1. On chip optofluidic low‐pressure monitoring device
- Author
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Shreyas Bangalore Subramanya, Abhijit Roy, Shoorashetty Manohar Rudresh, and Venkataraman Venkatakrishnan
- Subjects
Materials science ,Microfluidics ,General Physics and Astronomy ,01 natural sciences ,General Biochemistry, Genetics and Molecular Biology ,Optofluidics ,010309 optics ,chemistry.chemical_compound ,Dove prism ,Lab-On-A-Chip Devices ,0103 physical sciences ,Humans ,General Materials Science ,Total internal reflection ,Polydimethylsiloxane ,business.industry ,010401 analytical chemistry ,General Engineering ,General Chemistry ,Microfluidic Analytical Techniques ,Pressure sensor ,0104 chemical sciences ,chemistry ,Printing, Three-Dimensional ,Oil immersion ,Optoelectronics ,Ray tracing (graphics) ,business - Abstract
We present an on chip optofluidic surface deformable liquid Dove prism (LDP) based low-fluid flow pressure monitoring device. The unique design of the device in combination with liquid and soft solid enabled by the total internal reflection of light makes the sensor highly sensitive and compatible with the integration of a microfluidic and/or Lab-on-a-chip device. A layer-by-layer soft lithographic (LSL) and 3D printing technique are exploited to make the device. We have used Polydimethylsiloxane (PDMS) as the layer material and two variety of liquids (a) immersion oil (IO) and (b) di-iodomethane (DI) as refracting medium to construct the LDP sensor. Optical ray tracing simulation is performed to optimize the sensor. The pressure sensor shows sensitivity as high as ±28.5 mV per 50 Pa pressure with an error ± 2.5 mV and repeatability of ~99.56% at full scale. We have shown the applicability of the sensor by capturing and analyzing respiratory pressure signals of some human subjects at numerous conditions.
- Published
- 2020
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