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Parkinson’s disease(PD), known medically as "primary paralysis paralysis," also known as "Parkinson’s disease," is a central nervous system degenerative disorder mainly caused by the presence of "substantia nigra " In dopamine(DA) neurons pathological changes after the reduction of dopamine synthesis, and its function antagonism of acetylcholine inhibition decreased, the excitement of acetylcholine relatively enhanced. The result of the imbalance between the two appeared "paralysis of paralysis". This review firstly summarizes the current clinical medicine for western medicine in the direction of the pathogenesis of PD(including levodopa, DA degrading enzyme inhibitors, DA receptor agonists, anticholinergic drugs), gene therapy targets, surgery(DBS) and physical therapy, and also introduces the treatment of traditional Chinese medicine and acupuncture and moxibustion treatment from the point of view of traditional Chinese medicine. PD has a serious impact on patients’ daily life and physical and mental health, we hope that through this review, we will provide broader clinical ideas and better solutions for PD comprehensive treatment. [ABSTRACT FROM AUTHOR]

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