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1. Gamma-delta hepatosplenic T-cell lymphoma. Description of a case with immunophenotypic and molecular follow-up successfully treated with chemotherapy alone.

Author

Moleti, Maria Luisa, Testi, Anna Maria, Giona, Fiorina, Amendola, Angela, Palumbo, Giovanna, Uccini, Stefania, Starza, Irene Della, de Propris, Maria Stefania, Guarini, Anna, and Foà, Robin

Subjects
*LYMPHOMAS, *ANTINEOPLASTIC agents, *CANCER chemotherapy, *DRUG therapy, *RETICULOENDOTHELIAL granulomas, *ETOPOSIDE, *ONCOLOGY
Abstract

This study hereby reports the case of a 19-year old boy with a gamma-delta hepatosplenic T-cell lymphoma (HSTCL). Initial therapy consisted of four cycles of the IEV (Ifosphamide, Epirubicin and Etoposide) scheme. Further treatment strategy was then adapted according to minimal residual disease monitoring by immunophenotypic and T-cell receptor gamma chain gene evaluation. The patient remains in complete clinical, immunological and molecular remission and in good clinical conditions 48 months after diagnosis and 40 months after stopping therapy. [ABSTRACT FROM AUTHOR]

Published
2006
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