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Your search keyword '"Yamazaki, Eriko"' showing total 39 results
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39 results on '"Yamazaki, Eriko"'

36. Perfluorinated carboxylic and sulphonic acids in surface water media from the regions of Tibetan Plateau: Indirect evidence on photochemical degradation?

Author

Yamazaki, Eriko, Falandysz, Jerzy, Taniyasu, Sachi, Hui, Ge, Jurkiewicz, Gabriela, Yamashita, Nobuyoshi, Yang, Yong-Liang, and Lam, Paul K. S.

Subjects
*FLUORINATION, *CARBOXYLIC acids, *SULFONIC acids, *PHOTOCHEMISTRY, *CHEMICAL decomposition
Abstract

Perfluorinated surfactants and repellents are synthetic substances that have found numerous industrial and customer applications. Due to their persistence, at least two groups of these substances—perfluorinated carboxylic acids (PFCAs) and perfluorinated sulfonic acids (PFSAs)—are diffused widely in the environment. It is hypothesized that the Tibetan Plateau, is one of few unique places on the Earth, due to its topography, specifically the vast space and high elevation above sea level, geographic location, climate, high solar radiation, lack of industry, little urbanization and general lack of significant direct sources of pollution. There it is believed possible to gain an insight into atmospheric fate (possible photochemical degradation of higher molecular mass and formation of lower molecular mass PFCAs and PFSAs) of PFASs under un-disturbed environmental conditions. Ultratrace analytical method for PFCAs and PFSAs and use of transportation and field blanks, laboratory blanks and isotopically labelled surrogates for recovery control has allowed the determination of nine perfluorinated carboxylic acids and six perfluorinated sulfonic acids at ultra-trace levels in water based samples from the alpine dimension regions of the Tibetan Plateau, the eastern slope of Minya Konka peak at the eastern edge of the Tibetan Plateau, and also from the city of Chengdu from the lowland of the Sichuan Province in China. The specific compositional pattern of PFCAs and PFSAs and low levels of pollution with those compounds were observed in the central region of the Tibetan Plateau and in the region adjacent to the peaks of Minya Konka in the Eastern Tibetan Plateau. The fingerprint of the compositional pattern of PFCAs and PFSAs in water samples in the central region of the Tibetan Plateau and in the alpine region adjacent to the peaks of Minya Konka in the Eastern Tibetan Plateau may be explained by the result of photochemical degradation with dealkylation of longer chain compounds and formation of shorter chain compounds, which are more resistant to photochemical degradation. [ABSTRACT FROM PUBLISHER]

Published
2016
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37. General Principles for the Education and Training of GCP Inspectors: The Outcome of Discussions by International Regulatory Experts in the Discussion Group on the ICH E6 Guideline.

Author

Uyama, Yoshiaki, Yamazaki, Eriko, Clark, Katherine, Wang, Chao-Yi, Woro, Endang, Tong, Foo Yang, Sachidanandan, Sumitra, Rodriguez, Ana, Oh, Hojin, Saleh, Kamaruzaman, Cirunay, Joyce, Wapeewuttikorn, Akanid, Rogov, Evgeny, Alshahwan, Khaled W., Herrera, Ileana, Mthetwa, Joseph, Fakudze, Fortunate, and Osawa, Tomoko

Subjects
EVALUATION of clinical trials, MEDICAL protocols, GOVERNMENT regulation
Abstract

The article provides a summary of the background and past activities of the E6 Discussion Group established under the International Pharmaceutical Regulators Forum. Topics discusses include the establishment of the Regulators Forum to create a regulator-only environment, the development of a statement on general principles for the training and education of Good Clinical Practice (GCP) inspectors which will serve as a reference to regulatory agencies.

Published
2015
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38. Distribution and primary source analysis of per- and poly-fluoroalkyl substances with different chain lengths in surface and groundwater in two cities, North China.

Author

Yiming Yao, Hongkai Zhu, Bing Li, Hongwei Hu, Tao Zhang, Yamazaki, Eriko, Taniyasu, Sachi, Yamashita, Nobuyoshi, and Hongwen Sun

Subjects
FLUOROALKYL compounds, GROUNDWATER, CITIES & towns, STREAM chemistry, HIGH performance liquid chromatography, TANDEM mass spectrometry, RUNOFF, PERFLUOROOCTANOIC acid
Abstract

Per- and poly-fluoroalkyl substances (PFASs) have been widely detected in the hydrosphere. The knowledge on the distribution and composition patterns of PFAS analogues with different chain length significantly contribute to their source analysis. In the present study, a regional scale investigation of PFASs in surface river waters and adjacent ground waters was carried out in two cities of China with potential contamination, Tianjin and Weifang. A total of 31 water samples were collected, and 20 PFASs therein were measured by a high-performance liquid chromatograph–tandem mass spectrometer (HPLC–MS/MS). The possible sources of PFASs in the aquatic environment were assessed primarily by concentration patterns as well as hierarchical cluster analysis. In all 4 rivers investigated in the two cities, perfluoroalkyl carboxylic acids (PFCAs) were the dominant compounds contributing over 70% of the PFASs detected. Perfluorooctanoic acid (PFOA) was the dominant PFCA with a concentration range of 8.58–20.3 ng/L in Tianjin and 6.37–25.9 ng/L in Weifang, respectively. On the average, the highest concentration was observed in samples from Dagu Drainage Canal (Dagu) in Tianjin and those short-chain PFASs (C4–C6) was detected with a comparable level of the longer-chain PFASs (>C6). Specifically, perfluorobutanoic acid (PFBA) was dominant in the short-chain analogues. This indicates that a remarkably increasing input of short-chain PFASs might be related to wastewater treatment plant effluent or industrial discharges, which could be possibly due to the switch of manufacturing to short-chain products. In Weifang, precipitation and subsequent surface runoff as non-point sources could be significant inputs of PFASs into surface water while groundwater was possibly subjected to severe point sources with ∑PFASs concentration up to ~100 ng/L. The inconsistent distribution patterns in groundwater suggest complicated pathways of contamination. [ABSTRACT FROM AUTHOR]

Published
2014
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39. Combined surgery for ischemic cardiomyopathy: Report of a case.

Author

Ishikawa, Susumu, Ueda, Keisuke, Kawasaki, Akio, Neya, Kazuo, Abe, Keiko, Suzuki, Haruo, Shirato, Hiroyuki, Yamazaki, Eriko, and Aoyagi, Yoshiko

Subjects
SURGERY, CARDIOMYOPATHIES, CORONARY artery bypass, CORONARY disease
Abstract

Summary: A 65-year-old female with catecholamine-dependent ischemic cardiomyopathy was admitted to our hospital. Preoperative examination revealed severe triple vessel coronary artery disease, severe mitral valve regurgitation and left ventricular (LV) dilatation associated with low ejection fraction. Coronary artery bypass grafting with four distal anastomoses, mitral valve plasty using original papillary muscle application method, LV volume reduction using overlapping method and biventricular pacing were performed. Postoperative course was uneventful and quality of life at 2 years after surgery was good. Active combined surgery has the possibility of improving the outcome of patients with severe ischemic cardiomyopathy. [Copyright &y& Elsevier]

Published
2008
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