che Kai-Si, Chen Da-Xin, Zhang Wei, LU Jing-Guang, Zhong Ming, Wang Cai-Yun, and Wang Jing-Rong
- Subjects
Plant Stems ,010405 organic chemistry ,Phytochemicals ,General Medicine ,Biology ,Plant Roots ,01 natural sciences ,Mass Spectrometry ,0104 chemical sciences ,Plant Leaves ,Magnoliopsida ,03 medical and health sciences ,Horticulture ,0302 clinical medicine ,Complementary and alternative medicine ,030220 oncology & carcinogenesis ,Chemical constituents ,Drug Discovery ,Ultra high performance ,Time-of-flight mass spectrometry ,Chromatography, High Pressure Liquid ,Sarcandra glabra - Abstract
To illuminate the similarities and differences between wild and cultivated Sarcandra glabra (S. glabra), we performed a comprehensively study on 26 batches of cultivated S. glabra and 2 batches of wild S. glabra. Chemical constituents and distribution characteristics of roots, stems and leaves in both wild and cultivated S. glabra were investigated through UHPLC-TOF-MS method. The result revealed that there were significant differences between roots, stems and leaves in S. glabra. And the chemical contents in the root part were less or even absence than those in leaf and stem, which suggested the root organ could be excluded as medicine. Meanwhile, the chemical contents of stems and leaves in cultivated S. glabra was sightly higher than that of wild samples. Therefore, cultivated S. glabra may have a high potential for substitution of wild S. glabra without affecting its pharmaceutical properties. In summary, our study could provide important information to the molecular basis for quality control of S. glabra.
- Published
- 2021