Search

Kaufman Domains of Creativity Scale (K-DOCS) is a self-report of creative behavior in five distinct domains. The present study aims to translate K-DOCS into Russian and evaluate its psychometric properties. The psychometric analysis was performed on a sample of adults recruited through Yandex Toloka (N = 1011; M[subscript age] = 35.94, SD[subscript age] = 10.95) from various regions of Russia and Commonwealth of Independent States (CIS) countries. Exploratory and confirmatory factor analyses indicated that the model with five correlated factors showed the best fit to empirical data. All factors demonstrated good internal consistency and moderate test-retest reliability. The correlation and hierarchical regression analyses for K-DOCS factors, creative achievements by CBI (Creative Behavior Inventory), and personality traits by BFI-2 (Big Five Inventory -- 2) yielded evidence for an adequate level of convergent and discriminant validity. We also examined differences across K-DOCS factors among occupations defined by Holland's typology and attempted to investigate K-DOCS measurement invariance across gender. As a result, we obtained evidence supporting the construct validity of K-DOCS and established its partial measurement invariance across gender. The current study shows that Russian K-DOCS has satisfactory psychometric properties and can serve as a trusted guide into various manifestations of humans' creative behavior.

Adenovirus vaccines, particularly the COVID-19 Ad5-nCoV adenovirus vaccine, have emerged as promising tools in the fight against infectious diseases. In this study, we investigated the structure of the T cell response to the Spike protein of the SARS-CoV-2 virus used in the COVID-19 Ad5-nCoV adenoviral vaccine in a phase 3 clinical trial (NCT04540419). In 69 participants, we collected peripheral blood samples at four time points after vaccination or placebo injection. Sequencing of T cell receptor repertoires from Spike-stimulated T cell cultures at day 14 from 17 vaccinated revealed a more diverse CD4+ T cell repertoire compared to CD8+. Nevertheless, CD8+ clonotypes accounted for more than half of the Spike-specific repertoire. Our longitudinal analysis showed a peak T cell response at day 14, followed by a decline untilmonth 6. Remarkably, multiple T cell clonotypes persisted for at least 6 months after vaccination, as demonstrated by ex vivo stimulation. Examination of CDR3 regions revealed homologous sequences in both CD4+ and CD8+ clonotypes, with major CD8+ clonotypes sharing high similarity with annotated sequences specific for the NYNYLYRLF peptide, suggesting potential immunodominance. In conclusion, our study demonstrates the immunogenicity of the Ad5-nCoV adenoviral vaccine and highlights its ability to induce robust and durable T cell responses. These findings provide valuable insight into the efficacy of the vaccine against COVID-19 and provide critical information for ongoing efforts to control infectious diseases. [ABSTRACT FROM AUTHOR]

Application of Josephson effect in sensors, electronic and metrological devices working at temperature of 77 K requires fabrication of efficient and reproducible high temperature superconducting (HTS) Josephson junctions. In order to enhance the performance of HTS junctions, we introduce multilayered approach to YBCO-based step-edge Josephson junction manufacture. Thin YBCO and multilayered YBCO/NdBCO/YBCO films of a similar thickness (\sim210 nm) were grown by a pulsed-laser deposition technique on MgO (100) substrates with artificially created step edge. Large discrepancies of Ic and Rn values were found between these two types of junction. Results of their structural and electrical properties are reported. [ABSTRACT FROM AUTHOR]