Search

The current and next observation seasons will detect hundreds of gravitational waves (GWs) from compact binary systems coalescence at cosmological distances. When combined with independent electromagnetic measurements, the source redshift will be known, and we will be able to obtain precise measurements of the Hubble constant H 0 via the distance–redshift relation. However, most observed mergers are not expected to have electromagnetic counterparts, which prevents a direct redshift measurement. In this scenario, one possibility is to use the dark sirens method that statistically marginalizes over all the potential host galaxies within the GW location volume to provide a probabilistic source redshift. Here we presented H 0 measurements using two new dark sirens compared to previous analyses using DECam data: GW190924 |$\_$| 021846 and GW200202 |$\_$| 154313. The photometric redshifts of the possible host galaxies of these two events are acquired from the DECam Local Volume Exploration Survey (DELVE) carried out on the Blanco telescope at Cerro Tololo. The combination of the H 0 posterior from GW190924 |$\_$| 021846 and GW200202 |$\_$| 154313 together with the bright siren GW170817 leads to |$H_{0} = 68.84^{+15.51}_{-7.74}\, \rm {km\, s^{-1}\, Mpc^{-1}}$|⁠. Including these two dark sirens improves the 68  per cent confidence interval (CI) by 7  per cent over GW170817 alone. This demonstrates that the addition of well-localized dark sirens in such analysis improves the precision of cosmological measurements. Using a sample containing 10 well-localized dark sirens observed during the third LIGO/Virgo observation run, without the inclusion of GW170817, we determine a measurement of |$H_{0} = 76.00^{+17.64}_{-13.45}\, \rm {km\, s^{-1}\, Mpc^{-1}}$|⁠. [ABSTRACT FROM AUTHOR]

The observed diversity in Type Ia supernovae (SNe Ia) – the thermonuclear explosions of carbon–oxygen white dwarf stars used as cosmological standard candles – is currently met with a variety of explosion models and progenitor scenarios. To help improve our understanding of whether and how often different models contribute to the occurrence of SNe Ia and their assorted properties, we present a comprehensive analysis of seven nearby SNe Ia. We obtained one to two epochs of optical spectra with Gemini Observatory during the nebular phase (>200 d past peak) for each of these events, all of which had time series of photometry and spectroscopy at early times (the first ∼8 weeks after explosion). We use the combination of early- and late-time observations to assess the predictions of various models for the explosion (e.g. double-detonation, off-centre detonation, stellar collisions), progenitor star (e.g. ejecta mass, metallicity), and binary companion (e.g. another white dwarf or a non-degenerate star). Overall, we find general consistency in our observations with spherically symmetric models for SN Ia explosions, and with scenarios in which the binary companion is another degenerate star. We also present an in-depth analysis of SN 2017fzw, a member of the subgroup of SNe Ia which appear to be transitional between the subluminous '91bg-like' events and normal SNe Ia, and for which nebular-phase spectra are rare. [ABSTRACT FROM AUTHOR]

The origin of the diverse light-curve shapes of Type II supernovae (SNe), and whether they come from similar or distinct progenitors, has been actively discussed for decades. Here, we report spectropolarimetry of two fast declining Type II (Type IIL) SNe: SN 2013ej and SN 2017ahn. SN 2013ej exhibited high continuum polarization from very soon after the explosion to the radioactive tail phase with time-variable polarization angles. The origin of this polarimetric behaviour can be interpreted as the combination of two different aspherical structures, namely an aspherical interaction of the SN ejecta with circumstellar matter (CSM) and an inherently aspherical explosion. Aspherical explosions are a common feature of slowly declining Type II (Type IIP) SNe. By contrast, SN 2017ahn showed low polarization not only in the photospheric phase but also in the radioactive tail phase. This low polarization in the tail phase, which has never before been observed in other Type IIP/L SNe, suggests that the explosion of SN 2017ahn was nearly spherical. These observations imply that Type IIL SNe have, at least, two different origins: they result from stars that have different explosion properties and/or different mass-loss processes. This fact might indicate that 13ej-like Type IIL SNe originate from a similar progenitor to those of Type IIP SNe accompanied by an aspherical CSM interaction, while 17ahn-like Type IIL SNe come from a more massive progenitor with less hydrogen in its envelope. [ABSTRACT FROM AUTHOR]

We present photometry, spectra, and spectropolarimetry of supernova (SN) 2014ab, obtained through ∼200 d after peak brightness. SN 2014ab was a luminous Type IIn SN (MV < −19.14 mag) discovered after peak brightness near the nucleus of its host galaxy, VV 306c. Pre-discovery upper limits constrain the time of explosion to within 200 d prior to discovery. While SN 2014ab declined by ∼1 mag over the course of our observations, the observed spectrum remained remarkably unchanged. Spectra exhibit an asymmetric emission-line profile with a consistently stronger blueshifted component, suggesting the presence of dust or a lack of symmetry between the far side and near side of the SN. The Pa β emission line shows a profile very similar to that of H α, implying that this stronger blueshifted component is caused either through obscuration by large dust grains, occultation by optically thick material, or a lack of symmetry between the far side and near side of the interaction region. Despite these asymmetric line profiles, our spectropolarimetric data show that SN 2014ab has little detected polarization after accounting for the interstellar polarization. We are likely seeing emission from a photosphere that has only small deviation from circular symmetry in the plane normal to our line of sight, but with either large-grain dust or significant asymmetry in the density of circumstellar material or SN ejecta along our line of sight. We suggest that SN 2014ab and SN 2010jl (as well as other SNe IIn) may be events with similar geometry viewed from different directions. [ABSTRACT FROM AUTHOR]

We present late-time spectra of eight Type Ia supernovae (SNe Ia) obtained at >200 d after peak brightness using the Gemini South and Keck telescopes. All of the SNe Ia in our sample were nearby, well separated from their host galaxy's light, and have early-time photometry and spectroscopy from the Las Cumbres Observatory. Parameters are derived from the light curves and spectra such as peak brightness, decline rate, photospheric velocity and the widths and velocities of the forbidden nebular emission lines. We discuss the physical interpretations of these parameters for the individual SNe Ia and the sample in general, including comparisons to well-observed SNe Ia from the literature. There are possible correlations between early-time and late-time spectral features that may indicate an asymmetric explosion, so we discuss our sample of SNe within the context ofmodels for an offset ignition and/or white dwarf collisions. A subset of our late-time spectra are uncontaminated by host emission, and we statistically evaluate our non-detections of Hα emission to limit the amount of hydrogen in these systems. Finally, we consider the late-time evolution of the iron emission lines, finding that not all of our SNe follow the established trend of a redward migration at >200 d after maximum brightness. [ABSTRACT FROM AUTHOR]

Copyright of Anaesthesist is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

We present multi-epoch near-infrared observations of Nova Ophiuchi 2015 which was discovered during outburst in March 2015. This nova showed a few special properties viz. (i) it displayed an unusual prolonged flat-top light curve which does not easily fit into known classes of nova light curves, (ii) it showed evidence for possessing an evolved secondary in the outbursting binary system, and (iii) it made a rare reverse hybrid transition from the He/N class to Fe II class early during its outburst. The present studies focus on the spectroscopic evolution of the object around maximum light and early decline. We show that there was a unique, rapid strengthening and decline in the He 1.0831, 2.0581 µm line strengths during this stage, wherein the nova combined the traits of both the He/N and Fe II classes. Possible causes for this behaviour are discussed. The relative strengths of the Lyβ fluoresced OI 0.8446, 1.1287 µm lines are used to estimate the reddening to the nova. A recombination Case B analysis of the early spectra is used to set constraints on the electron density and emission measure, and a later time spectrum when the ejecta were optically thin is used to estimate the ejecta mass to be (0.95-1.9) × 10-4 M⊙. Power-law fits made to study the evolution of the continuum, show a fairly constant slope which differs from the trend generally expected during a nova's evolution viz. beginning with a blackbody and evolving to a free-free distribution at later stages. [ABSTRACT FROM AUTHOR]

High-quality collections of Type II supernova (SN) light curves are scarce because they evolve for hundreds of days, making follow-up observations time consuming and often extending over multiple observing seasons. In light of these difficulties, the diversity of SNe II is not fully understood. Here we present ultraviolet and optical photometry of 12 SNe II monitored by the Las Cumbres Observatory Global Telescope Network during 2013 to 2014, and compare them with previously studied SNe having well-sampled light curves. We explore SN II diversity by searching for correlations between the slope of the linear light-curve decay after maximum light (historically used to divide SNe II into IIL and IIP) and other measured physical properties. While SNe IIL are found to be on average more luminous than SNe IIP, SNe IIL do not appear to synthesize more 56Ni than SNe IIP. Finally, optical nebular spectra obtained for several SNe in our sample are found to be consistent with models of red supergiant progenitors in the 12-16 M range. Consequently, SNe IIL appear not to account for the deficit of massive red supergiants as SN II progenitors. [ABSTRACT FROM AUTHOR]

SN 2012dn is a super-Chandrasekhar mass candidate in a purportedly normal spiral (SAcd) galaxy, and poses a challenge for theories of type Ia supernova diversity. Here we utilize the fast and highly parametrized spectrum synthesis tool, SYNAPPS, to estimate relative expansion velocities of species inferred from optical spectra obtained with six facilities. As with previous studies of normal SN Ia, we find that both unburned carbon and intermediate-mass elements are spatially coincident within the ejecta near and below 14 000 km s-1. Although the upper limit on SN 2012dn's peak luminosity is comparable to some of the most luminous normal SN Ia, we find a progenitor mass exceeding ~1.6 M⊙ is not strongly favoured by leading merger models since these models do not accurately predict spectroscopic observations of SN 2012dn and more normal events. In addition, a comparison of light curves and host-galaxy masses for a sample of literature and Palomar Transient Factory SN Ia reveals a diverse distribution of SN Ia subtypes where carbon-rich material remains unburned in some instances. Such events include SN 1991T, 1997br, and 1999aa where trace signatures of C III at optical wavelengths are presumably detected. [ABSTRACT FROM AUTHOR]

We present multiepoch near-infrared photospectroscopic observations of Nova Cephei 2014 and Nova Scorpii 2015, discovered in outburst on 2014 March 8.79 UT and 2015 February 11.84 UT, respectively. Nova Cep 2014 shows the conventional NIR characteristics of a Fe II class nova characterized by strong C I, HI and OI lines, whereas Nova Sco 2015 is shown to belong to the He/N class with strong He I, HI and OI emission lines. The highlight of the results consists in demonstrating that Nova Sco 2015 is a symbiotic system containing a giant secondary. Leaving aside the T CrB class of recurrent novae, all of which have giant donors, Nova Sco 2015 is shown to be only the third classical nova to be found with a giant secondary. The evidence for the symbiotic nature is threefold; first is the presence of a strong decelerative shock accompanying the passage of the nova's ejecta through the giant's wind, second is the H a excess seen from the system and third is the spectral energy distribution of the secondary in quiescence typical of a cool late-type giant. The evolution of the strength and shape of the emission line profiles shows that the ejecta velocity follows a power-law decay with time (t-1.13±0.17). A Case B recombination analysis of the HI Brackett lines shows that these lines are affected by optical depth effects for both the novae. Using this analysis, we make estimates for both the novae of the emission measure n²eL, the electron density ne and the mass of the ejecta. [ABSTRACT FROM AUTHOR]

We hypothesize that at least some of the recently discovered class of calcium-rich gap transients are tidal detonation events of white dwarfs (WDs) by black holes (BHs) or possibly neutron stars. We show that the properties of the calcium-rich gap transients agree well with the predictions of the tidal detonation model. Under the predictions of this model, we use a follow-up X-ray observation of one of these transients, SN 2012hn, to place weak upper limits on the detonator mass of this system that include all intermediate-mass BHs (IMBHs). As these transients are preferentially in the stellar haloes of galaxies, we discuss the possibility that these transients are tidal detonations of WDs caused by random flyby encounters with IMBHs in dwarf galaxies or globular clusters. This possibility has been already suggested in the literature but without connection to the calcium-rich gap transients. In order for the random flyby cross-section to be high enough, these events would have to be occurring inside these dense stellar associations. However, there is a lack of evidence for IMBHs in these systems, and recent observations have ruled out all but the very faintest dwarf galaxies and globular clusters for a few of these transients. Another possibility is that these are tidal detonations caused by three-body interactions, where a WD is perturbed towards the detonator in isolated multiple star systems. We highlight a number of ways this could occur, even in lower mass systems with stellar-mass BHs or neutron stars. Finally, we outline several new observational tests of this scenario, which are feasible with current instrumentation. [ABSTRACT FROM AUTHOR]

We present near-infrared (NIR) time-series spectroscopy, as well as complementary ultraviolet (UV), optical, and NIR data, of the Type Ia supernova (SN Ia) iPTF13ebh, which was discovered within two days from the estimated time of explosion. The first NIR spectrum was taken merely 2.3 days after explosion and may be the earliest NIR spectrum yet obtained of a SN Ia. The most striking features in the spectrum are several NIR CI lines, and the CI λ1.0693 Δm line is the strongest ever observed in a SN Ia. Interestingly, no strong optical CII counterparts were found, even though the optical spectroscopic time series began early and is densely-cadenced. Except at the very early epochs, within a few days from the time of explosion, we show that the strong NIR CI compared to the weaker optical CII appears to be general in SNe Ia. iPTF13ebh is a fast decliner with Δm15(B) = 1.79 ± 0.01, and its absolute magnitude obeys the linear part of the width-luminosity relation. It is therefore categorized as a "transitional" event, on the fast-declining end of normal SNe Ia as opposed to subluminous/91bg-like objects. iPTF13ebh shows NIR spectroscopic properties that are distinct from both the normal and subluminous/91bg-like classes, bridging the observed characteristics of the two classes. These NIR observations suggest composition and density of the inner core similar to that of 91bg-like events, and a deep reaching carbon burning layer not observed in slower declining SNe Ia. There is also a substantial difference between the explosion times inferred from the early-time light curve and the velocity evolution of the SiII λ0.6355 Δm line, implying a long dark phase of ~4 days. [ABSTRACT FROM AUTHOR]

We present multiband ultraviolet and optical light curves, as well as visual-wavelength and near-infrared spectroscopy of the Type II linear (IIL) supernova (SN) 2013by. We show that SN 2013by and other SNe IIL in the literature, after their linear decline phase that start after maximum, have a sharp light-curve decline similar to that seen in SNe IIP. This light-curve feature has rarely been observed in other SNe IIL due to their relative rarity and the intrinsic faintness of this particular phase of the light curve. We suggest that the presence of this drop could be used as a physical parameter to distinguish between subclasses of SNe II, rather than their light-curve decline rate shortly after peak. Close inspection of the spectra of SN 2013by indicate asymmetric line profiles and signatures of high-velocity hydrogen. Late (~90 d after explosion) near-infrared spectra of SN 2013by exhibit oxygen lines, indicating significant mixing within the ejecta. From the late-time light curve, we estimate that 0.029 M⊙ of 56Ni was synthesized during the explosion. It is also shown that the V-band light-curve slope is responsible for part of the scatter in the luminosity (V magnitude 50 d after explosion) versus 56Ni relation. Our observations of SN 2013by and other SNe IIL through the onset of the nebular phase indicate that their progenitors are similar to those of SNe IIP. [ABSTRACT FROM AUTHOR]

SN 2014J in M82 is the closest detected Type Ia supernova (SN Ia) in at least 28 yr and perhaps in 410 yr. Despite its small distance of 3.3 Mpc, SN 2014J is surprisingly faint, peaking at V = 10.6 mag, and assuming a typical SN Ia luminosity, we infer an observed visual extinction of AV = 2.0 ± 0.1 mag. But this picture, with RV = 1.6 ± 0.2, is too simple to account for all observations. We combine 10 epochs (spanning a month) of HST/Space Telescope Imaging Spectrograph (STIS) ultraviolet through near-infrared spectroscopy with HST/Wide Field Camera 3 (WFC3), Katzman Automatic Imaging Telescope, and FanCam photometry from the optical to the infrared and nine epochs of high-resolution TRES (Tillinghast Reflection Echelle Spectrograph) spectroscopy to investigate the sources of extinction and reddening for SN 2014J. We argue that the wide range of observed properties for SN 2014J is caused by a combination of dust reddening, likely originating in the interstellar medium of M82, and scattering off circumstellar material. For this model, roughly half of the extinction is caused by reddening from typical dust (E(B − V) = 0.45 mag and RV = 2.6) and roughly half by scattering off Large Magellanic Cloud-like dust in the circumstellar environment of SN 2014J. [ABSTRACT FROM PUBLISHER]

ABSTRACT We analyse deep g′ and r′ band data of 97 galaxy clusters imaged with MegaCam on the Canada-France-Hawaii telescope. We compute the number of luminous (giant) and faint (dwarf) galaxies using criteria based on the definitions of de Lucia et al. Due to excellent image quality and uniformity of the data and analysis, we probe the giant-to-dwarf ratio (GDR) out to z ∼ 0.55. With X-ray temperature ( Tx) information for the majority of our clusters, we constrain, for the first time, the Tx-corrected giant and dwarf evolution separately. Our measurements support an evolving GDR over the redshift range 0.05 ≤ z ≤ 0.55. We show that modifying the ( g′ − r′) [ABSTRACT FROM AUTHOR]

We present a statistical analysis of a sample of 20 strong lensing clusters drawn from the Local Cluster Substructure Survey, based on high-resolution Hubble Space Telescope imaging of the cluster cores and follow-up spectroscopic observations using the Keck-I telescope. We use detailed parametrized models of the mass distribution in the cluster cores, to measure the total cluster mass and fraction of that mass associated with substructures within . These measurements are compared with the distribution of baryons in the cores, as traced by the old stellar populations and the X-ray emitting intracluster medium. Our main results include: (i) the distribution of Einstein radii is lognormal, with a peak and 1σ width of ; (ii) we detect an X-ray/lensing mass discrepancy of at 3σ significance – clusters with larger substructure fractions displaying greater mass discrepancies, and thus greater departures from hydrostatic equilibrium and (iii) cluster substructure fraction is also correlated with the slope of the gas density profile on small scales, implying a connection between cluster–cluster mergers and gas cooling. Overall our results are consistent with the view that cluster–cluster mergers play a prominent role in shaping the properties of cluster cores, in particular causing departures from hydrostatic equilibrium, and possibly disturbing cool cores. Our results do not support recent claims that large Einstein radius clusters present a challenge to the cold dark matter paradigm. [ABSTRACT FROM AUTHOR]

Background: Procalcitonin (PCT) is an established laboratory marker for disease severity in patients with infection and sepsis. In addition, PCT has been shown to be an effective marker for a limited number of localized infections. However, whether or not PCT has any diagnostic value for acute appendicitis, still remains unclear. The purpose of this prospective bicenter study was, therefore, to determine whether or not the PCT levels in the serum of patients with acute appendicitis have any diagnostic value. Methods: This prospective study included 103 patients who received an appendectomy, based on the clinical diagnosis of acute appendicitis, in a surgical department of an academic teaching hospital in Germany or in a county hospital in Spain. White blood cell count (WBC), C-reactive protein (CRP) and procalcitonin (PCT) values were determined preoperatively. All appendectomy specimens were sent for routine histopathological evaluation. Based on this information, the patients were assigned to 1 of 5 groups that reflected the severity of the appendicitis. Results: Of the 103 patients who were included in the study, 98 had appendicitis. Fourteen (14.3%) showed an increase in PCT values. Of those 14, 4 had a serum PCT >0.5 ng/ml, 9 had a PCT value >2–10 ng/ml and 1 had a PCT value >10 ng/ml. The sensitivity of PCT was calculated to be 0.14. The mean WBC value was 13.0/nl (± 5.2, 3.4–31), and for CRP it was 8.8 mg/dl (± 13, 0–60.2). The values of CRP, WBC and PCT increased with the severity of the appendicitis. Conclusions: PCT is potentially increased in rare cases of severe inflammation and, in particular, after appendiceal perforation or gangrenous appendicitis. However, its remarkably low sensitivity prohibits its routine use for the diagnosis of appendicitis. Copyright © 2009 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Reports the effect of Notch1 on glucocorticoid-induced apoptosis of thymocytes. Restoration of GC sensitivity in thymocytes expressing NothIC by transgenic SRG3 expression; Differentiation of double positive into single positive; Stimulation of the T cell receptor signaling pathway.

We report on our discovery and observations of the Pan-STARRS1 supernova (SN) PS1-12sk, a transient with properties that indicate atypical star formation in its host galaxy cluster or pose a challenge to popular progenitor system models for this class of explosion. The optical spectra of PS1- 12sk classify it as a Type Ibn SN (c.f. SN 2006jc), dominated by intermediate-width (3×103 km s−1) and time variable He I emission. Our multi-wavelength monitoring establishes the rise time dt ∼ 9 − 23 days and shows an NUV-NIR SED with temperature & 17 × 103 K and a peak magnitude of Mz = −18.88 ± 0.02 mag. SN Ibn spectroscopic properties are commonly interpreted as the signature of a massive star (17 − 100 M⊙) explosion within a He-enriched circumstellar medium. However, unlike previous Type Ibn supernovae, PS1-12sk is associated with an elliptical brightest cluster galaxy, CGCG 208-042 (z = 0.054) in cluster RXC J0844.9+4258. The expected probability of an event like PS1-12sk in such environments is low given the measured infrequency of core-collapse SNe in red sequence galaxies compounded by the low volumetric rate of SN Ibn. Furthermore, we find no evidence of star formation at the explosion site to sensitive limits (ΣHα . 2×10−3 M⊙ yr−1 kpc−2). We therefore discuss white dwarf binary systems as a possible progenitor channel for SNe Ibn. We conclude that PS1-12sk represents either a fortuitous and statistically unlikely discovery, evidence for a top-heavy IMF in galaxy cluster cooling flow filaments, or the first clue suggesting an alternate progenitor channel for Type Ibn SNe., Astronomy

Las Cumbres Observatory Global Telescope Network (LCOGT) is currently building a new kind of general-purpose astronomical facility: a fully robotic network of telescopes of 2m, 1m and 0.4m apertures and homogeneous instrumentation. A pan-network approach to scheduling (rather than per individual telescope) offers redundancy in the event of poor weather or technical failure, as well as the ability to observe a target around the clock. Here we describe the network design and instrumentation under development, together with the main science programmes already being lead by LCOGT staff. [ABSTRACT FROM PUBLISHER]

Methyl ester of [U-C]5,11,14-20∶3 was administered to essential fatty acid deficient rats. In contrast to a report by Takagi, it was found that the trienoic acid was not converted into arachidonic acid. [ABSTRACT FROM AUTHOR]

Abstract Skin diseases on the nose are seen in a variety of medical disciplines. Dermatologists, otorhinolaryngologists, general practitioners and general plastic and dermatologic surgeons are regularly consulted regarding cutaneous lesions on the nose. This article is the second part of a review series dealing with cutaneous lesions on the head and face, which are frequently seen in daily practice by a dermatologic surgeon. In this review, we focus on those skin diseases on the nose where surgery or laser therapy is considered a possible treatment option or that can be surgically evaluated.

Abstract Introduction Epiploic appendagitis is a rare cause of focal abdominal pain which, depending on its localisation, can mimic a variety of abdominal diseases. We describe a patient with an inflamed necrotic appendix epiploicum with immediate contact to a non-inflamed appendix vermiformis mimicking acute appendicitis. Considering the rare localization, this is the first report of this kind in the literature. Case presentation We present the case of a 50-year-old Caucasian man who presented with classic signs of acute appendicitis. On clinical exam, McBurney and Blumberg signs were positive. Additionally he had fever, leucocytosis (12/nl) and a slight increase in C-reactive protein (1 mg/dl). Based on the clinical presentation, the patient was taken to the operating room to perform an appendicectomy. Surprisingly, we found an inflamed necrotic appendix epiploicum, located immediately on a non-inflamed appendix vermiformis, which was ligated and excised. Conclusion This case report demonstrates that epiploic appendagitis can mimic acute appendicitis on clinical exam and should be considered in the broad spectrum of abdominal disease presenting with right lower quadrant pain.

Abstract Skin diseases on the external aspect of the ear are seen in a variety of medical disciplines. Dermatologists, othorhinolaryngologists, general practitioners, general and plastic surgeons are regularly consulted regarding cutaneous lesions on the ear. This article will focus on those diseases wherefore surgery or laser therapy is considered as a possible treatment option or which are potentially subject to surgical evaluation.

Abstract Background Epiploic appendagitis (EA) is a rare cause of focal abdominal pain in otherwise healthy patients with mild or absent secondary signs of abdominal pathology. It can mimick diverticulitis or appendicitis on clinical exam. The diagnosis of EA is very infrequent, due in part to low or absent awareness among general surgeons. The objective of this work was to review the authors' experience and describe the clinical presentation of EA. Methods All patients diagnosed with EA between January 2004 and December 2006 at an urban surgical emergency room were retrospectively reviewed by two authors in order to share the authors' experience with this rare diagnosis. The operations were performed by two surgeons. Pathological examinations of specimens were performed by a single pathologist. A review of clinical presentation is additionally undertaken. Results Ten patients (3 females and 7 males, average age: 44.6 years, range: 27–76 years) were diagnosed with symptomatic EA. Abdominal pain was the leading symptom, the pain being localized in the left (8 patients, 80 %) and right (2 patients, 20%) lower quadrant. All patients were afebrile, and with the exception of one patient, nausea, vomiting, and diarrhea were not present. CRP was slightly increased (mean: 1.2 mg/DL) in three patients (33%). Computed tomography findings specific for EA were present in five patients. Treatment was laparoscopic excision (n = 8), excision via conventional laparotomy (n = 1) and conservative therapy (n = 1). Conclusion In patients with localized, sharp, acute abdominal pain not associated with other symptoms such as nausea, vomiting, fever or atypical laboratory values, the diagnosis of EA should be considered. Although infrequent up to date, with the increase of primary abdominal CT scans and ultrasound EA may well be diagnosed more frequently in the future.

Abstract Keloids are defined as dermal fibrotic lesions which are considered an aberration of the wound healing process. Their etiology and pathogenesis are poorly understood. Different treatment modalities are described in the literature depending on the morphology and size of the keloid. We report a case of a large ear keloid on the helical rim which was successfully treated with surgery and a custom designed silicon pressure clip.

Abstract Background Medullary thyroid carcinomas (MTC) constitute about 5 to 7 % of thyroid neoplasms. They originate from parafollicular C cells which produce Calcitonin, a hormone which has an impact on calcium metabolism and represents the biochemical activity of MTC. In rare cases pre-operative serum calcitonin can be negative. Case presentation We report on a 73-year-old female patient with a rare case of a serum calcitonin negative medullary thyroid carcinoma who suffered fulminant post-operative course and died of multiple metastasis. Conclusion This case shows that in very rare cases MTCs do not secrete calcitonin making diagnosis and tumour follow-up difficult. To this date, only few reports describing this combination of circumstances were found in the English literature.