1. Synthesis and Herbicidal Activity Against Buffelgrass (Cenchrus ciliaris) of (±)-3-deoxyradicinin
- Author
-
Marco Masi, Maria Sabrina Ciccone, Antonio Evidente, Fabrizio Freda, Patrizia Scafato, Giulia Marsico, Massimo Cristofaro, Stefano Superchi, Marsico, G., Ciccone, M. S., Masi, M., Freda, F., Cristofaro, M., Evidente, A., Superchi, S., and Scafato, P.
- Subjects
0106 biological sciences ,buffelgrass ,(±)-3-deoxyradicinin ,Pharmaceutical Science ,01 natural sciences ,Article ,Deoxyradicinin ,Analytical Chemistry ,lcsh:QD241-441 ,phytotoxins ,Phytotoxin ,lcsh:Organic chemistry ,Cenchrus ciliaris ,bioherbicides ,Drug Discovery ,Physical and Theoretical Chemistry ,Buffelgra ,biology ,Herbicides ,010405 organic chemistry ,Cenchrus ,Organic Chemistry ,biology.organism_classification ,0104 chemical sciences ,radicinin ,Agronomy ,Pyrones ,Bioherbicides ,Buffelgrass ,Phytotoxins ,Radicinin ,Chemistry (miscellaneous) ,Molecular Medicine ,Phytotoxicity ,Bioherbicide ,010606 plant biology & botany - Abstract
A novel synthetic strategy for obtainment of (±, )-3-deoxyradicinin (2) is reported. This synthetic methodology is more efficient than those previously reported in the literature and also shows higher versatility towards the introduction of different side-chains at both C-7 and C-2. The obtained compound (±, )-2 shows phytotoxicity against the grass-weed buffelgrass comparable to that of the natural phytotoxin radicinin (1). Therefore, (±, )-2 can constitute a more practical synthetic alternative to 1 as bioherbicide for buffelgrass control.
- Published
- 2019
- Full Text
- View/download PDF