Search

Your search keyword '"Rasmussen, Peter"' showing total 848 results
Start Over Author "Rasmussen, Peter" Search Limiters Peer Reviewed
848 results on '"Rasmussen, Peter"'

2. Two decades of SVT ablation in Denmark: a trend towards higher age, more comorbidity, and less prior use of antiarrhythmic and rate-limiting pharmacotherapy—a nationwide registry-based Danish study

Author

Middelfart, Charlotte, Tønnesen, Jacob, Zörner, Christopher R., Da Riis-Vestergaard, Lise, Pham, Maria Hang Xuan, Pallisgaard, Jannik Langtved, Ruwald, Martin H., Rasmussen, Peter Vibe, Johannessen, Arne, Hansen, Jim, Worck, Rene, Gislason, Gunnar, and Hansen, Morten Lock

Published
2024
Full Text
View/download PDF

6. 100 ancient genomes show repeated population turnovers in Neolithic Denmark

Author

Allentoft, Morten E., Sikora, Martin, Fischer, Anders, Sjögren, Karl-Göran, Ingason, Andrés, Macleod, Ruairidh, Rosengren, Anders, Schulz Paulsson, Bettina, Jørkov, Marie Louise Schjellerup, Novosolov, Maria, Stenderup, Jesper, Price, T. Douglas, Fischer Mortensen, Morten, Nielsen, Anne Birgitte, Ulfeldt Hede, Mikkel, Sørensen, Lasse, Nielsen, Poul Otto, Rasmussen, Peter, Jensen, Theis Zetner Trolle, Refoyo-Martínez, Alba, Irving-Pease, Evan K., Barrie, William, Pearson, Alice, Sousa da Mota, Bárbara, Demeter, Fabrice, Henriksen, Rasmus A., Vimala, Tharsika, McColl, Hugh, Vaughn, Andrew, Vinner, Lasse, Renaud, Gabriel, Stern, Aaron, Johannsen, Niels Nørkjær, Ramsøe, Abigail Daisy, Schork, Andrew Joseph, Ruter, Anthony, Gotfredsen, Anne Birgitte, Henning Nielsen, Bjarne, Brinch Petersen, Erik, Kannegaard, Esben, Hansen, Jesper, Buck Pedersen, Kristoffer, Pedersen, Lisbeth, Klassen, Lutz, Meldgaard, Morten, Johansen, Morten, Uldum, Otto Christian, Lotz, Per, Lysdahl, Per, Bangsgaard, Pernille, Petersen, Peter Vang, Maring, Rikke, Iversen, Rune, Wåhlin, Sidsel, Anker Sørensen, Søren, Andersen, Søren H., Jørgensen, Thomas, Lynnerup, Niels, Lawson, Daniel J., Rasmussen, Simon, Korneliussen, Thorfinn Sand, Kjær, Kurt H., Durbin, Richard, Nielsen, Rasmus, Delaneau, Olivier, Werge, Thomas, Kristiansen, Kristian, and Willerslev, Eske

Published
2024
Full Text
View/download PDF

7. Population genomics of post-glacial western Eurasia

Author

Allentoft, Morten E., Sikora, Martin, Refoyo-Martínez, Alba, Irving-Pease, Evan K., Fischer, Anders, Barrie, William, Ingason, Andrés, Stenderup, Jesper, Sjögren, Karl-Göran, Pearson, Alice, Sousa da Mota, Bárbara, Schulz Paulsson, Bettina, Halgren, Alma, Macleod, Ruairidh, Jørkov, Marie Louise Schjellerup, Demeter, Fabrice, Sørensen, Lasse, Nielsen, Poul Otto, Henriksen, Rasmus A., Vimala, Tharsika, McColl, Hugh, Margaryan, Ashot, Ilardo, Melissa, Vaughn, Andrew, Fischer Mortensen, Morten, Nielsen, Anne Birgitte, Ulfeldt Hede, Mikkel, Johannsen, Niels Nørkjær, Rasmussen, Peter, Vinner, Lasse, Renaud, Gabriel, Stern, Aaron, Jensen, Theis Zetner Trolle, Scorrano, Gabriele, Schroeder, Hannes, Lysdahl, Per, Ramsøe, Abigail Daisy, Skorobogatov, Andrei, Schork, Andrew Joseph, Rosengren, Anders, Ruter, Anthony, Outram, Alan, Timoshenko, Aleksey A., Buzhilova, Alexandra, Coppa, Alfredo, Zubova, Alisa, Silva, Ana Maria, Hansen, Anders J., Gromov, Andrey, Logvin, Andrey, Gotfredsen, Anne Birgitte, Henning Nielsen, Bjarne, González-Rabanal, Borja, Lalueza-Fox, Carles, McKenzie, Catriona J., Gaunitz, Charleen, Blasco, Concepción, Liesau, Corina, Martinez-Labarga, Cristina, Pozdnyakov, Dmitri V., Cuenca-Solana, David, Lordkipanidze, David O., En’shin, Dmitri, Salazar-García, Domingo C., Price, T. Douglas, Borić, Dušan, Kostyleva, Elena, Veselovskaya, Elizaveta V., Usmanova, Emma R., Cappellini, Enrico, Brinch Petersen, Erik, Kannegaard, Esben, Radina, Francesca, Eylem Yediay, Fulya, Duday, Henri, Gutiérrez-Zugasti, Igor, Merts, Ilya, Potekhina, Inna, Shevnina, Irina, Altinkaya, Isin, Guilaine, Jean, Hansen, Jesper, Aura Tortosa, Joan Emili, Zilhão, João, Vega, Jorge, Buck Pedersen, Kristoffer, Tunia, Krzysztof, Zhao, Lei, Mylnikova, Liudmila N., Larsson, Lars, Metz, Laure, Yepiskoposyan, Levon, Pedersen, Lisbeth, Sarti, Lucia, Orlando, Ludovic, Slimak, Ludovic, Klassen, Lutz, Blank, Malou, González-Morales, Manuel, Silvestrini, Mara, Vretemark, Maria, Nesterova, Marina S., Rykun, Marina, Rolfo, Mario Federico, Szmyt, Marzena, Przybyła, Marcin, Calattini, Mauro, Sablin, Mikhail, Dobisíková, Miluše, Meldgaard, Morten, Johansen, Morten, Berezina, Natalia, Card, Nick, Saveliev, Nikolai A., Poshekhonova, Olga, Rickards, Olga, Lozovskaya, Olga V., Gábor, Olivér, Uldum, Otto Christian, Aurino, Paola, Kosintsev, Pavel, Courtaud, Patrice, Ríos, Patricia, Mortensen, Peder, Lotz, Per, Persson, Per, Bangsgaard, Pernille, de Barros Damgaard, Peter, Vang Petersen, Peter, Martinez, Pilar Prieto, Włodarczak, Piotr, Smolyaninov, Roman V., Maring, Rikke, Menduiña, Roberto, Badalyan, Ruben, Iversen, Rune, Turin, Ruslan, Vasilyev, Sergey, Wåhlin, Sidsel, Borutskaya, Svetlana, Skochina, Svetlana, Sørensen, Søren Anker, Andersen, Søren H., Jørgensen, Thomas, Serikov, Yuri B., Molodin, Vyacheslav I., Smrcka, Vaclav, Merts, Victor, Appadurai, Vivek, Moiseyev, Vyacheslav, Magnusson, Yvonne, Kjær, Kurt H., Lynnerup, Niels, Lawson, Daniel J., Sudmant, Peter H., Rasmussen, Simon, Korneliussen, Thorfinn Sand, Durbin, Richard, Nielsen, Rasmus, Delaneau, Olivier, Werge, Thomas, Racimo, Fernando, Kristiansen, Kristian, and Willerslev, Eske

Published
2024
Full Text
View/download PDF

22. Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Toward Goblet Cells

Author

He, Shijie, Lei, Peng, Kang, Wenying, Cheung, Priscilla, Xu, Tao, Mana, Miyeko, Park, Chan Young, Wang, Hongyan, Imada, Shinya, Russell, Jacquelyn O., Wang, Jianxun, Wang, Ruizhi, Zhou, Ziheng, Chetal, Kashish, Stas, Eric, Mohad, Vidisha, Bruun-Rasmussen, Peter, Sadreyev, Ruslan I., Hodin, Richard A., Zhang, Yanhang, Breault, David T., Camargo, Fernando D., Yilmaz, Ömer H., Fredberg, Jeffrey J., and Saeidi, Nima

Published
2023
Full Text
View/download PDF

27. Cerebral blood flow regulation in hypobaric hypoxia: role of haemoconcentration.

Author

Turner, Rachel, Rasmussen, Peter, Gatterer, Hannes, Tremblay, Joshua C., Roche, Johanna, Strapazzon, Giacomo, Roveri, Giulia, Lawley, Justin, and Siebenmann, Christoph

Subjects
*BLOOD flow, *HYPOXEMIA, *BRAIN injuries, *HUMAN physiology, *HEMODYNAMICS
Abstract

During acute hypoxic exposure, cerebral blood flow (CBF) increases to compensate for the reduced arterial oxygen content (CaO2). Nevertheless, as exposure extends, both CaO2 and CBF progressively normalize. Haemoconcentration is the primary mechanism underlying the CaO2 restoration and may therefore explain, at least in part, the CBF normalization. Accordingly, we tested the hypothesis that reversing the haemoconcentration associated with extended hypoxic exposure returns CBF towards the values observed in acute hypoxia. Twenty‐three healthy lowlanders (12 females) completed two identical 4‐day sojourns in a hypobaric chamber, one in normoxia (NX) and one in hypobaric hypoxia (HH, 3500 m). CBF was measured by ultrasound after 1, 6, 12, 48 and 96 h and compared between sojourns to assess the time course of changes in CBF. In addition, CBF was measured at the end of the HH sojourn after hypervolaemic haemodilution. Compared with NX, CBF was increased in HH after 1 h (P = 0.001) but similar at all later time points (all P > 0.199). Haemoglobin concentration was higher in HH than NX from 12 h to 96 h (all P < 0.001). While haemodilution reduced haemoglobin concentration from 14.8 ± 1.0 to 13.9 ± 1.2 g·dl−1 (P < 0.001), it did not increase CBF (974 ± 282 to 872 ± 200 ml·min−1; P = 0.135). We thus conclude that, at least at this moderate altitude, haemoconcentration is not the primary mechanism underlying CBF normalization with acclimatization. These data ostensibly reflect the fact that CBF regulation at high altitude is a complex process that integrates physiological variables beyond CaO2. Key points: Acute hypoxia causes an increase in cerebral blood flow (CBF). However, as exposure extends, CBF progressively normalizes.We investigated whether hypoxia‐induced haemoconcentration contributes to the normalization of CBF during extended hypoxia.Following 4 days of hypobaric hypoxic exposure (corresponding to 3500 m altitude), we measured CBF before and after abolishing hypoxia‐induced haemoconcentration by hypervolaemic haemodilution.Contrary to our hypothesis, the haemodilution did not increase CBF in hypoxia.Our findings do not support haemoconcentration as a stimulus for the CBF normalization during extended hypoxia. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

28. Advancing physiology through transparency: Celebrating our first registered report.

Author

Rasmussen, Peter, Tipton, Michael J., Stewart, Alex, and Bailey, Damian M.

Subjects
*HIGH-intensity interval training, *SCHOLARSHIPS, *INTELLECTUAL property theft, *HUMAN physiology, *OPEN scholarship
Abstract

The article emphasizes the importance of transparency in scientific research, specifically focusing on the benefits of preregistration and registered reporting to enhance credibility and reproducibility. It discusses the value of separating hypothesis-testing and hypothesis-generating analyses, as well as the role of interdisciplinary collaborations in study design. The study also addresses common misconceptions about registered reports, highlighting their applicability across various disciplines and their contribution to improving research quality and credibility, particularly in the biomedical field. [Extracted from the article]

Published
2024
Full Text
View/download PDF

30. Prognostic factors for disease activity in newly diagnosed teriflunomide-treated patients with multiple sclerosis: a nationwide Danish study.

Author

Mahler, Mie Reith, Magyari, Melinda, Pontieri, Luigi, Elberling, Frederik, Holm, Rolf Pringler, Weglewski, Arkadiusz, Poulsen, Mai Bang, Storr, Lars Kristian, Bekyarov, Plamen Anzhelov, Illes, Zsolt, Kant, Matthias, Sejbaek, Tobias, Stilund, Morten Leif, Rasmussen, Peter V., Brask, Maria, Urbonaviciute, Inga, and Sellebjerg, Finn

Subjects
MEDICAL sciences, SEX factors in disease, GENERAL Data Protection Regulation, 2016, PROPORTIONAL hazards models, PATIENT selection
Published
2024
Full Text
View/download PDF

31. Telecoaching of Individuals With Multiple Sclerosis After Inpatient Multidisciplinary Rehabilitation: The Danish MS Hospitals Rehabilitation Study.

Author

Nørgaard, Michael, Boesen, Finn, Guldhammer Skjerbæk, Anders, Jensen, Ellen, Hansen, Jeanne, Vestergaard Rasmussen, Peter, Petersen, Thor, and Trénel, Philipp

Abstract

BACKGROUND: Inpatient rehabi l i tation improves health-related quality of life (HRQOL) for people with multiple sclerosis (MS). However, the obtained improvements decline once people return home. The challenge is to find ways to preserve the beneficial effects for the long term. We investigated whether monthly telecoaching after discharge would enhance the long-term carryover of improvements. METHODS: We conducted a 1-year exploratory study with 2 delivery methods: telephone coaching and web-based coaching. After discharge, the telephone group received monthly calls; the web-based group responded to monthly online coaching questions. Based on their rehabilitation goals, we put patients into a neuropsychological group or a physical group. In addition, we matched each patient with similar wait-list control patients and treatment patients from the main study. The primary outcome was HRQOL measured by the Functional Assessment in Multiple Sclerosis (FAMS). RESULTS: The neuropsychological group had long-term preservation of HRQOL with both delivery methods, with telephone coaching seeming to be superior. Mean differences in FAMS at the 12-month median follow-up for the neuropsychological group compared with the control wait-list control group were for the telephone group: + 15.4 (95% CI, 3.5-27.4; P = .011); for the web-based group: + 10.9 (95% CI, -3.3 to 25.2; P = .130); for the control treatment group: + 6.9 (95% CI, 0.6-13.3; P = .031). The physical group saw no beneficial effects from telecoaching. CONCLUSIONS: Following inpatient multidisciplinary rehabilitation, monthly telecoaching of individuals with MS with neuropsychological challenges enhanced the long-term carryover of HRQOL, with one-on-one telephone coaching showing more pronounced improvements than web-based automated coaching. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

32. Shedding Light on the Black Box of Rehabilitation: Differential Short- and Long-Term Effects of Multidisciplinary Multiple Sclerosis Rehabilitation.

Author

Trénel, Philipp, Boesen, Finn, Guldhammer Skjerbæk, Anders, Petersen, Thor, Vestergaard Rasmussen, Peter, and Nørgaard, Michael

Abstract

BACKGROUND: The study of the effectiveness of multidisciplinary rehabilitation (MDR) and how the symptoms and needs of individuals with multiple sclerosis (MS) interplay with the diversity of MDR interventions is still a conundrum, often referred to as a black box. METHODS: We conducted a partial crossover randomized controlled trial with follow-ups at 1 (discharge), 6, and 12 months. Based on their rehabilitation goals, each patient was categorized into 1 of 5 main focus areas (MFAs) prior to admission: Resilience, Cognitive Function, Energy, Physical Function, and Personal Needs. The Functional Assessment of Multiple Sclerosis (FAMS) instrument scores were the primary outcome. RESULTS: MFA groups varied in age (P = .036), MS type (P = .002), Expanded Disability Status Scale score (P < .001), time since diagnosis (P = .002), and FAMS at baseline (P < .001), as well as in composition and quantity of MDR services. At discharge, significant FAMS improvements were found in all 5 MFA groups (FAMS change > 10.4, P < .05), but the affected subdimensions and persistence of improvements varied among MFA groups. At the 6-month follow-up, estimates of controlled differences in FAMS were 9.9 (P =.001), 5.6 (P = .196), 8.5 (P = .008), -1.4 (P = .548), and 17.9 (P = .012) for the Resilience, Cognitive Function, Energy, Physical Function, and Personal Needs groups, respectively. CONCLUSIONS: This study demonstrated that inpatient MDR improves functioning and health-related quality of life in people with MS; the type, degree, and persistence of the benefits are associated with a patient's main focus area of rehabilitation, which signifies the importance of the goal-setting process in MDR. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

33. Disparities in the access to atrial fibrillation ablation in Denmark: who gets ablated, who neglected?

Author

Zörner, Christopher R, Tønnesen, Jacob, Riis-Vestergaard, Lise Da, Middelfart, Charlotte, Hein, Regitze, Rasmussen, Peter Vibe, Ruwald, Martin H, Gislason, Gunnar, and Hansen, Morten Lock

Abstract

Aims Atrial fibrillation (AF) is a common arrhythmia associated with reduced quality of life that can lead to serious complications such as stroke and heart failure. Ablation is a safe and effective treatment for AF but is not offered equally to all patients. The aim of this study is to identify demographic groups more or less likely to undergo AF ablation. Methods and results All patients with newly diagnosed AF between 2010 and 2018 were identified in the Danish nationwide registries. The association between gender, age, level of education and attachment to the job market, and the likelihood of receiving AF ablation was investigated using multivariable Cox proportional hazard analysis. Cumulative incidence was calculated using the Aalen–Johansen estimator. A total of 176 248 patients were included. Men were more likely to receive ablation than women (7% vs. 3%). Patients aged 25–44 and 45–64 were most likely to receive ablation, while only 0.7% of patients aged 80 or above received ablation. The rate of ablation significantly decreased with decreasing level of education. Full-time employed patients were most likely to receive ablation, followed by self-employed, unemployed, on sick leave, undergoing education, and early retired patients. Retired patients were the least likely to receive ablation (3%). Conclusion This study found that women, older patients, patients with lower levels of education, and patients on social benefits are less likely to receive AF ablation. These findings suggest that there are significant social and economic disparities in AF ablation treatment in Denmark. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

42. Understanding the incidence of atrial fibrillation and stroke in hypertrophic cardiomyopathy patients: insights from Danish nationwide registries.

Author

Zörner, Christopher R, Schjerning, Anne-Marie, Jensen, Morten Kvistholm, Christensen, Alex Hørby, Tfelt-Hansen, Jacob, Tønnesen, Jacob, Riis-Vestergaard, Lise Da, Middelfart, Charlotte, Rasmussen, Peter Vibe, Gislason, Gunnar, and Hansen, Morten Lock

Abstract

Aims The treatment of atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM) can be challenging since AF aggravates symptoms and increases the risk of stroke. Which factors contribute to the development of AF and stroke in HCM remains unknown. The aim of this study was to determine the incidence of AF and stroke in HCM patients and identify the risk factors. Methods and results Using Danish national registries, all HCM patients from 2005 to 2018 were included. The association between HCM, incident AF, and stroke was investigated using multivariable Cox proportional hazards analysis. Cumulative incidences were calculated using the Aalen–Johansen estimator. Among the 3367 patients without prevalent AF, 24% reached the endpoint of incident AF with death as a competing risk. Median follow-up time was 4 years. Atrial fibrillation incidence was equal between sexes and increased for patients with ischaemic heart disease [IHD; hazard ratio (HR) 1.33, 95% confidence interval (CI) 1.08–1.63], hypertension (HT) (HR 1.36, 95% CI 1.14–1.67), and obstructive HCM (HR 1.27, 95% CI 1.05–1.52). Seven per cent developed stroke, with no difference detected stratifying for the presence of AF. Sub-analysis revealed that when AF was treated with oral anticoagulants (OACs), stroke was less likely (HR 0.4, 95% CI 0.18–0.86, P = 0.02). However, 34% of patients were not receiving adequate anticoagulation following AF diagnosis. Conclusion Obstructive HCM, HT, and IHD were associated with increased risk of AF. Prevalent AF alone was not predictive of stroke; however, AF patients treated with OAC were significantly less likely to develop stroke, suggesting that this development is driven by the protective effect of OAC. Despite this, 34% of patients did not receive OAC. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

43. Effect of early cryoballoon ablation on atrial fibrillation recurrence—A Danish nationwide register study.

Author

Hein, Regitze, Riis‐Vestergaard, Lise Da, Tønnesen, Jacob, Zörner, Christopher Ryan, Rasmussen, Peter Vibe, Ruwald, Martin Huth, Johannessen, Arne, Worck, René Husted, Hansen, Jim, Middelfart, Charlotte, Gislason, Gunnar Hilmar, and Hansen, Morten Lock

Subjects
RISK assessment, RESEARCH funding, CLINICAL trials, CRYOSURGERY, TREATMENT effectiveness, PATIENT care, LONGITUDINAL method, ATRIAL fibrillation, DISEASE relapse, CONFIDENCE intervals, TIME, PROPORTIONAL hazards models, REGRESSION analysis
Abstract

Introduction: Cryoballoon ablation is a safe and efficient rhythm control strategy in atrial fibrillation (AF) patients. The impact of time from diagnosis to ablation is unclear. The aim of this study was to examine the impact of timing of first‐time cryoballoon ablation on AF recurrence in a nationwide cohort of AF patients. Methods and Results: From nationwide registers, all AF patients ≥18 years of age who underwent first‐time AF cryoballoon ablation in Denmark from 2012 to 2018 were included. The AF patients were stratified by ablation timing: Early group (≤1 year after AF diagnosis), intermediate group (1–3 years after AF diagnosis), and late group (≥3 years after AF diagnosis). By adjusted Cox regression models, the effect of timing on AF recurrence was examined. This study included 1064 AF patients with a median age of 63 years. Most patients were male (66%) and had paroxysmal AF (67%). The 1‐year risk of AF recurrence increased from 31% in the early group to 41% and 44% in the intermediate and late group. The hazard ratios (95% confidence intervals) were 1.28 (0.95, 1.74) in the intermediate group and 1.42 (1.09, 1.86) in the late group when compared to the early group. Continuous diagnosis‐to‐ablation time seemed to have the greatest impact on AF recurrence within the first 2 years. Conclusion: In AF patients undergoing cryoballoon ablation, late timing of ablation was associated with a significantly higher AF recurrence rate when compared to early timing of ablation. These findings support early cryoballoon ablation to improve the outcomes after ablation. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

44. Use of virtual visits for the care of the arrhythmia patient

Author

Hu, Peter T, Hilow, Henry, Patel, Divyang, Eppich, Megan, Cantillon, Daniel, Tchou, Patrick, Bhargava, Mandeep, Kanj, Mohamed, Baranowski, Bryan, Hussein, Ayman, Callahan, Thomas, Saliba, Walid, Dresing, Thomas, Wilkoff, Bruce L., Rasmussen, Peter A., Wazni, Oussama, and Tarakji, Khaldoun G.

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results