161 results on '"Weber, Tilmann"'
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2. Comparative genomics unravels a rich set of biosynthetic gene clusters with distinct evolutionary trajectories across fungal species (Termitomyces) farmed by termites
3. Commensal production of a broad-spectrum and short-lived antimicrobial peptide polyene eliminates nasal Staphylococcus aureus
4. Streptomyces alleviate abiotic stress in plant by producing pteridic acids
5. UmetaFlow: an untargeted metabolomics workflow for high-throughput data processing and analysis
6. Identification and heterologous expression of the globomycin biosynthetic gene cluster
7. High-quality genome-scale metabolic network reconstruction of probiotic bacterium Escherichia coli Nissle 1917
8. Genome-Led Discovery of the Antibacterial Cyclic Lipopeptide Kutzneridine A and Its Silent Biosynthetic Gene Cluster from Kutzneria Species.
9. Antitumor astins originate from the fungal endophyte Cyanodermella asteris living within the medicinal plant Aster tataricus
10. A treasure trove of 1034 actinomycete genomes.
11. Maramycin, a Cytotoxic Isoquinolinequinone Terpenoid Produced through Heterologous Expression of a Bifunctional Indole Prenyltransferase/Tryptophan Indole-Lyase in S. albidoflavus.
12. BGCFlow: systematic pangenome workflow for the analysis of biosynthetic gene clusters across large genomic datasets.
13. Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST
14. A versatile genetic engineering toolkit for E. coli based on CRISPR-prime editing
15. Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters
16. CRISPR–Cas9, CRISPRi and CRISPR-BEST-mediated genetic manipulation in streptomycetes
17. Synthetic biology and metabolic engineering of actinomycetes for natural product discovery
18. Genome-Driven Discovery of Hygrocins in Streptomyces rapamycinicus.
19. Pepticinnamins N, O, and P, Nonribosomal Peptides from the Soil-Derived Streptomyces mirabilis P8-A2.
20. Biosynthesis of the Azoxy Compound Azodyrecin from Streptomyces mirabilis P8-A2.
21. teemi: An open-source literate programming approach for iterative design-build-test-learn cycles in bioengineering.
22. Sequence-based classification of type II polyketide synthase biosynthetic gene clusters for antiSMASH
23. Linking secondary metabolites to biosynthesis genes in the fungal endophyte Cyanodermella asteris: The anti-cancer bisanthraquinone skyrin
24. Dilarmycins A–C, Calcium-Dependent Lipopeptide Antibiotics with a Non-canonical Ca2+-Binding Motif.
25. The antiSMASH database version 4: additional genomes and BGCs, new sequence-based searches and more.
26. Reprogramming Acyl Carrier Protein Interactions of an Acyl-CoA Promiscuous trans-Acyltransferase
27. In silico tools for the analysis of antibiotic biosynthetic pathways
28. Systems Analysis of Highly Multiplexed CRISPR-Base Editing in Streptomycetes.
29. antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation.
30. Identification and activation of novel biosynthetic gene clusters by genome mining in the kirromycin producer Streptomyces collinus Tü 365
31. Crossiellidines A–F, Unprecedented Pyrazine-Alkylguanidine Metabolites with Broad-Spectrum Antibacterial Activity from Crossiella sp.
32. Properties of Multidrug-Resistant Mutants Derived from Heterologous Expression Chassis Strain Streptomyces albidoflavus J1074.
33. Synthetic Biology of secondary metabolite biosynthesis in actinomycetes: Engineering precursor supply as a way to optimize antibiotic production
34. Dissemination of antibiotic resistance genes from antibiotic producers to pathogens
35. Long-Read Metagenome-Assembled Genomes Improve Identification of Novel Complete Biosynthetic Gene Clusters in a Complex Microbial Activated Sludge Ecosystem.
36. Increased glycopeptide production after overexpression of shikimate pathway genes being part of the balhimycin biosynthetic gene cluster
37. Identification of the Biosynthetic Gene Cluster for Pyracrimycin A, an Antibiotic Produced by Streptomyces sp.
38. Pangenome analysis of Enterobacteria reveals richness of secondary metabolite gene clusters and their associated gene sets.
39. Comparative analysis and insights into the evolution of gene clusters for glycopeptide antibiotic biosynthesis
40. antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers
41. Evidence that an additional mutation is required to tolerate insertional inactivation of the Streptomyces lividans recA gene
42. NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity
43. antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences
44. Transcriptional and mutational analyses of the Streptomyces lividans recX gene and its interference with RecA activity
45. Complete genome sequence of the kirromycin producer Streptomyces collinus Tü 365 consisting of a linear chromosome and two linear plasmids
46. Specificity prediction of adenylation domains in nonribosomal peptide synthetases (NRPS) using transductive support vector machines (TSVMs)
47. Die Struktur des Cyclodecatriens Collinolacton, seine Biosynthese und semisynthetische Derivate: monopolare Spindeln und Schutz vor intrazellulärem oxidativem Stress.
48. The Structure of Cyclodecatriene Collinolactone, its Biosynthesis, and Semisynthetic Analogues: Effects of Monoastral Phenotype and Protection from Intracellular Oxidative Stress.
49. Towards the sustainable discovery and development of new antibiotics.
50. antiSMASH 6.0: improving cluster detection and comparison capabilities.
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