1. Smart home-based prediction of multi-domainsymptoms related to Alzheimer's Disease
- Author
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Ane Alberdi, Maureen Schmitter-Edgecombe, Asier Aztiria, Diane J. Cook, Adrian Basarab, Maitane Barrenechea, Alyssa Weakley, Mondragon Unibertsitatea, Washington State University (WSU), CoMputational imagINg anD viSion (IRIT-MINDS), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Université Toulouse III - Paul Sabatier (UT3), Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse - Jean Jaurès - UT2J (FRANCE), Université Toulouse 1 Capitole - UT1 (FRANCE), Mondragon Unibertsitatea (SPAIN), Washington State University - WSU (USA), Institut de Recherche en Informatique de Toulouse - IRIT (Toulouse, France), and Institut National Polytechnique de Toulouse - INPT (FRANCE)
- Subjects
Male ,Computer science ,Disease ,computer.software_genre ,01 natural sciences ,0302 clinical medicine ,Health Information Management ,Multimodal symptoms ,Human Activities ,Aged, 80 and over ,Signal Processing, Computer-Assisted ,Cognition ,Regression analysis ,Modélisation et simulation ,Automatic assessment ,Home Care Services ,Computer Science Applications ,Older adults ,Female ,Alzheimer’s disease ,Algorithms ,Biotechnology ,Monitoring, Ambulatory ,Médecine humaine et pathologie ,Feature selection ,Machine learning ,Article ,Activity recognition ,03 medical and health sciences ,Alzheimer Disease ,medicine ,Humans ,Dementia ,Electrical and Electronic Engineering ,Aged ,Behavior ,business.industry ,Smart homes ,010401 analytical chemistry ,medicine.disease ,[INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation ,0104 chemical sciences ,Mood ,Informatics ,Artificial intelligence ,business ,computer ,030217 neurology & neurosurgery ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
As members of an increasingly aging society, one of our major priorities is to develop tools to detect the earliest stage of age-related disorders such as Alzheimer's Disease (AD). The goal of this paper is to evaluate the possibility of using unobtrusively collected activity-aware smart home behavior data to detect the multimodal symptoms that are often found to be impaired in AD. After gathering longitudinal smart home data for 29 older adults over an average duration of $>$ 2 years, we automatically labeled the data with corresponding activity classes and extracted time-series statistics containing ten behavioral features. Mobility, cognition, and mood were evaluated every six months. Using these data, we created regression models to predict symptoms as measured by the tests and a feature selection analysis was performed. Classification models were built to detect reliable absolute changes in the scores predicting symptoms and SmoteBOOST and wRACOG algorithms were used to overcome class imbalance where needed. Results show that all mobility, cognition, and depression symptoms can be predicted from activity-aware smart home data. Similarly, these data can be effectively used to predict reliable changes in mobility and memory skills. Results also suggest that not all behavioral features contribute equally to the prediction of every symptom. Future work therefore can improve model sensitivity by including additional longitudinal data and by further improving strategies to extract relevant features and address class imbalance. The results presented herein contribute toward the development of an early change detection system based on smart home technology.
- Published
- 2018
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