1. Novel N-doped carbon dots prepared via citric acid and benzoylurea by green synthesis for high selectivity Fe(III) sensing and imaging in living cells
- Author
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Feishi Shan, Zhouyu Wang, Hui Yang, Haoyu Xia, Xiangyan Xie, Fu Lijuan, Yuanyuan Zhang, Xiaoqi Yu, and Qian Zhou
- Subjects
Detection limit ,Quenching ,Absorption spectroscopy ,Benzoylurea ,Metal ions in aqueous solution ,010401 analytical chemistry ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Fluorescence ,0104 chemical sciences ,Analytical Chemistry ,chemistry.chemical_compound ,chemistry ,medicine ,0210 nano-technology ,Selectivity ,Citric acid ,Spectroscopy ,medicine.drug ,Nuclear chemistry - Abstract
A novel N-doped carbon dots (N-CDs (CA + BU)) derived from citric acid (CA) and benzoylurea (BU) were prepared by a green, simple and environment friendly synthetic method free of solvents. The N-CDs (CA + BU) is found to be served as highly selectivity PL sensor for Fe(III) detection. Systematic investigation showed that only Fe(III) can quench the PL of N-CDs (CA + BU) among the test metal ions. The N-CDs (CA + BU) could serve as a sensitive “turn-off” fluorescent sensor for Fe(III) and the detection limit was as low as 1.1 μM. In addition, the mechanism of Fe(III) quenching to the PL of N-CDs (CA + BU) was thoroughly studied. The absorption spectrum of N-CDs (CA + BU) with or without Fe(III), the influence of temperature on PL quenching and the PL lifetime were studied and discussed. The results confirmed that the quenching belongs to dynamic quenching. Finally, PL imaging and intracellular Fe(III) sensing were realized in A549 cells.
- Published
- 2021