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To assess the accuracy and stability of iris-registered femtosecond laser-assisted anterior capsule axis markings (compensating cyclotorsion) along with refractive and visual outcomes after toric IOL implantation. This prospective case series included eyes with visually significant cataracts and regular corneal astigmatism ranging from 1.25D to 4.0D, which received FLACS and toric IOL implantation, at The Eye Institute of West Florida, Largo, Florida, USA. Preoperative iris registration was used in conjunction with a femtosecond laser platform to create cyclotorsion corrected axis marks at the capsulotomy edge to facilitate toric IOL axial alignment. Patients were examined one, seven and thirty days after surgery to assess capsulotomy marks axis, toric IOL axis along with visual and refractive outcomes. Eighteen eyes of 13 patients aged 74.35 ± 8.65 years were included. Mean pre-op CDVA was 0.24 ± 0.16 LogMAR, while mean post-op UDVA was 0.09 ± 0.09 LogMAR. Mean pre-op corneal astigmatism was 1.85 ± 0.41 D, decreasing to 0.24 ± 0.41 D of refractive astigmatism postoperatively (p 0.05), respectively. No capsule-related or any other type of complications was noted. Iris-registered femtosecond laser-assisted anterior capsule axis markings are safe and may be considered as an alternative option to the known axis marking techniques for toric IOL axial alignment at the time of cataract surgery.

Robert J Weinstock,1 Margaret H Ainslie-Garcia,2 Nicole C Ferko,2 Rana A Qadeer,2 Leighton P Morris,3 Hang Cheng,3 Justis P Ehlers4,5 1Eye Institute of West Florida, Largo, FL, USA; 2Eversana, Burlington, ON, Canada; 3Alcon Vision LLC, Fort Worth, TX, USA; 4Tony and Leona Campane Center for Excellence in Image-Guided Surgery and Advanced Imaging Research, Cleveland Clinic, Cleveland, OH, USA; 5Vitreoretinal Service, Cole Eye Institute, Cleveland, OH, USACorrespondence: Justis P EhlersCole Eye Institute, 9500 Euclid Ave/I32, Cleveland, OH, USATel +1 216-636-0183Email ehlersj@ccf.orgPurpose: Musculoskeletal pain issues are prevalent in ophthalmic surgeons and can impact surgeon well-being and productivity. Heads-up displays (HUD) can improve upon conventional microscopes by reducing ergonomic stress. This study compared ergonomic outcomes between HUD and a conventional optical microscope in the operating room, as reported by ophthalmic surgeons in the US.Methods: An online questionnaire was distributed to a sample of surgeons who had experience operating with HUD. The questionnaire captured surgeon-specific variables, the validated Nordic Musculoskeletal Questionnaire, and custom questions to compare HUD and conventional microscope. A multivariable model was built to identify variables that were likely to predict improvement in pain-related issues.Results: Analysis was conducted on 64 surgeons (37 posterior-segment, 25 anterior-segment, and two mixed) with a mean 14.9 years of practice and 2.3 years using HUD. Most surgeons agreed or strongly agreed that HUD reduced the severity (64%) and frequency (63%) of pain and discomfort, improved posture (73%), and improved overall comfort (77%). Of respondents who experienced headaches, or pain and discomfort during operation, 12 (44%) reported their headaches improved and 45 (82%) reported feeling less pain and discomfort since they started using HUD. The multivariable model indicated the odds of reporting an improvement in pain since introducing the HUD in the operating room were 5.12-times greater for those who used HUD in > 50% of their cases (P=0.029).Conclusion: This study indicates that heads-up display may be an important tool for wellness in the operating room as it can benefit ophthalmic surgeons across several ergonomic measures.Keywords: heads-up display, microscope, ergonomic, musculoskeletal disorders, ophthalmology, surgery

To assess ocular cyclorotation of eyes having femtosecond laser-assisted cataract surgery using iris registration.Eye Institute of West Florida, Largo, Florida, USA.Retrospective cases series.Charts of patients who had femtosecond laser-assisted cataract surgery with preoperative and intraoperative iris registration in 1 or 2 eyes between November 2015 and March 2016 were reviewed. Cyclorotation was assessed via iris-registration acquired preoperatively using the Cassini topographer (patient in upright position) and intraoperatively using the iris registration option of the Lensar laser system (patient in supine position) acquired immediately before the laser treatment.The study comprised 241 patients (337 eyes). The mean age of the 107 men and 134 women was 68.0 years ± 9.0 (SD) (range 37 to 90 years). The mean absolute value of cyclorotation was 5.81 ± 4.20 degrees (range 0 to 17 degrees), which was statistically significant when comparing the preoperative axis with the intraoperative axis deviation (P .0001). Overall, incyclorotation (67.4%) was more common than excyclorotation (30.9%). In patients having bilateral femtosecond laser-assisted cataract surgery, bilateral incyclorotation (47.37%) was the most common occurrence.During femtosecond laser-assisted cataract surgery, clinically significant cyclotorsion that might influence astigmatism correction outcomes can occur in patients having cataract extraction. Iris registration was useful in accounting for cyclorotation during this procedure when corneal or intraocular lens-based forms of astigmatic corrections will be used.

Dysfunctional tear syndrome (DTS) is a common and complex condition affecting the ocular surface. The health and normal functioning of the ocular surface is dependent on a stable and sufficient tear film. Clinician awareness of conditions affecting the ocular surface has increased in recent years because of expanded research and the publication of diagnosis and treatment guidelines pertaining to disorders resulting in DTS, including the Delphi panel treatment recommendations for DTS (2006), the International Dry Eye Workshop (DEWS) (2007), the Meibomian Gland Dysfunction (MGD) Workshop (2011), and the updated Preferred Practice Pattern guidelines from the American Academy of Ophthalmology pertaining to dry eye and blepharitis (2013). Since the publication of the existing guidelines, new diagnostic techniques and treatment options that provide an opportunity for better management of patients have become available. Clinicians are now able to access a wealth of information that can help them obtain a differential diagnosis and treatment approach for patients presenting with DTS. This review provides a practical and directed approach to the diagnosis and treatment of patients with DTS, emphasizing treatment that is tailored to the specific disease subtype as well as the severity of the condition.

Background and Overview Patients with factor VII deficiency have an increased risk of prolonged perioperative hemorrhage. In this article, the authors present a case of severe factor VII deficiency in a patient who required tooth extraction. Case Description A 44-year-old woman with severe congenital factor VII deficiency sought care for a symptomatic, carious, and nonrestorable maxillary right second molar that required extraction. The authors obtained hematologic consultation, and the patient underwent the extraction under general anesthesia in the inpatient setting. Perioperative management included performing relevant laboratory studies, preoperative recombinant factor VII infusion, and postoperative intravenous aminocaproic acid administration. No hemorrhagic complications occurred throughout the perioperative course. Conclusions and Practical Implications The degree of factor VII deficiency correlates poorly with bleeding risk. Perioperative management is variable, requiring preoperative consultation with a hematologist.

Background Root canal therapy (RCT) is a commonly performed dental procedure that has a good success rate. Complications of RCT usually are minor, but severe complications can occur. Case Description A 59-year-old Hispanic man with no history of coagulopathy started to hemorrhage profusely from the mesiolingual canal of the right mandibular first molar (tooth no. 30) during RCT. The general dentist practitioner briefly controlled the hemorrhaging by packing a gutta-percha point into the mesiolingual canal. Shortly afterward, the patient developed an expanding hematoma in the submandibular space. The authors extracted tooth no. 30, raised buccal and lingual flaps, and evacuated the hematoma. Practical Implications It is possible for clinicians to encounter significant hemorrhaging and airway compromising swelling when performing root canal therapy. Clinicians must recognize and understand how to manage such complications when they occur.

Thyroid crisis, also known as thyroid storm, is a rare complication of thyrotoxicosis that results in a hypermetabolic and hyperadrenergic state. This condition requires prompt recognition and treatment because the mortality from thyroid crisis approaches 30%. Thyrotoxicosis alone will usually not progress to thyroid crisis. Thyroid crisis will typically be precipitated by some concomitant event such as infection, iodine-containing contrast agents, medications such as amiodarone, pregnancy, or surgery. Trauma is a rare precipitator of thyroid crisis. Several published studies have reported thyroid crisis resulting from blunt or penetrating neck trauma. Significant systemic trauma, such as motor vehicle accidents, has also been reported to precipitate thyroid crisis. It is very unusual for minor trauma to precipitate thyroid crisis. In the present study, we report the case of a patient who had incurred relatively minor maxillofacial trauma and developed thyroid crisis 2 weeks after the initial trauma.