Search

Plasmablastic lymphoma (PBL) is a rare and aggressive non- Hodgkin 's B-cell lymphoma initially reported in patients with the HIV virus with a predilection for the oral cavity. It can affect individuals with other types of immunodeficiency and appear in extra-oral sites, also demonstrating an association with Epstein-Barr Virus (EBV) infection. Histopathological diagnosis is challenging due to overlapping features of other high-grade lymphomas and plasma cell lesions. The objective of the study was to report two cases of oral manifestations of Plasmablastic Lymphoma, in a patient with different HIV serological status and EBV positivity, aiming to present and discuss information regarding the clinical presentation, laboratory and immunohistochemical findings, proposed treatment and a review of updated literature on the topic.

Angiosarcomas are rare and aggressive malignant tumors of endothelial cells, they have a vascular or lymphatic origin. Diagnostic evaluation includes a biopsy to confirm the histopathological diagnosis, in addition to magnetic resonance imaging to delineate the extent of the primary lesion before surgery. We report an unusual clinical event of well-differentiated angiosarcoma in the nasogingival labial region in a female patient, 85-years-old, who sought care with increased sensitivity in the upper lip with progressive worsening and the appearance of pain and local edema. After a biopsy and immunohistochemical study, she was diagnosed with well-differentiated nasogingivolabial angiosarcoma. The patient underwent extensive surgical resection of the lesion with nasal amputation, resection of the upper lip, and partial palatectomy associated with postoperative radiotherapy. Then, she was referred to the oral and maxillofacial prosthesis service for rehabilitation. The patient was diagnosed with advanced stage metastasis in the liver 25 months after the surgical treatment, being under palliative care. Eight months later, the patient died. We also present a discussion of clinical and histopathological aspects, differential diagnosis and treatment modalities, In addition to a brief review of the literature on the subject.

Introduction: Periodontitis, a complex infectious disease that may lead to irreversible loss of periodontium, is considered a predisposing agent for developing insulin resistance due to the release of inflammatory mediators, showing a bilateral relationship with diabetes mellitus. The investigation of periodontal disease requires a clinical approach and complete intraoral radiographs, even with increasing concerns about radiation exposure. Thus, this study assesses pixel linear analysis accuracy using digital radiography via Digora® in detecting alveolar bone destruction in diabetic rats with periodontal disease. Methodology: 40 rats were divided into groups (n = 10): control (C), rats with periodontal disease (PD), experimental diabetic rats (ED), experimental diabetic rats with periodontal disease (ED-PD). Diabetes was induced by streptozotocin and periodontal disease by periodontal ligature. After 30 days, maxillae bone destruction was obtained by linear analysis of vertical bone loss using digital radiography and then assessed by micro-CT and histology. Data were analyzed by ANOVA and Tukey’s test (p

Background: Maxillary sinus mucocele is a benign cystic lesion caused due to mucus retention. The aim of this article is to relate a singular case of MSM development after dental extraction. We believe that previous dental extraction procedure of teeth 26, must have established some degree of Oroantral Comunnication, allowing the maxillary sinus epithelial inclusion into the alveolar socket. Case presentation: A 32-year-old male patient presented to the Oral Medicine service in the authors’ institution, with a chief complaint of left-sided facial swelling with slow growth and development for 2 years. Intra oral examination revealed a symptomatic circumscribed lesion of approximately 5–6 cm without mobility, firm on palpation, located in the vestibular sulcus on left-sided maxilla. It was situated in the region between teeth 25 to 27, with the teeth 26 being absent The lateral wall was surgically removed from the cystic cavity, followed by conservative decompression allowing gradual pneumatization of the maxillary sinus. The lesion response comprised regression in size, swelling, and pain, preserving the affected site and benefiting the patient with possible rehabilitation in the future. At the 2-year follow-up, the patient reported no complications. Conclusion: This study case demonstrated that MSM could be confused with tumors from an odontogenic nature, sometimes presenting an aggressive growth pattern. Although numerous treatment modalities exist for the treatment of MSM, the conservative technique promotes effective tissue preservation and benefits to the patient.

Background: We aimed to present a minimally invasive clinical approach to collect a suitable sample for the laboratory diagnosis of desquamative gingivitis. Materials and Methods: The proposed technique involves Nikolsky's test for the collection of tissue samples. It consists of the histopathological analysis of the bullous membrane formed in cases with positive Nikolsky's sign (NS). Three patients without a previous diagnosis of the disease agreed to undergo this protocol before a biopsy. Results: The diagnoses of the three cases reported here were mucous pemphigoid (MP), pemphigus vulgaris (PV), and lichen planus (LP). The tissue samples collected using this technique were sufficient to microscopically observe partial-thickness epithelium (diagnosing PV) or full-thickness epithelium (diagnosing MP). The diagnosis of LP was only possible by conventional biopsy. Conclusion: We observed, for different cases, some advantages of the proposed technique: minimally invasive, potentially superior to exfoliative cytology, easily performed, and with low costs.

Facial cosmetic procedures are on increasing demand, for plastic surgeons and dental professionals now-a-days. New techniques applied for the renewal offacial contours have become the first treatment option before surgical corrections. This case report highlights some of the risks related to such procedures, reporting a case of a painful fluctuating nodule in the midline of the vestibular sulcus, extending towards the upper lip. The patient mentioned a 2-year history of progression of the lesion. The nodule was 0.8 cm wide, well defined, with normal colour. The excisional biopsy was proposed with initial suspect of pleomorphic adenoma, or other soft tissue tumour. Microscopic evaluation of the excised lesion revealed a foreign body granuloma caused by multiple spherules of transparent synthetic material of uniform diameter, identified as Polymethylmetacrylate (PMMA). The patient then recalled that he underwent an aesthetic procedure of rhinoplasty with facial filling that he did not correlate with the symptoms.

O fibroma odontogênico periférico é uma massa relativamente rara, benigna, não encapsulada e gengival de tecido conjuntivo fibroso, considerada a contrapartida extra-óssea do fibroma odontogênico central. Ele foi anteriormente bastante comumente confundido com o fibroma ossificante periférico, até a classificação da OMS (1992), classificado em tumores odontogênicos. O objetivo deste artigo é relatar um caso de fibroma odontogênico periférico gigante de tipo rico em epitélio, avaliando e analisando, segundo a literatura, as suas características. Utilizou-se como ferramenta de diagnóstico a coloração Picrossírius vermelho em campo claro, luz polarizada e fluorescência, uma técnica histológica comumente usada para visualizar colágeno pela determinação da histoquímica da cor de polarização.

OBJECTIVE: The aim of this study was to compare two methodologies used in the evaluation of tissue response to root-end filling materials in rats. MATERIAL AND METHODS: Forty rats were divided into 4 groups: in Groups I and II (control groups), empty polyethylene tubes were implanted in the extraction site and in the subcutaneous tissue, respectively; in Groups III and IV, polyethylene tubes filled with ProRoot MTA were implanted in the extraction site and in the subcutaneous tissue, respectively. The animals were killed 7 and 30 days after tube implantation, and the hemi-maxillas and the capsular subcutaneous tissue, both with the tubes, were removed. Specimens were processed and evaluated histomorphologicaly under light microscopy. The scores obtained were analyzed statistically by the Kruskal-Wallis test (p

The purpose of this study was to evaluate morphological characteristics of teeth with hypercementosis that are relevant to endodontic practice. Twenty-eight extracted teeth with hypercementosis had their root apexes analyzed by scanning electron microscopy (SEM). The teeth were divided according to tooth groups and type of hypercementosis. The following aspects were examined under SEM: the contour and regularity of the root surface; presence of resorption; presence and number of apical foramina, and the diameter of the main foramen. The progression of club shape hypercementosis was directly associated with the presence of foramina and apical foramen obstruction. Cases of focal hypercementosis presented foramina on the surface, even when sidelong located in the root. Circular cementum hyperplasia form was present in 2 out of 3 residual roots, which was the highest proportion among the tooth types. The detection of a large number of foramina in the apical third of teeth with hypercementosis or even the possible existence of apical foramen obliteration contributes to understand the difficulties faced during endodontic treatment of these cases.

The present paper draw the attention of clinicians to investigate multiple slices of the computed tomography (CT) scan looking for a safe diagnosis of the so-called Garrè's osteomyelitis (GO) of jaws, a not uncommon disease characterized by astonishing bone growth. We report a case involving the left mandible of a 12-year-old girl presenting with a bony enlargement at left mandible. Initial examination revealed carious process of tooth 36 with radiographic apical rarefaction. However, we need to take care with this diagnosis because other aggressive diseases may cause bone enlargement mimicking GO. We observed here that careful examination of CT slices must be elucidative. In the present case, we observed the formation of a hypodense channel between periapical disease and the bone growth, through CT, thus supporting the pathophysiologic conditions for GO and allowing a safer decision to make the intervention restricted to tooth.

O objetivo deste trabalho foi fazer uma revisão de literatura sobre as características clínicas, radiográficas, diagnóstico diferencial, origem e tratamento do cisto dentígero, além de relatar um caso clínico. Os cistos dentígeros são mais freqüentes na maxila do que na mandíbula, geralmente acometendo principalmente a região anterior da maxila e posterior da mandíbula, associados a coroas de dentes retidos na sua porção cervical. As lesões são assintomáticas, não alcançando grandes proporções e clinicamente podem provocar expansão óssea, assimetria facial ou deformidade do local. No caso clínico apresentado, o exame radiográfico demonstrou o dente 23 incluso, radiolucência limitada por uma cortical óssea. A abordagem clínica foi realizada com enucleação cirúrgica e o exame histopatológico confirmou tratar-se de um cisto dentígero.