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Long-term variability of the mesosphere/lower thermosphere (lower E region ionosphere) since 1970 has been analyzed using wind data series obtained at Collm (52° N, 15° E) using the LF drift method and at Obninsk (55° N, 37° E) applying VHF meteor radar. Applying piecewise linear trend analysis with a priori unknown number and positions of breakpoints shows that trend models with breakpoints are generally to be preferred against straight lines. There is a strong indication for a change of trends in wind parameters around 1975–1980. Similar changes are also found in the lower atmosphere, e.g., in tropospheric temperatures. This indicates a coupling between atmospheric layers at time scales of decades.