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4 results on '"Trentacoste, Jessica"'

1. Palliative care needs among outpatient adults with cystic fibrosis: Baseline data from the Improving Life with CF trial

Author

DiFiglia, Stephanie, Georgiopoulos, Anna M., Portenoy, Russell, Seng, Elizabeth, Berdella, Maria, Friedman, Deborah, Kier, Catherine, Linnemann, Rachel W., Middour-Oxler, Brandi, Walker, Patricia, Wang, Janice, Yonker, Lael M., Buehler, Brian, Chaudhary, Nivedita, Esposito, Christine, Frantzen, Theresa, Henthorne, Katherine, Plachta, Amy, Pollinger, Sophie, Stables-Carney, Teresa, Trentacoste, Jessica, and Dhingra, Lara

Published
2024
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2. The clinical impact of the Covid-19 pandemic first wave on patients with cystic fibrosis in New York

Author

Simonson, Joseph L., Esposito, Christine, Frantzen, Theresa, Henthorne, Katherine, Espinal, Aileen, Romano, Serena, Ramdeo, Ramona, Trentacoste, Jessica, Tsang, Donna, LaVecchia, Geralyn, Abdullah, Robert, Berdella, Maria, Bonitz, Lynn, Condos, Rany, Constantinescu, Andrei, DeCelie-Germana, Joan K., DiMango, Emily, Draine, Myah, Gimeli, Tara, Giusti, Robert, Guzman, Jessenia, Hammouda, Soumia, Keating, Claire, Kier, Catherine, Lennox, Alison T., Liriano, Carmen, Messer, Zachary, Plachta, Amy, Sadeghi, Hossein, Schwind, Elinor, Stables-Carney, Teresa, Walker, Patricia, and Wang, Janice

Published
2022
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3. Advances in the Cystic Fibrosis Drug Development Pipeline.

Author

Esposito, Christine, Kamper, Martin, Trentacoste, Jessica, Galvin, Susan, Pfister, Halie, and Wang, Janice

Subjects
CYSTIC fibrosis transmembrane conductance regulator, CYSTIC fibrosis, LIFE expectancy, CHLORIDE channels, DRUG development, THERAPEUTICS, MUCOCILIARY system
Abstract

Cystic fibrosis is a genetic disease that results in progressive multi-organ manifestations with predominance in the respiratory and gastrointestinal systems. The significant morbidity and mortality seen in the CF population has been the driving force urging the CF research community to further advance treatments to slow disease progression and, in turn, prolong life expectancy. Enormous strides in medical advancements have translated to improvement in quality of life, symptom burden, and survival; however, there is still no cure. This review discusses the most current mainstay treatments and anticipated therapeutics in the CF drug development pipeline within the mechanisms of mucociliary clearance, anti-inflammatory and anti-infective therapies, restoration of the cystic fibrosis transmembrane conductance regulator (CFTR) protein (also known as highly effective modulator therapy (HEMT)), and genetic therapies. Ribonucleic acid (RNA) therapy, gene transfer, and gene editing are being explored in the hopes of developing a treatment and potential cure for people with CF, particularly for those not responsive to HEMT. [ABSTRACT FROM AUTHOR]

Published
2023
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4. THE CLINICAL IMPACT OF COVID-19 ON CYSTIC FIBROSIS PATIENTS IN NEW YORK.

Author

Simonson, Joseph, ESPOSITO, Christine, Frantzen, Theresa, Henthorne, Katherine, Ramdeo, Ramona, Trentacoste, Jessica, Tsang, Donna, La Vecchia, Geralyn, Abdullah, Robert, Berdella, Maria, Bonitz, Lynn, Condos, Rany, Constantinescu, Andrei, DeCelie- Germana, Joan, Di Mango, Emily, Giusti, Robert, Keating, Claire, Kier, Catherine, Lennox, Alison, and Sadeghi, Hossein

Subjects
COVID-19, CYSTIC fibrosis
Published
2021
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