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1. IVIg-induced headache: prospective study of a large cohort with neurological disorders

Author

Hasırcı Bayır, Buse Rahime, Ünsal, Miraç Ayşen, Ağırcan, Cansu, Cerrahoğlu Şirin, Tuba, Akan, Onur, Gürsoy, Gizem, Eyigürbüz, Tuğba, Mermi Dibek, Dilara, Akdağ, Gönül, Elmalı, Ayşe Deniz, Nazlı, Ezgi, Akkoyun Arıkan, Fatma, Alpaydın Baslo, Sezin, Ağırcan, Dilek, Oguz-Akarsu, Emel, Ertürk Çetin, Özdem, Gesoğlu Demir, Tülin, Acıman Demirel, Esra, Vurallı, Doğa, Deveci, Şule, Tanyel, Tuba, Mayda Domaç, Füsun, Karlı, Necdet, Velioğlu, Sibel, and Baykan, Betül

Published
2023
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2. Exploring shared triggers and potential etiopathogenesis between migraine and idiopathic/genetic epilepsy: Insights from a multicenter tertiary-based study

Author

Yapıcı, Zuhal, Midi, İpek, Saygı, Serap, Çelebi, Ulufer, Darol, Elif Sarıca, Ağan, Kadriye, Ayça, Senem, Gazioğlu, Sibel, Okudan, Zeynep Vildan, Şirin, Nermin Görkem, Bebek, Nerses, Dericioğlu, Neşe, Altun, İlknur Güçlü, Yalçın, Ayşe Destina, Sürmeli, Reyhan, Erdinç, Oğuz Osman, Erdal, Abidin, Algın, Demet İlhan, Kutlu, Gülnihal, Bek, Semai, Erdal, Yüksel, Özön, Akçay Övünç, Reyhani, Aylin, Güldiken, Babürhan, Baklan, Barış, Genç, Bülent Oğuz, Altındağ, Ebru Aykutlu, Karahan, Gökçen, Koç, Güray, Mısırlı, Handan, Öztura, İbrahim, Aslan-Kara, Kezban, Çakar, Merve Melodi, Türkmen, Nur, Bulut, Onur, Karadaş, Ömer, Şahin, Özlem Kesim, Ferik, Sevgi, Peköz, Mehmet Taylan, Topaloğlu, Pınar, Özek, Sibel Üstün, Düzgün, Ülkühan, Yayla, Vildan, Gömceli, Yasemin, Acar, Zeynep Ünlüsoy, Türk, Bengi Gül, Yeni, Seher Naz, Atalar, Arife Çimen, Ekizoğlu, Esme, Gök, Duygu Kurt, Baykan, Betül, Özge, Aynur, Ayta, Semih, Erdoğan, Füsun Ferda, Taşdelen, Bahar, and Velioğlu, Sibel K.

Published
2024
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3. The effect of sleep disorders on quality of life in patients with epilepsy: A multicenter study from Turkey

Author

Akdağ, Gönül, Canbaz Kabay, Sibel, Bican Demir, Aylin, Ergin Bakar, Ebru, Koç, Güray, Üstün Özek, Sibel, Küçük, Ahmet, Ünsal, Miraç Ayşen, Neyal, Abdurrahman, Florentina Ateş, Miruna, Çelik, Havva Tuğba, Kılıçparlar Cengiz, Emine, Kutlu, Gülnihal, Ağırcan, Dilek, Karacan Gölen, Meltem, Bek, Semai, Çınar, Nilgün, Sahin, Sevki, Şişman Bayar, Aysel Büşra, Terzi, Murat, Kendirli Aslan, Sude, Kenar, Safiye Gül, Kutluhan, Süleyman, Ekmekyapar Fırat, Yasemin, Yılmaz Okuyan, Dilek, Bayar, Muhammet Duran, Mert Atmaca, Murat, Yalçın, Destina, Genç, Fatma, Köse Leba, Leyla, Yılmaz, Buket, Eren, Fettah, Bolu, Naci Emre, Keskin Güler, Selda, Akıncı, Tuba, Reyhani, Aylin, Yıldırım Sitembölükbaşı, Neslişah, Türkmen, Nur, Karşıdağ, Sibel, Velioğlu, Sibel K., Demir, Ayşegül, Haytı, Barış, Hasırcı Bayır, Buse Rahime, Ezgi Uçan Tokuç, Firdevs, Demir, Göksemin, Çakmakçı, Güngör, Özkan, Hülya, Bulut, Onur, Kesim Şahin, Özlem, Sürmeli, Reyhan, Tekin, Selma, Sarıoğlu, Şerife Gizem, Gesoğlu Demir, Tülin, Akkoyun Arıkan, Fatma, and Çetiner, Mustafa

Published
2024
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4. Global uncertainty in the diagnosis of neurological complications of SARS-CoV-2 infection by both neurologists and non-neurologists: An international inter-observer variability study

Author

Abbariao, Maritoni, Zaki, Shafiq Dexter Abou, Aleksic, Dejan, Aliling, Nicole, Rivas, Susana Arias, Artajos, Godard, Asukile, Melody, Atalar, Arife Çimen, Bae, Jong Seok, Banzrai, Chimeglkham, Bar, Michal, Barone, Valentina, Baykan, Betul, Beghi, Ettore, Berger, Thomas, Bilic, Ivica, Biller, Jose, Boskovic, Mateja, Cabreira, Verónica, Calado, Sofia, Canete, Maria Teresa, Celebisoy, Nese, Chen, Ike Leon, Chishimba, Lorraine, Chomba, Mashina, Constantino, Glenn Anthony, Cotelli, Maria Sofia, De Cauwer, Harald, Debroucker, Thomas, Orantes, Luis Del Carpio, Devaraj, Rashmi, D'Souza, Michelle, Ekizoglu, Esme, Elmali, Ayse Deniz, Fonseca, Ana Catarina, Furloni, Roberto, Gajre, Sunil, Azorin, David Garcia, Garfoot, Vanessa, Gasparic, Irena, Genç, Hamit, Glavica, Marinka, Guanaes, Luiz Gustavo, Gürsoy, Gizem, Hafiz, Nauman, Hasırcı, Buse, Helbok, Raimund, Hor, Chee Peng, Hughes, Stella, Hwang, Sungeun, Kaya, Irem Ilgezdi, Jakupi, Adi, Jamora, Roland Dominic, Kahwagi, Jamil, Kaprelyan, Ara, Kawatu, Nfwama, Kim, Manho, Kim, Hyunji, Kim, Hyun Kyung, Koffie, Desmond, Ladeira, Filipa, Lant, Suzannah, Lee, Woo-Jin, Lee, Sukyoon, Leonardo, Zerlyn, Lim, Christian Emmanuel, Lisak, Marijana, Loh, Hong Chuan, Loo, Lay Khoon, Huzjan, Arijana Lovrencic, Koh, Rosie Sue Luan Lu, Luabeya, Mesu'a Kabwa, Lugaresi, Alessandra, Macrohon, Bernadette, Majdak, Maja, Manalili, Sheryl, Manelli, Filippo, Mapoure, Yacouba Njankouo, Mascarella, Davide, Massano, João, Mataa, Mataa, Matibag, Jessica Leika, Matic-Gerodias, Alexandria, McMullen, Kate, Miranda, Miguel, Modequillo, Margaret, Shoab, Abul Kalam Mohammed, Motto, Cristina, Murphy, Sinead M., Mwendaweli, Naluca, Ng, Chen Fei, Ng, Rong Xiang, Ihsan, Mohd Khairul Nizam Nor, Nyein, Aye Myat, O'Connell, Karen, Oh, Seong-il, Ohnmar, Ohnmar, Özge, Aynur, Pajo, Azalea, Palavra, Filipe, Panteleienko, Larysa, Payne, Catherine, Pensato, Umberto, Peres, João, Peters, Steven, Polat, Burcu, Poljakovic, Zdravka, Punter, Martin Nicholas Michael, Quiles, Liz Edenberg, Ranieri, Angelo, Ratković, Marija, Renales, Maria Lina, Robles, Jose, Bedeković, Marina Roje, Rommer, Paulus, Šapina, Lidija, Sarac, Helena, Saylor, Deanna, Schmutzhard, Erich, Sharma, Anahita, Šimić, Aleksandra, Sipilä, Jussi O.T., Sokhi, Dilraj, Stagno, Mauro, Stancheva, Kristina, Stojsavljević, Marija, Subir, Ahamed, Surdhar, Sushee, Talabucon, Loreto, Jr, Tan, Hui Jan, Teoh, Sing Chiek, Vallejo, Dionis, Velioglu, Sibel K., Vukasović, Rafaela, Kit, Wong Wai, Welte, Tamara, Willekens, Barbara, Yesilot, Nilufer, Yu, Jeryl Ritzi T., Zaw, Moe Moe, Zhelyazkova, Sashka, Žitnik, Eva, Tamborska, A.A., Wood, G.K., Westenberg, E., Garcia-Azorin, D., Webb, G., Schiess, N., Netravathi, M., Baykan, B., Dervaj, R., Helbok, R., Lant, S., Özge, A., Padovani, A., Saylor, D., Schmutzhard, E., Easton, A., Lilleker, J.B., Jackson, T., Beghi, E., Ellul, M.A., Frontera, J.A., Pollak, T., Nicholson, T.R., Wood, N., Thakur, K.T., Solomon, T., Stark, R.J., Winkler, A.S., and Michael, B.D.

Published
2023
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5. Peri-ictal headache: An underestimated prognostic finding associated with idiopathic epilepsies

Author

Yapıcı, Zuhal, Midi, İpek, Saygı, Serap, Çelebi, Ulufer, Sarıca Darol, Elif, Ağan, Kadriye, Ayça, Senem, Gazioğlu, Sibel, Vildan Okudan, Zeynep, Görkem Şirin, Nermin, Bebek, Nerses, Dericioğlu, Neşe, Güçlü Altun, İlknur, Destina Yalçın, Ayşe, Sürmeli, Reyhan, Osman Erdinç, Oğuz, Erdal, Abidin, İlhan Algın, Demet, Kutlu, Gülnihal, Bek, Semai, Erdal, Yüksel, Övünç Özön, Akçay, Reyhani, Aylin, Güldiken, Babürhan, Baklan, Barış, Oğuz Genç, Bülent, Aykutlu Altındağ, Ebru, Karahan, Gökçen, Koç, Güray, Mısırlı, Handan, Öztura, İbrahim, Aslan-Kara, Kezban, Melodi Çakar, Merve, Türkmen, Nur, Bulut, Onur, Karadaş, Ömer, Kesim Şahin, Özlem, Ferik, Sevgi, Taylan Peköz, Mehmet, Üstün Özek, Sibel, Düzgün, Ülkühan, Yayla, Vildan, Gömceli, Yasemin, Ünlüsoy Acar, Zeynep, Ekizoglu, Esme, Baykan, Betül, Çimen Atalar, Arife, Gül Türk, Bengi, Kurt Gök, Duygu, Topaloglu, Pınar, Özge, Aynur, Ayta, Semih, Ferda Erdoğan, Füsun, Naz Yeni, Seher, Taşdelen, Bahar, and Velioğlu, Sibel K.

Published
2023
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9. Diagnosis of comorbid migraine without aura in patients with idiopathic/genetic epilepsy based on the gray zone approach to the International Classification of Headache Disorders 3 criteria

Author

Atalar, Arife Çimen, Özge, Aynur, Türk, Bengi Gül, Ekizoğlu, Esme, Kurt Gök, Duygu, Baykan, Betül, Ayta, Semih, Erdoğan, Füsun Ferda, Yeni, Seher Naz, Taşdelen, Bahar, and Velioğlu, Sibel K.

Subjects
Neurology, Neurology (clinical)
Abstract

BackgroundMigraine without aura (MwoA) is a very frequent and remarkable comorbidity in patients with idiopathic/genetic epilepsy (I/GE). Frequently in clinical practice, diagnosis of MwoA may be challenging despite the guidance of current diagnostic criteria of the International Classification of Headache Disorders 3 (ICHD-3). In this study, we aimed to disclose the diagnostic gaps in the diagnosis of comorbid MwoA, using a zone concept, in patients with I/GEs with headaches who were diagnosed by an experienced headache expert.MethodsIn this multicenter study including 809 consecutive patients with a diagnosis of I/GE with or without headache, 163 patients who were diagnosed by an experienced headache expert as having a comorbid MwoA were reevaluated. Eligible patients were divided into three subgroups, namely, full diagnosis, zone I, and zone II according to their status of fulfilling the ICHD-3 criteria. A Classification and Regression Tree (CART) analysis was performed to bring out the meaningful predictors when evaluating patients with I/GEs for MwoA comorbidity, using the variables that were significant in the univariate analysis.ResultsLonger headache duration (n = 62) in the CART analysis were 48.39% Juvenile myoclonic epilepsy followed by 25.81% epilepsy with generalized tonic-clonic seizures alone.ConclusionLonger headache duration, throbbing pain, increase of pain by physical activity, photophobia and/or phonophobia, presence of vertigo/dizziness, osmophobia, and higher VAS scores are the main supportive associated factors when applying the ICHD-3 criteria for the comorbid MwoA diagnosis in patients with I/GEs. Evaluating these characteristics could be helpful to close the diagnostic gaps in everyday clinical practice and fasten the diagnostic process of comorbid MwoA in patients with I/GEs.

Published
2023
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10. One Patient, Three Providers: A Multidisciplinary Approach to Managing Common Neuropsychiatric Cases.

Author

Özge, Aynur, Domaç, Füsun Mayda, Tekin, Nil, Sünbül, Esra Aydın, Öksüz, Nevra, Atalar, Arife Çimen, Çallı, Sümeyye Yasemin, Fidan, Yağmur Sever, Evlice, Ahmet, Beştepe, Engin Emrem, İzci, Filiz, Küsbeci, Özge Yılmaz, Demirel, Esra Acıman, Velioğlu, Sibel K., and Ungan, Mehmet

Subjects
MEDICAL personnel, AFFECTIVE disorders, PHYSICIANS' attitudes, BIPOLAR disorder, MEDICATION abuse, POSTHERPETIC neuralgia, EPILEPSY
Abstract

Background: Neuropsychiatric cases require a multidisciplinary approach for effective management. This paper presented case-based discussions on migraine, dementia, epilepsy, mood disorders, neuralgia, and psychosis from the perspectives of a family physician, neurologist, and psychiatrist. The goal was to highlight the importance of collaboration between healthcare providers in managing these complex cases. Methods: The paper was based on the proceedings of the Mediterranean Neuropsychiatry Symposium, where experts from family medicine, neurology, and psychiatry came together for comprehensive case-based discussions. The CARE framework (Case Report, Appraisal, Research, and Education) was developed to guide reporting and evaluation of case reports in clinical practice. Results: Six cases were presented and discussed, highlighting the importance of a multidisciplinary approach in managing neuropsychiatric cases. The cases included chronic migraine with medication overuse, memory dysfunction with language and behavioral problems, refractory epileptic seizures with subjective sensory symptoms, bipolar affective disorder with normal pressure hydrocephalus, postherpetic neuralgia in a case with bipolar affective disorder, and psychosis with recurrent attacks with the abuse of several substances. Conclusion: A biopsychosocial multidisciplinary approach is essential for managing neuropsychiatric cases effectively on behalf of the patients and public health of the country. The CARE framework can guide the reporting and evaluation of case reports in clinical practice, ensuring that patients receive comprehensive and effective care. Healthcare providers should collaborate to provide the best possible care for patients with complex and multifaceted needs. [ABSTRACT FROM AUTHOR]

Published
2023
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15. COVID-19 ve Epilepsi: Nöbetlere, Tedaviye ve Sosyal Yaşama Etkileri.

Author

ELMALI, Ayşe Deniz, BEBEK, Nerses, YILDIRIM, İrem, AYTA, Semih, ALTINDAĞ, Ebru, ASLAN, Kezban, VELİOĞLU, Sibel K., and YENİ, Seher Naz

Subjects
CONVULSIONS -- Risk factors, RISK factors of spasms, ANTICONVULSANTS, EPILEPSY, RISK assessment, TELEMEDICINE, COVID-19
Abstract

Copyright of Epilepsi: Journal of the Turkish Epilepsi Society is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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16. Congenital Bilateral Perisylvian Syndrome: A Case Report.

Author

GAZİOĞLU, Sibel, ALTUNAYOĞLU ÇAKMAK, Vildan, EYÜBOĞLU, İlker, AKPINAR, Ramazan, and VELİOĞLU, Sibel

Subjects
HUMAN abnormalities, EPILEPSY, PSEUDOBULBAR paralysis, COGNITION disorders, MAGNETIC resonance imaging of the brain, DIAZEPAM, CARBAMAZEPINE
Abstract

Copyright of Epilepsi: Journal of the Turkish Epilepsi Society is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2014
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17. İlaca Dirençli Epilepsisi Olan Çocuklarda Farmakolojik Olmayan Alternatif Tedavi Yaklaşımları: Vagus Sinir Stimülasyonu ve Ketojenik Diyet.

Author

VELİOĞLU, Sibel K.

Abstract

Approximately 20%-30% of individuals who develop epilepsy will develop medically refractory epilepsy. For this population, ''alternative'' or nonpharmacologic treatments such as vagus nerve stimulation (VNS) and ketogenic diet (KD) can be highly efficacious and should be seriously considered. Children and young people with medically-resistant epilepsy and poor candidates for epilepsy surgery may be referred to a tertiary paediatric epilepsy specialist for consideration of introducing VNS or KD. Information on the availability of VNS and KD in children is limited yet, due to the lack of suitably designed clinical studies in this population. VNS, is well-tolerated and effective as add-on therapy for refractory seizures in children. There has been no indication of reduction of effectiveness in long-term, open studies. Complications associated with implantation includes infection at the incision site, rib fractures and transient paralysis of the left vocal cord. Special caution is advised for children with pre-existing sleep apnea, cardiac conduction disorders, and asthma. Decreased seizure severity and recovery time, abolition of daytime drop attacks, and reduced hospitalization due to SE have improved patients' quality of life. KD, with a nonfat-to-fat ratio of 1:4 is a nonpharmacologic treatment for children with intractable epilepsy. Recent reports suggest that the benefit of KD is equivalent to any of the new anticonvulsant medications. The KD is difficult to maintain and has common side effects as constipation, acidosis, hypercholesterolemia, kidney stones, and hunger. It seems possible to design a therapy that is less rigorous and intrusive than the current KD, and promising alternative dietary approaches such as the Atkins and Low-glycemic-index (LGI) diet are emerging. [ABSTRACT FROM AUTHOR]

Published
2014
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18. Comparison of Psychiatric Features Between Conversion Disorder and Female Epilepsy Patients with Non-Intractable Seizure.

Author

ÖZKORUMAK, Evrim, GAZİOĞLU, Sibel, TİRYAKİ, Ahmet, VELİOĞLU, Sibel K., and KIZILAY, Pınar

Subjects
PEOPLE with epilepsy, WOMEN patients, CONVERSION disorder, OUTPATIENT medical care, CARE of people, PEOPLE with mental illness, PSYCHIATRIC clinics
Abstract

Copyright of Epilepsi: Journal of the Turkish Epilepsi Society is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2014
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19. Spectrum of hyperexcitability of the brain: migraine and pain sensitivity in epilepsy.

Author

Velioğlu, Sibel K.

Subjects
*EPILEPSY, *EPILEPSY in animals, *PAIN threshold, *MIGRAINE, *MIGRAINE aura, *LABORATORY animals, *COMORBIDITY, *ANIMAL models in research
Abstract

The process that provoke spontaneous seizures that characterizes epilepsy is related to a decrease in the threshold of excitability of neurons. The pathophysiological mechanisms that drive neurons to generate abnormal excessive electrical discharges are still not clearly understood. These neurons, which are silent/calm in the interictal period, are different from normal neurons in many aspects. The conditions that are commonly comorbid with epilepsies, are headaches and painful syndromes. Scientific research on this comorbidity is only limited to clinical studies and has not yet reached results that will clarify the neurobiology of the association. Implementing animal models that have both the disease and the comorbidity and preclinical studies to be performed on them are difficult as methodology, and there is no such study yet. In recent years, two preclinical studies we conducted in experimental animals with genetic epilepsy showed that the pain threshold is reduced in genetic absence epilepsy. Future studies on pain comorbidity in epilepsy will shed a light on the neurobiology of both epilepsy and pain. In this presentation, the neurobiology of epilepsy will be discussed in terms of comorbidity of epilepsy-migraine, and the pain threshold studies in rats with genetic absence epilepsy. [ABSTRACT FROM AUTHOR]

Published
2020

20. Four novel and two recurrent NHLRC1 (EPM2B) and EPM2A gene mutations leading to Lafora disease in six Turkish families

Author

Salar, Seda, Yeni, Naz, Gündüz, Ayşegül, Güler, Ayşe, Gökçay, Ahmet, Velioğlu, Sibel, Gündoğdu, Aslı, and Hande Çağlayan, S.

Subjects
*MYOCLONUS, *DISEASE relapse, *GENETIC mutation, *ETIOLOGY of diseases, *PEOPLE with epilepsy, *DIAGNOSIS
Abstract

Summary: Lafora disease (LD) is a type of autosomal recessive, progressive myoclonus epilepsy resulting mostly from mutations in the EPM2A and NHLRC1 genes. Mutational analysis in both genes was initiated with the aim of establishing LD DNA diagnosis in Turkey. Four novel NHLRC1 (p.G131X, p.P69S and p.D82H) and EPM2A (p.V7A) and two recurrent NHLRC1 (p.D146N) and EPM2A (p.R241X) mutations were identified in six families. The delineation of causative mutations in patients provided early disease diagnosis for other family members and contributed to the knowledge of LD pathogenesis. [ABSTRACT FROM AUTHOR]

Published
2012
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