Search

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 探讨BMI与胃癌临床病理参数、手术并发症及预后的关系。方法 行根治手术治疗的胃癌患者466例,根据术前BMI将患者分为体重过低组(BMI<18.5)64例、正常体重组(BMI 18.5~24.0)256例、超重组(BMI≥24.0)126例。收集三组患者年龄、性别、术前血红蛋白水平、术前白蛋白水平、术后病理分化程度、肿瘤最大径、肿瘤浸润深度、淋巴结清扫数目、淋巴结转移情况、TNM分期、手术并发症、围手术期死亡及预后情况等资料,并进行分析。结果三组淋巴结转移分期(N分期)及转移淋巴结数目相比,P均<0.05。胃癌患者术前BMI与术前血清白蛋白水平呈正相关关系(r=0.120,P=0.019),与手术清扫淋巴结数目呈负相关关系(r=-0.168,P=0.001),与转移淋巴结数目呈正相关关系(r=0.163,P=0.001)。466例患者中80例(17.9%)出现术后并发症,体重过低组、正常体重组、超重组发生术后并发症的例数分别为10、40、30例,三组相比,P均>0.05。8例患者围手术期死亡,其中体重过低组1例、正常体重组4例、超重组3例,三组相比,P均>0.05。体重过低组、正常体重组、超重组5年生存率分别为30.6%、43.7%、26.1%,三组相比,P均<0.05。单因素分析结果显示,BMI与患者生存相关;多因素分析结果显示,BMI并非胃癌的独立预后因素。结论术前BMI与胃癌患者血清白蛋白水平、手术清扫淋巴结数目及转移淋巴结数目有关。胃癌患者术前BMI与手术并发症无明显关系,但与胃癌患者预后有一定关系,BMI过高或过低者预后较BMI正常者差。 [ABSTRACT FROM AUTHOR]