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Start Over Author "Tong-Jian Cui" Topic 02 engineering and technology
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1. Sodalite-type metal-organic zeolite with uncoordinated N-sites as potential anticancer drug 5-fluorouracil (5-FU) delivery platform

Author

Guishan Lin, Jing-Bo Chen, Fei Wang, Tong-Jian Cui, and Jian Zhang

Subjects
Fast speed, Chemistry, 02 engineering and technology, engineering.material, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, Anticancer drug, Combinatorial chemistry, 0104 chemical sciences, Inorganic Chemistry, chemistry.chemical_compound, Type metal, Fluorouracil, Materials Chemistry, medicine, engineering, Sodalite, Physical and Theoretical Chemistry, 0210 nano-technology, Zeolite, medicine.drug
Abstract

In this work, a SOD type metal-organic zeolite ZTIF-1 was used to entrap the anticancer drug 5-fluorouracil (5-FU). This material exhibited high capability for 5-FU with fast speed owing to its large surface area and uncoordinated N-heteroatom sites. These results suggest that ZTIF-1 could be a valuable platform for delivery of anti-cancer agents.

Published
2019

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