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Start Over Author "Paris, Cédric" Topic [chim]chemical sciences
9 results on '"Paris, Cédric"'

1. Application in Nutrition: Mineral-Binding

Author

El Hajj, Sarah, Sepulveda-Rincon, Tatiana, Paris, Cédric, Giraud, Tristan, Csire, Gizella, Stefan, Loic, Selmeczi, Katalin, Girardet, Jean-Michel, Desobry, Stéphane, Muhr, Laurence, Gaucher, Caroline, Canabady-Rochelle, Laetitia, Laboratoire Réactions et Génie des Procédés (LRGP), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Cibles thérapeutiques, formulation et expertise pré-clinique du médicament (CITHEFOR), Université de Lorraine (UL), Laboratoire d'Ingénierie des Biomolécules (LIBio), Laboratoire de Chimie Physique Macromoléculaire (LCPM), Laboratoire Lorrain de Chimie Moléculaire (L2CM), Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL), Institut für Angewandte Materialien (IAM), Karlsruher Institut für Technologie (KIT), Fidel Toldra, and Jianping Wu

Subjects
[SPI]Engineering Sciences [physics], [SDV]Life Sciences [q-bio], [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2021

2. Optimization of a LCMS Method for screening of iron-chelating peptides by differential mass spectrometry analysis

Author

Paris, Cédric, Selmeczi, Katalin, Chaimbault, Patrick, DESOBRY, Stephane, Canabady-Rochelle, Laetitia, Laboratoire Réactions et Génie des Procédés (LRGP), and Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)

Subjects
[SPI]Engineering Sciences [physics], [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2020

3. Metal-chelating peptides in hydrolysates: production, characterization and screening

Author

hajj, El, Cakir-Kiefer, Céline, Loic, Stefan, Pontvianne, Steve, Arnoux, Philippe, Paris, Cédric, Muhr, L., Selmeczi, Katalin, DESOBRY, Stephane, Boschi-Muller, Sandrine, Gaucher, Caroline, Canabady-Rochelle, Laetitia, Laboratoire Réactions et Génie des Procédés (LRGP), and Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)

Subjects
[SPI]Engineering Sciences [physics], [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2019

4. Iron(III)-chelating model peptides as bioinspired antioxidants

Author

Csire, Gizella, Paris, Cédric, Canabady-Rochelle, Laetitia, Loïc, Stefan, Selmeczi, Katalin, Laboratoire Réactions et Génie des Procédés (LRGP), and Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)

Subjects
[SPI]Engineering Sciences [physics], [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2019

5. IP-RPLC-MS Screening of iron(II) chelating peptides by differential analysis of mass spectra

Author

Paris, Cédric, Selmeczi, Katalin, Chaimbault, Patrick, DESOBRY, Stephane, Canabady-Rochelle, Laetitia, Laboratoire Réactions et Génie des Procédés (LRGP), and Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)

Subjects
[SPI]Engineering Sciences [physics], [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2019

6. Criblage IP-RPLC-MS de Peptides Chélateurs de Fer par Analyse Différentielle de Spectres de Masse

Author

Paris, Cédric, Selmeczi, Katalin, Chaimbault, P, DESOBRY, Stephane, Canabady-Rochelle, Laetitia, Laboratoire Réactions et Génie des Procédés (LRGP), and Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)

Subjects
[SPI]Engineering Sciences [physics], [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2019

7. Metal-chelating peptides in hydrolysates: a way to valorize protein-containing co-products in a bioeconomy strategy

Author

El Hajj, Sarah, Cakir-Kiefer, Céline, Stefan, Loïc, Pontvianne, Steve, Arnoux, Philippe, Paris, Cédric, Muhr, Laurence, Selmeczi, Katalin, DESOBRY, Stephane, Boschi-Muller, Sandrine, Gaucher, Caroline, Canabady-Rochelle, Laetitia, Laboratoire Réactions et Génie des Procédés (LRGP), and Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)

Subjects
[SPI]Engineering Sciences [physics], [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2019

8. Screening and Separation of Metal Chelating Peptides for Nutrition and Health Applications

Author

Boschi-Muller, Sandrine, Paris, Cédric, DESOBRY, Stephane, Selmeczi, Katalin, Chaimbault, Patrick, Pasc, Andreea, Cakir-Kiefer, Céline, Arrault, Axelle, Stefan, Loïc, Averlant-Petit, Marie Christine, Clarot, Igor, Leroy, Pierre, Gaucher, Caroline, Alem, Halima, Celzard, Alain, Belaissaoui, Bouchra, Roizard, Denis, Schneider, Raphaël, Muhr, Laurence, Canabady-Rochelle, Laetitia, Laboratoire Réactions et Génie des Procédés (LRGP), and Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL)

Subjects
[SPI]Engineering Sciences [physics], [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

9. Screening and Purification of Metal Chelating Peptides in Hydrolysates for their Antioxidant Properties

Author

Canabady-Rochelle, Laetitia, Paris, Cédric, Selmeczi, Katalin, Gaucher-Di Stasio, Caroline, Clarot, Igor, Leroy, Pierre, Alem, Halima, Schneider, Raphaël, Chaimbault, Patrick, Muhr, Laurence, Boschi-Muller, Sandrine, CANABADY-ROCHELLE, Laetitia, Laboratoire Réactions et Génie des Procédés (LRGP), Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL), Laboratoire d'Ingénierie des Biomolécules (LIBio), Université de Lorraine (UL), Structure et Réactivité des Systèmes Moléculaires Complexes (SRSMC), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), Cibles thérapeutiques, formulation et expertise pré-clinique du médicament (CITHEFOR), Institut Jean Lamour (IJL), Université de Lorraine (UL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), IMPACT Biomolécules, ANR-15-IDEX-0004,LUE,Isite LUE(2015), and ISITE - Isite LUE - - LUE2015 - ANR-15-IDEX-0004 - IDEX - VALID

Subjects
[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, [SPI]Engineering Sciences [physics], [CHIM.ANAL] Chemical Sciences/Analytical chemistry, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, [SPI] Engineering Sciences [physics], [SDV.IDA]Life Sciences [q-bio]/Food engineering, [CHIM] Chemical Sciences, [CHIM]Chemical Sciences, [SDV.IDA] Life Sciences [q-bio]/Food engineering, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, ComputingMilieux_MISCELLANEOUS
Abstract

International audience; Reactive Oxygen Species (ROS) induced oxidation Ageing and various pathologies in human related to oxidative stress, in particular inflammatory bowel diseases with iron anemia complication Degradation of consumption products (food, cosmetic matrix) Living organisms developped their own antioxidant defenses against these ROS Imbalance Oxidative stress Importance to discover natural antioxidants and evaluation of their bioactivity An interdisciplinary approach Some results SPR using a M 2+-chip:-a miniaturized approach of IMAC-type affinity chromatography-screening of the most interesting sources of metal-chelating peptides. Positive correlations evidenced between SPR screening and metal chelation tests using UV-Vis spectrometry on five sources of peptides. The affinity parameters are determined by SPR on some synthetic model peptides and then used to predict the separation of peptides on IMAC chromatographic column. Novel chromatography-MS method currently developed:-Screening of metal-chelating peptides sequences in a given complex mixture-Methodology successfully setup on a mixture of synthetic peptides-Further tests on real hydrolysates Identified peptides currently assessed for their antioxidant activity by chemical metal chelation and by in cellulo tests. Potential health application-Treatment of ferriprive anemia related to MICI, or inversely to hematochromatosis-Anchoring of these chelating peptides on nanoparticles for bioimaging or therapeutic applications. Metal-chelating peptides obtained after protein hydrolysis-Antioxidant properties related to the inhibition of Fenton reaction, responsible of ROS production-Used in pharmaceutics, foods and cosmetic Novel strategy for the screening and purification of the peptides to target their antioxidant properties. Novel approach developed in order to save time. Currently developed methods for the screening and separation of metal-chelating peptides by Surface Plasmon Resonance (SPR) by mass spectrometry (MS) : identification of the peptide(s) of interest present in the complex mixture Determination of metal chelation capacity using UV-visible spectrophotometry

Published
2016

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