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The paper describes the derivation of finite-element models of one-dimensional fluid flows with heat transfer in pipes, using the Galerkin/least-squares approach. The models are first derived for one-phase flows, and then extended to homogeneous two-phase flows. The resulting equations have then been embedded in the context of object-oriented system modelling; this allows one to combine the fluid flow model with a model for other phenomena such as heat transfer, as well as with models of other discrete components such as pumps or valves, to obtain complex models of heat exchangers. The models are then validated by simulating a typical heat exchanger plant. [ABSTRACT FROM AUTHOR]

Abstract: Background: Axillary lymphadenectomy remains an integral part of breast cancer treatment, yet seroma formation occurs in 15% to 85% of cases. Among methods employed to reduce seroma magnitude and duration, fibrin glue has been proposed in numerous studies, with controversial results. Methods: Fifty patients underwent quadrantectomy or mastectomy with level I/II axillary lymphadenectomy; a suction drain was fitted in all patients. Fibrin glue spray and a collagen patch were applied to the axillary fossa in 25 patients; the other 25 patients were treated conventionally. Results: Suction drainage was removed between postoperative days 3 and 4. Seroma magnitude and duration were significantly reduced (P = .004 and .02, respectively) and there were fewer evacuative punctures in patients receiving fibrin glue and collagen patches compared with the conventional treatment group. Conclusions: Use of fibrin glue with collagen patches does not always prevent seroma formation, but it does reduce seroma magnitude and duration, as well as necessary evacuative punctures. [Copyright &y& Elsevier]