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Background Ventricular repolarization (VR) increases the risk of sudden cardiac death due to ventricular arrhythmia. We aimed to evaluate the blood pressure (BP) parameters affecting VR in obese children. Methods Obese (BMI [greater than or equal to] 95p) and healthy children [greater than or equal to] 120 cm between January 2017 and June 2019 were included. Demographic and laboratory data, peripheral and central BPs evaluated by a device capable of ambulatory blood pressure monitoring (ABPM), and pulse wave analysis were assessed. Electrocardiographic ventricular repolarization indices, left ventricular mass index (LVMI), and relative wall thickness (RWT) were calculated. Results A total of 52 obese and 41 control patients were included. Uric acid, triglyceride, total cholesterol, LDL, and ALT values, systolic and diastolic office BPs, 24-h, daytime and nighttime systolic and mean arterial BPs, daytime diastolic BP SDS levels, daytime and nighttime systolic loads, daytime diastolic load, 24-h, daytime and nighttime central systolic and diastolic BPs, and pulse wave velocity values were significantly higher, whereas 24-h, daytime and nighttime AIx@75 were similar between the groups. fT4 levels of obese cases were significantly lower. QTcd and Tp-ed were higher in obese patients. Although RWT was higher in obese cases, LVMI values and cardiac geometry classifications were similar. The independent factors affecting VR in obese cases were younger age and higher diastolic load at night (B = - 2.83, p = 0.010; B = 0.257, p = 0.007, respectively). Conclusion Obese patients have higher peripheral and central BP, arterial stiffness, and higher VR indices that develop before an increase in LVMI. It would be useful to prevent obesity from an early age and follow up nighttime diastolic load to control VR associated sudden cardiac death in obese children. Graphical abstract, Author(s): Belde Kasap Demir [sup.1] [sup.2] , Eren Soyaltin [sup.1] [sup.2] , Caner Alparslan [sup.3] , Tülay Demircan [sup.4] , Seçil Arslansoyu Çamlar [sup.2] [sup.5] , Demet Alaygut [sup.2] [sup.5] [...]

Author(s): Özgür Özdemir-Simsek [sup.1] , Belde Kasap-Demir [sup.1] [sup.2] , Gökçen Erfidan [sup.1] , Seçil Arslansoyu-Çamlar [sup.1] , Eren Soyaltin [sup.1] , Demet Alaygut [sup.1] , Fatma Mutlubas [sup.1] Author [...]

Author(s): Demet Alaygut [sup.1] , Gökçen Erfidan [sup.1] , Eren Soyaltin [sup.1] , Zuhal Önder Sivis [sup.2] , Seçil Arslansoyu Çamlar [sup.1] , Fatma Mutlubas [sup.1] , Belde Kasap Demir [...]

Author(s): Özgür Özdemir-Simsek [sup.1] , Seçil Arslansoyu-Çamlar [sup.1] , Hüseyin Üstün [sup.2] , Irem Nur Nur Ingenç [sup.3] , Gökçen Erfidan [sup.1] , Eren Soyaltin [sup.1] , Melek Akar [sup.2] [...]

Author(s): Eren Soyaltin [sup.1] , Seçil Arslansoyu Çamlar [sup.1] , Demet Alaygut [sup.1] , Fatma Mutlubas [sup.1] , Önder Yavascan [sup.1] , Seyhun Solakoglu [sup.2] , Belde Kasap Demir [sup.1] [...]

Author(s): Gökçen Erfidan [sup.1] , Demet Alaygut [sup.1] , Eren Soyaltin [sup.1] , Cemaliye Basaran [sup.1] , Seçil Arslansoyu Çamlar [sup.1] , Fatma Mutlubas [sup.1] , Belde Kasap Demir [sup.1] [...]

Author(s): Eren Soyaltin [sup.1] , Belde Kasap Demir [sup.1] [sup.2] , Gökçen Erfidan [sup.1] , Seçil Arslansoyu Çamlar [sup.1] , Demet Alaygut [sup.1] , Fatma Mutlubas [sup.1] Author Affiliations: (1) [...]

Author(s): Eren Soyaltin [sup.1] , Belde Kasap-Demir [sup.1] [sup.2] , Caner Alparslan [sup.1] , Seçil Arslansoyu-Çamlar [sup.1] , Elif Perihan Öncel [sup.3] , Özgür Kirbiyik [sup.4] , Demet Alaygut [sup.1] [...]

Author(s): Özgür Özdemir-Simsek [sup.1] , Belde Kasap-Demir [sup.1] [sup.2] , Gökçen Erfidan [sup.1] , Seçil Arslansoyu-Çamlar [sup.1] , Eren Soyaltin [sup.1] , Demet Alaygut [sup.1] , Fatma Mutlubas [sup.1] Author [...]

Author(s): Demet Alaygut [sup.1] , Gökçen Erfidan [sup.1] , Eren Soyaltin [sup.1] , Zuhal Önder Sivis [sup.1] , Seçil Arslansoyu Çamlar [sup.1] , Fatma Mutlubas [sup.1] , Belde Kasap Demir [...]

Author(s): Özgür Özdemir-Simsek [sup.1] , Seçil Arslansoyu-Çamlar [sup.1] , Hüseyin Üstün [sup.1] , Irem Nur Ingenç [sup.2] , Gökçen Erfidan [sup.1] , Eren Soyaltin [sup.1] , Melek Akar [sup.1] , [...]

Author(s): Eren Soyaltin [sup.1] , Seçil Arslansoyu Çamlar [sup.1] , Demet Alaygut [sup.1] , Fatma Mutlubas [sup.1] , Önder Yavascan [sup.1] , Seyhun Solakoglu [sup.2] , Belde Kasap Demir [sup.1] [...]

Author(s): Gökçen Erfidan [sup.1] , Demet Alaygut [sup.1] , Eren Soyaltin [sup.1] , Cemaliye Basaran [sup.1] , Seçil Arslansoyu Çamlar [sup.1] , Fatma Mutlubas [sup.1] , Belde Kasap Demir [sup.1] [...]

Aim Urinary tract infections (UTIs) represent a common febrile illness in infancy. The study compared two UTI guidelines in terms of number of imaging studies, presence of parenchymal damage and radiation exposure in patients with the first febrile UTI between 2 and 24 months of age. Method The results of Tepecik UTI Guideline-1 used until 2012 (Group 1, n  = 105) were retrospectively compared with Tepecik UTI Guideline-2 (Group 2) used after 2013. In Group 1, urinary tract ultrasonography (US), dimercaptosuccinic acid (DMSA) and voiding cystourethrography (VCUG) were made in all patients. In Group 2, if the US result was abnormal, patients were evaluated with VCUG and DMSA. If the US was normal, only DMSA was performed. If the DMSA was abnormal, the VCUG was undergone (n : 43, 40.9%). Results The abnormal VCUG detection rate was 69.2% in Group 1 and 30.8% in Group 2 (p  = 0.09). Sensitivity and specificity of US in the diagnosis of vesicoureteral reflux (VUR) was 15.9% and 96.7% in Group 1 and 61.5% and 70.5% in Group 2, respectively. Abnormal DMSA findings were observed among 33.3% (Groups 1) and 66.7% (Groups 2) subjects, respectively (p  > 0.05). The median radiation exposure (500 mrem) of patients in Group 1 was statistically significantly higher than those in Group 2 (200 mrem) (p  < 0.001). Conclusion The VCUG should not be the first examination to be considered in such patients. We think that Tepecik UTI Guideline-2 reduces unnecessary invasive procedure and radiation exposure and not missed VUR in the management of children with UTI at 2–24 months. Needs prospective follow-up studies before considering this recommendation. [ABSTRACT FROM AUTHOR]

Author(s): Eren Soyaltin [sup.1] , Belde Kasap Demir [sup.1] [sup.2] , Gökçen Erfidan [sup.1] , Seçil Arslansoyu Çamlar [sup.1] , Demet Alaygut [sup.1] , Fatma Mutlubas [sup.1] Author Affiliations: (1) [...]

Author(s): Eren Soyaltin [sup.1] , Belde Kasap-Demir [sup.1] [sup.2] , Caner Alparslan [sup.1] , Seçil Arslansoyu-Çamlar [sup.1] , Elif Perihan Öncel [sup.3] , Özgür Kirbiyik [sup.4] , Demet Alaygut [sup.1] [...]

Copyright of Journal of Pediatric Disease / Türkiye Çocuk Hastalıkları Dergisi is the property of Turkish Journal of Pediatric Disease and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background/aim: In children with autosomal dominant polycystic kidney disease (ADPKD), clinical manifestations range from severe neonatal presentation to renal cysts found by chance. We aimed to evaluate demographic, clinical, laboratory findings, and genetic analysis of children with ADPKD. Materials and methods: We evaluated children diagnosed with ADPKD between January 2006 and January 2019. The diagnosis was established by family history, ultrasound findings, and/or genetic analysis. The demographic, clinical, and laboratory findings were evaluated retrospectively. Patients <10 years and ≥10 years at the time of diagnosis were divided into 2 groups and parameters were compared between the groups. Results: There were 41 children (M/F: 18/23) diagnosed with ADPKD. The mean age at diagnosis was 7.2 ± 5.1 (0.6-16.9) years and the follow-up duration was 59.34 ± 40.56 (8-198) months. Five patients (12%) were diagnosed as very early onset ADPKD. All patients had a positive family history. Genetic analysis was performed in 29 patients (PKD1 mutations in 21, PKD2 mutations in 1, no mutation in 3). Cysts were bilateral in 35 (85%) of the patients. Only one patient had hepatic cysts. No valvular defect was defined in 12 patients detected. Only 1 patient had hypertension. None of them had chronic kidney disease. No difference could be demonstrated in sex, laterality of the cysts, maximum cyst diameter, cyst or kidney enlargement, follow-up duration, or GFR at last visit between Groups 1 and 2. Conclusion: The majority of children with ADPKD had preserved renal functions and slight cyst enlargement during their follow-up. However, they may have different renal problems deserving closed follow-up. [ABSTRACT FROM AUTHOR]

Home hemodialysis (HD) has been supported by health authorities in many countries due to its nature of providing more freedom to the patients and the possibility to individualize the treatment. The treatment method is notable as a feasible dialysis option due to increase in life quality and improvement in the clinical findings of patients. However, pediatric home HD (HHD) is infrequently performed. In this study, we aimed to share our first year experience with HHD in a 15-year-old male patient. A 15-year-old male patient who had been receiving chronic peritoneal dialysis (CPD) for 13 years due to ESRD was transferred to chronic HD treatment due to treatment-resistant hypervolemia, hypertension, anemia and hyperphosphatemia associated with CPD failure. The education period was started with the consent of patient and his family and no problem was observed except short-term fear during the entry of a needle. Following the education period in the hospital, the treatment of the patient was continued at home. At the end of the first year of HHD treatment, increase in growth percentile and academic success, regression in the symptoms related to uremia, and also decrease in the use of medication and hospitalization were observed. Our patient felt better and had increased appetite, better growth scores and higher academic success, indicating that HHD could be a successful renal replacement treatment technique with its control of uremia-related symptoms and the decrease in medication needs of the patient. [ABSTRACT FROM AUTHOR]