1. Endocrine disrupting effects of copper and cadmium in the oocytes of the Antarctic Emerald rockcod Trematomus bernacchii
- Author
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Emanuela Califano, Mariana Di Lorenzo, Raffaele Panzuto, Chiara Maria Motta, Palma Simoniello, Vincenzo Migliaccio, Gianfranco Santovito, Motta, CHIARA MARIA, Simoniello, Palma, DI LORENZO, Mariana, Migliaccio, Vincenzo, Panzuto, Raffaele, Califano, Emanuela, and Santovito, Gianfranco
- Subjects
medicine.medical_specialty ,Environmental Engineering ,Carbohydrate composition ,carbohydrate composition.Estrogen receptors.Heavy metals, contentLectin staining,Oocyte degeneration,Ovarian morphology,PAS staining,Progesterone receptors ,Health, Toxicology and Mutagenesis ,Lectin staining ,0208 environmental biotechnology ,Antarctic Regions ,Estrogen receptor ,chemistry.chemical_element ,Estrogen receptors ,02 engineering and technology ,contentLectin staining ,010501 environmental sciences ,Progesterone receptors ,01 natural sciences ,Internal medicine ,Trematomus ,medicine ,Animals ,Environmental Chemistry ,Endocrine system ,Heavy metals content ,Oocyte degeneration ,Ovarian morphology ,PAS staining ,Receptor ,0105 earth and related environmental sciences ,Progesterone receptors, Estrogen receptors, Carbohydrate composition PAS staining, Lectin staining, Oocyte degeneration, Heavy metals content, Ovarian morphology ,Cadmium ,biology ,Chemistry ,Public Health, Environmental and Occupational Health ,General Medicine ,General Chemistry ,Oocyte ,biology.organism_classification ,Pollution ,Perciformes ,020801 environmental engineering ,medicine.anatomical_structure ,Endocrinology ,Emerald rockcod ,Cytoplasm ,Oocytes ,carbohydrate composition.Estrogen receptors.Heavy metals ,Copper - Abstract
Antarctica has long been considered a continent free from anthropic interference. Unfortunately, recent evidence indicate that metal contamination has gone so far and that its effects are still unknown. For this reason, in the present work, the potential endocrine disrupting effect of two highly polluting metals, copper and cadmium, were examined in the Antarctic teleost Trematomus bernacchii. After a 10 days waterborne exposure, ovarian metal uptake was determined by atomic absorption; in parallel, classical histological approaches were adopted to determine the effects on oocyte morphology, carbohydrate composition and presence and localization of progesterone and estrogen receptors. Results show that both metals induce oocyte degeneration in about one third of the previtellogenic oocytes, no matter the stage of development. In apparently healthy oocytes, changes in cytoplasm, cortical alveoli and/or chorion carbohydrates composition are observed. Cadmium but not copper also induces significant changes in the localization of progesterone and beta-estrogen receptors, a result that well correlates with the observed increase in ovarian metals concentrations. In conclusion, the acute modifications detected are suggestive of a significantly impaired fecundity and of a marked endocrine disrupting effects of copper and cadmium in this teleost species.
- Published
- 2021
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