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16. The EQ-HWB: Overview of the Development of a Measure of Health and Wellbeing and Key Results

Author

Brazier, John, Peasgood, Tessa, Mukuria, Clara, Marten, Ole, Kreimeier, Simone, Luo, Nan, Mulhern, Brendan, Pickard, A. Simon, Augustovski, Federico, Greiner, Wolfgang, Engel, Lidia, Belizan, Maria, Yang, Zhihao, Monteiro, Andrea, Kuharic, Maja, Gibbons, Luz, Ludwig, Kristina, Carlton, Jill, Connell, Janice, Rand, Stacey, Devlin, Nancy, Jones, Karen, Tsuchiya, Aki, Lovett, Rosemary, Naidoo, Bhash, Rowen, Donna, and Rejon-Parrilla, Juan Carlos

Published
2022
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23. The Functional Assessment of Cancer Therapy Eight Dimension (FACT-8D), a Multi-Attribute Utility Instrument Derived From the Cancer-Specific FACT-General (FACT-G) Quality of Life Questionnaire: Development and Australian Value Set

Author

Aaronson, N., Brazier, J., Cella, D., Costa, D.S.J., Fayers, P., Grimison, P., Janda, M., Kemmler, G., King, M.T., McTaggart-Cowan, H., Mercieca-Bebber, R., Norman, R., Peacock, S., Pickard, A.S., Rowen, D., Velikova, G., Viney, R., Street, D., Young, T., King, Madeleine T., Norman, Richard, Mercieca-Bebber, Rebecca, Costa, Daniel S.J., McTaggart-Cowan, Helen, Peacock, Stuart, Janda, Monika, Müller, Fabiola, Viney, Rosalie, Pickard, Alan Simon, and Cella, David

Published
2021
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29. Implementation of virtual academic detailing in North America: A qualitative study.

Author

Nazari, Jonathan L., Kulbokas, Victoria, Smart, Mary H., Hensle, Tara R., Lee, Todd A., and Pickard, A. Simon

Subjects
SUBSTANCE abuse, QUALITATIVE research, RESEARCH funding, INTERVIEWING, EDUCATIONAL technology, MOTIVATION (Psychology), ATTITUDES of medical personnel, ONLINE education, RESEARCH methodology, CONCEPTUAL structures, PROFESSIONAL employee training, OPIOID epidemic, CONTINUING education, HEALTH equity, COVID-19 pandemic
Abstract

Rationale: The shift toward virtual academic detailing (AD) was accelerated by the COVID‐19 pandemic. Aims and Objectives: We aimed to examine the role of external, contextual, and intrinsic programme‐specific factors in virtual engagement of healthcare providers (HCPs) and delivery of AD. Methods: AD groups throughout North America were contacted to participate in semistructured interviews. An interview guide was constructed by adapting the Consolidated Framework for Implementation Research (CFIR). A point of emphasis included strategies AD groups employed for provider engagement while implementing virtual AD programmes. Independent coders conducted qualitative analysis using the framework method. Results: Fifteen AD groups from Canada (n = 3) and the United States (n = 12) participated. Technological issues and training detailers and HCPs were challenges during the transition to virtual AD visits. Restrictions on in‐person activities during the pandemic created difficulties engaging HCPs and fewer AD visits. Continuing education was one strategy to incentivize participation, but credits were often not claimed by HCPs. Groups with established networks and prior experience with virtual AD leveraged connections to mitigate disruptions and continue AD visits. Other facilitators included emphasizing contemporary topics, including opioid education beyond fundamental guidelines. Virtual AD had the additional benefit of expanding geographic reach and flexible scheduling with providers. Conclusions: AD groups across North America have shifted to virtual outreach and delivery strategies. This trend toward virtual AD may aid outreach to vulnerable rural communities, improving health equity. More research is needed on the effectiveness of virtual AD and its future implications. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Design of the patient navigator to Reduce Readmissions (PArTNER) study: A pragmatic clinical effectiveness trial

Author

Prieto-Centurion, Valentin, Basu, Sanjib, Bracken, Nina, Calhoun, Elizabeth, Dickens, Carolyn, DiDomenico, Robert J., Gallardo, Richard, Gordeuk, Victor, Gutierrez-Kapheim, Melissa, Hsu, Lewis L., Illendula, Sai, Joo, Min, Kazmi, Uzma, Mutso, Amelia, Pickard, A. Simon, Pittendrigh, Barry, Sullivan, Jamie L., Williams, Mark, and Krishnan, Jerry A.

Published
2019
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43. Cost‐Effectiveness of Carbidopa‐Levodopa Enteral Suspension for Advanced Parkinson's Disease in the United States.

Author

Pahwa, Rajesh, Merola, Aristide, Soileau, Michael, Alobaidi, Ali, Pickard, A. Simon, Kandukuri, Prasanna L., Bao, Yanjun, Strezewski, John, Oddsdottir, Julia, Xu, Weiwei, and Standaert, David

Abstract

Background: Carbidopa/levodopa enteral suspension (CLES) is indicated for the treatment of advanced Parkinson's disease (aPD) with severe motor fluctuations. Objective: To determine the cost, quality‐adjusted life years (QALY), and cost‐effectiveness of CLES compared to the standard‐of‐care (SoC) for aPD patients in the United States (US), using real‐world data. Methods: A published Markov model, comprising of 25 health states and a death state, (defined by a combination of the Hoehn and Yahr scale and waking time spent in OFF‐time) was adapted to estimate the benefits for CLES versus oral SoC over a patient's lifetime in the US healthcare setting. Clinical inputs were based on a clinical trial and a registry study; utility inputs were sourced from the Adelphi‐Disease Specific Programmes. Results: CLES compared to SoC was associated with incremental costs ($1,031,791 vs. $1,025,180) and QALY gain (4.61 vs. 3.76), resulting in an incremental cost‐effectiveness ratio of $7711/QALY. Conclusion: CLES is a cost‐effective treatment for aPD patients with medication resistant motor fluctuations. © 2023 AbbVie, Inc and The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society. [ABSTRACT FROM AUTHOR]

Published
2023
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49. Nonmyeloablative Stem Cell Transplantation with Alemtuzumab/Low-Dose Irradiation to Cure and Improve the Quality of Life of Adults with Sickle Cell Disease

Author

Saraf, Santosh L., Oh, Annie L., Patel, Pritesh R., Jalundhwala, Yash, Sweiss, Karen, Koshy, Matthew, Campbell-Lee, Sally, Gowhari, Michel, Hassan, Johara, Peace, David, Quigley, John G., Khan, Irum, Molokie, Robert E., Hsu, Lewis L., Mahmud, Nadim, Levinson, Dennis J., Pickard, A. Simon, Garcia, Joe G.N., Gordeuk, Victor R., and Rondelli, Damiano

Published
2016
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50. Contextual factors affecting the implementation of drug checking for harm reduction: a scoping literature review from a North American perspective.

Author

Grace Rose, Chloe, Kulbokas, Victoria, Carkovic, Emir, Lee, Todd A., and Pickard, A. Simon

Abstract

Background: The opioid epidemic continues to be a significant cause of morbidity and mortality in the US. In 2020, 83% of opioid-related overdose deaths were due to synthetic opioids, such as fentanyl. Drug checking services have been widely implemented as a harm reduction intervention to facilitate the identification of substances in a drug sample. There is a need to inform decision-making on drug checking technologies and service implementation. This research aims to outline contextual considerations for the implementation of a drug checking service. Methods: A scoping review was conducted using a structured search strategy in PubMed and EMBASE. Articles were independently screened by two reviewers, and included if they were primary literature and reported on an actionable consideration(s) for drug checking services. Data elements were extracted using a standardized form, and included study design, study population, drug checking technology utilized or discussed, and main findings. Results: Twenty-nine articles were selected for inclusion, and four primary areas of consideration were identified: drug checking technologies, venue of a drug checking service, legality, and privacy. Technological considerations include the need for highly accurate, quantitative results which appeal to both populations of people with drug use disorder and recreational users. Accessibility of services was identified as an important factor that may be impacted by the location, integration with other services, how the service is provided (mobile vs. fixed), and the hours of operation. Maintaining plausible deniability and building trust were seen as important facilitators to service use and engagement. Issues surrounding legality were the most frequently cited barrier by patrons, including fear of criminalization, policing, and surveillance. Patrons and stakeholders identified a need for supportive policies that offer protections. Maintaining anonymity for patrons is crucial to addressing privacy-related barriers. Conclusion: This review highlights the need to understand the local population and climate for drug checking to implement a drug checking service successfully. Common themes identified in the literature included considerations related to the choice of technology, the type of venue, and the impact of legality and privacy. We intend to utilize these considerations in future research to help guide discussions with US-based stakeholders. [ABSTRACT FROM AUTHOR]

Published
2023
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