1. Phenolic glycosides from the stems of Homalium stenophyllum
- Author
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Si-Yu Zhao, Qi Zhou, Meng Bai, Xu-Hua Nong, Chang-Ri Han, Xiao-Ping Song, Shou-Yuan Wu, and Guang-Ying Chen
- Subjects
Salicaceae ,Phytochemicals ,Anti-Inflammatory Agents ,01 natural sciences ,03 medical and health sciences ,Hydrolysis ,0302 clinical medicine ,Phenols ,Drug Discovery ,Organic chemistry ,Glycosides ,No production ,Homalium ,chemistry.chemical_classification ,Molecular Structure ,Plant Stems ,biology ,010405 organic chemistry ,Macrophages ,Glycoside ,General Medicine ,biology.organism_classification ,Mass spectrometric ,0104 chemical sciences ,Complementary and alternative medicine ,chemistry ,Phytochemical ,030220 oncology & carcinogenesis - Abstract
The phytochemical investigation of the stems of Homalium stenophyllum afforded seven new phenolic glycosides (1−5 and 8−9) and two known compounds (6 and 7). Their structures were elucidated by comprehensive analyses of NMR spectroscopic, mass spectrometric data and chemical hydrolysis. Additionally, their anti-inflammatory activities against the NO production in LPS-induced macrophages were evaluated.
- Published
- 2021
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