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Sindhi word segmentation is a challenging task due to space omission and insertion issues. The Sindhi language itself adds to this complexity. It’s cursive and consists of characters with inherent joining and non-joining properties, independent of word boundaries. Existing Sindhi word segmentation methods rely on designing and combining hand-crafted features. However, these methods have limitations, such as difficulty handling out-of-vocabulary words, limited robustness for other languages, and inefficiency with large amounts of noisy or raw text. Neural network-based models, in contrast, can automatically capture word boundary information without requiring prior knowledge. In this paper, we propose a Subword-Guided Neural Word Segmenter (SGNWS) that addresses word segmentation as a sequence labeling task. The SGNWS model incorporates subword representation learning through a bidirectional long short-term memory encoder, position-aware self-attention, and a conditional random field. Our empirical results demonstrate that the SGNWS model achieves state-of-the-art performance in Sindhi word segmentation on six datasets.

Background: The COVID-19 pandemic remains an immediate and present concern, yet as of now there is still no approved therapeutic available for the treatment of COVID-19.This study aimed to investigate and report evidence concerning demographic characteristics and currently-used medications that contribute to the ultimate outcomes of COVID-19 ICU patients. Methods: A retrospective cohort study was conducted among all COVID-19 patients in the Intensive Care Unit (ICU) of Asir Central Hospital in Saudi Arabia between the 1st and 30th of June 2020. Data extracted from patients’ medical records included their demographics, home medications, medications used to treat COVID-19, treatment durations, ICU stay, hospital stay, and ultimate outcome (recovery or death).Descriptive statistics and regression modelling were used to analyze and compare the results. The study was approved by the Institutional Ethics Committees at both Asir Central Hospital and King Khalid University. Results: A total of 118 patients with median age of 57 years having definite clinical and disease outcomes were included in the study. Male patients accounted for 87% of the study population, and more than 65% experienced at least one comorbidity. The mean hospital and ICU stay was 11.4 and 9.8 days, respectively. The most common drugs used were tocilizumab (31.4%), triple combination therapy (45.8%), favipiravir (56.8%), dexamethasone (86.7%), and enoxaparin (83%). Treatment with enoxaparin significantly reduced the length of ICU stay (p = 0.04) and was found to be associated with mortality reduction in patients aged 50−75 (p = 0.03), whereas the triple regimen therapy and tocilizumab significantly increased the length of ICU stay in all patients (p = 0.01, p = 0.02 respectively). Conclusion: COVID-19 tends to affect males more significantly than females. The use of enoxaparin is an important part of COVID-19 treatment, especially for those above 50 years of age, while the use of triple combination therapy and tocilizumab in COVID-19 protocols should be reevaluated and restricted to patients who have high likelihood of benefit.

About half of the people who develop heart failure (HF) die within five years of diagnosis. Over the years, researchers have developed several machine learning-based models for the early prediction of HF and to help cardiologists to improve the diagnosis process. In this paper, we introduce an expert system that stacks two support vector machine (SVM) models for the effective prediction of HF. The first SVM model is linear and L1 regularized. It has the capability to eliminate irrelevant features by shrinking their coefficients to zero. The second SVM model is L2 regularized. It is used as a predictive model. To optimize the two models, we propose a hybrid grid search algorithm (HGSA) that is capable of optimizing the two models simultaneously. The effectiveness of the proposed method is evaluated using six different evaluation metrics: accuracy, sensitivity, specificity, the Matthews correlation coefficient (MCC), ROC charts, and area under the curve (AUC). The experimental results confirm that the proposed method improves the performance of a conventional SVM model by 3.3%. Moreover, the proposed method shows better performance compared to the ten previously proposed methods that achieved accuracies in the range of 57.85%-91.83%. In addition, the proposed method also shows better performance than the other state-of-the-art machine learning ensemble models.

Heart failure is considered one of the leading cause of death around the world. The diagnosis of heart failure is a challenging task especially in under-developed and developing countries where there is a paucity of human experts and equipments. Hence, different researchers have developed different intelligent systems for automated detection of heart failure. However, most of these methods are facing the problem of overfitting i.e. the recently proposed methods improved heart failure detection accuracy on testing data while compromising heart failure detection accuracy on training data. Consequently, the constructed models overfit to the testing data. In order, to come up with an intelligent system that would show good performance on both training and testing data, in this paper we develop a novel diagnostic system. The proposed diagnostic system uses random search algorithm (RSA) for features selection and random forest model for heart failure prediction. The proposed diagnostic system is optimized using grid search algorithm. Two types of experiments are performed to evaluate the precision of the proposed method. In the first experiment, only random forest model is developed while in the second experiment the proposed RSA based random forest model is developed. Experiments are performed using an online heart failure database namely Cleveland dataset. The proposed method is efficient and less complex than conventional random forest model as it produces 3.3% higher accuracy than conventional random forest model while using only 7 features. Moreover, the proposed method shows better performance than five other state of the art machine learning models. In addition, the proposed method achieved classification accuracy of 93.33% while improving the training accuracy as well. Finally, the proposed method shows better performance than eleven recently proposed methods for heart failure detection.

The population models allow for a better understanding of the dynamical interactions with the environment and hence can provide a way for understanding the population changes. They are helpful in studying the biological invasions, environmental conservation and many other applications. These models become more complicated when accounting for the stochastic and/or random variations due to different sources. In the current work, a spectral technique is suggested to analyze the stochastic population model with random parameters. The model contains mixed sources of uncertainties, noise and uncertain parameters. The suggested algorithm uses the spectral decompositions for both types of randomness. The spectral techniques have the advantages of high rates of convergence. A deterministic system is derived using the statistical properties of the random bases. The classical analytical and/or numerical techniques can be used to analyze the deterministic system and obtain the solution statistics. The technique presented in the current work is applicable to many complex systems with both stochastic and random parameters. It has the advantage of separating the contributions due to different sources of uncertainty. Hence, the sensitivity index of any uncertain parameter can be evaluated. This is a clear advantage compared with other techniques used in the literature.