1. Factors influencing quality of life in cancer patients with bone metastases.
- Author
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Drogoman, Marian
- Subjects
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LITERATURE reviews , *BONE metastasis , *COMPACT bone , *CANCER patients , *RENAL cancer - Abstract
Introduction: Bone metastases are a fairly common complication of cancers such as breast, prostate, or lung cancer, these sites are also the most common sources of bone metastases, to which it also joins others such as thyroid and kidney cancer. With advances in the management of both solid tumors and their bone metastases, an improvement in patients' quality of life has also been achieved, however, patients with bone metastases have a deterioration in quality of life under the impact of certain factors that occur during the course of the disease. Purpose: This literature review aims to highlight the main factors involved in affecting the quality of life of oncological patients with bone metastases by processing data from the most relevant publications, as well as establishing unexplored areas and issues in previous research. Materials and methods: PubMed, Google Search Engine (Google Academic), Frontiers, SpringerLink, ResearchGate, BMC Cancer, Elsevier were used to identify relevant publications. The criteria for the inclusion and exclusion of publications have been established. After identifying all studies by searching the databases, they were included in the PRISMA diagram. Of the 127 studies identified, 21 were included in the literature review. Discussion: Of the quality-of-life assessment tools in patients with bone metastases, the QLQ-C30 questionnaire was found to be most commonly used in the studies, to which is added the additional questionnaire QLQ-BM22, prepared to complete the evaluation. Among the determinants identified in the studies as having an impact on quality of life were: gender, performance status and primary tumor histology. Other factors with significant impact were: age, level of education and employment status. Psychological symptoms such as helplessness, depression and anxiety were also common. These problems have interfered with the relationships and social activities of patients. Conclusions: The studies included in the literature review provide an overview of the many important factors involved in affecting the quality of life of oncological patients with bone metastases, including, as well as the presentation of less studied aspects that might have interference with the quality of life of these patients. Also, this literature review provides landmarks to new unexplored directions in order to identify new factors that impact the quality of life of patients with bone metastases. [ABSTRACT FROM AUTHOR]
- Published
- 2024