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Your search keyword '"Peixoto, Eduardo M."' showing total 6 results
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6 results on '"Peixoto, Eduardo M."'

1. SARS-CoV-2 transmission in a highly vulnerable population of Brazil: a household cohort study

Author

Coelho, Lara E., Luz, Paula M., Pires, Débora C., Jalil, Emilia M., Perazzo, Hugo, Torres, Thiago S., Cardoso, Sandra W., Peixoto, Eduardo M., Nazer, Sandro, Massad, Eduardo, Carvalho, Luiz Max, Réquia, Weeberb J., Motta, Fernando Couto, Siqueira, Marilda Mendonça, Vasconcelos, Ana T.R., da Fonseca, Guilherme C., Cavalcante, Liliane T.F., Costa, Carlos A.M., Amancio, Rodrigo T., Villela, Daniel A.M., Pereira, Tiago, Goedert, Guilherme T., Santos, Cleber V.B.D., Rodrigues, Nadia C.P., Bormann de Souza Filho, Breno Augusto, Csillag, Daniel, Grinsztejn, Beatriz, Veloso, Valdilea G., and Struchiner, Claudio J.

Published
2024
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2. Mpox severity and associated hospitalizations among people with HIV and related immunosuppression in Brazil

Author

Silva, Mayara S.T., Coutinho, Carolina, Torres, Thiago S., Peixoto, Eduardo M., Bastos, Matheus O., Mesquita, Maira B., Tavares, Isabel C.F., Andrade, Hugo B., Reges, Paula P.S., Martins, Pedro S., Echeverría-Guevara, Amanda, Moreira, Ronaldo I., Lessa, Flavia Cristina S., Hoagland, Brenda, Nunes, Estevão P., Cardoso, Sandra W., Veloso, Valdilea G., and Grinsztejn, Beatriz

Published
2024
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3. Prevalence and predictors of anti-SARS-CoV-2 serology in a highly vulnerable population of Rio de Janeiro: A population-based serosurvey

Author

Coelho, Lara E., Luz, Paula M., Pires, Débora C., Jalil, Emilia M., Perazzo, Hugo, Torres, Thiago S., Cardoso, Sandra W., Peixoto, Eduardo M., Nazer, Sandro, Massad, Eduardo, Silveira, Mariângela F., Barros, Fernando C., Vasconcelos, Ana T.R., Costa, Carlos A.M., Amancio, Rodrigo T., Villela, Daniel A.M., Pereira, Tiago, Goedert, Guilherme T., Santos, Cleber V.B.D., Rodrigues, Nadia C.P., Grinsztejn, Beatriz, Veloso, Valdilea G., and Struchiner, Claudio J.

Published
2022
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4. Mpox, sexually transmitted infections and combination prevention: insights from a major cohort in Rio de Janeiro, Brazil.

Author

Silva, Mayara S. T., Torres, Thiago S., Coutinho, Carolina, Jalil, Emilia M., Yanavich, Carolyn, Martins, Pedro S., Bastos, Matheus O., Mesquita, Maira B., Echeverría-Guevara, Amanda, Nazer, Sandro, Peixoto, Eduardo M., Terra, Marcela, Lovetro, Ana, Reges, Paula P. S., Meneguetti, Maria Roberta, Moreira, Ronaldo I., Lessa, Flavia C. S., Hoagland, Brenda, Nunes, Estevão P., and Cardoso, Sandra Wagner

Published
2024
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5. Differential Type-I Interferon Response in Buffy Coat Transcriptome of Individuals Infected with SARS-CoV-2 Gamma and Delta Variants.

Author

da Fonseca, Guilherme C., Cavalcante, Liliane T. F., Brustolini, Otávio J., Luz, Paula M., Pires, Debora C., Jalil, Emilia M., Peixoto, Eduardo M., Grinsztejn, Beatriz, Veloso, Valdilea G., Nazer, Sandro, Costa, Carlos A. M., Villela, Daniel A. M., Goedert, Guilherme T., Santos, Cleber V. B. D., Rodrigues, Nadia C. P., do Couto Motta, Fernando, Siqueira, Marilda Mendonça, Coelho, Lara E., Struchiner, Claudio J., and Vasconcelos, Ana Tereza R.

Subjects
SARS-CoV-2 Delta variant, TYPE I interferons, SARS-CoV-2, TRANSCRIPTOMES, CORONAVIRUSES, COAT proteins (Viruses), IMMUNE system
Abstract

The innate immune system is the first line of defense against pathogens such as the acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The type I-interferon (IFN) response activation during the initial steps of infection is essential to prevent viral replication and tissue damage. SARS-CoV and SARS-CoV-2 can inhibit this activation, and individuals with a dysregulated IFN-I response are more likely to develop severe disease. Several mutations in different variants of SARS-CoV-2 have shown the potential to interfere with the immune system. Here, we evaluated the buffy coat transcriptome of individuals infected with Gamma or Delta variants of SARS-CoV-2. The Delta transcriptome presents more genes enriched in the innate immune response and Gamma in the adaptive immune response. Interactome and enriched promoter analysis showed that Delta could activate the INF-I response more effectively than Gamma. Two mutations in the N protein and one in the nsp6 protein found exclusively in Gamma have already been described as inhibitors of the interferon response pathway. This indicates that the Gamma variant evolved to evade the IFN-I response. Accordingly, in this work, we showed one of the mechanisms that variants of SARS-CoV-2 can use to avoid or interfere with the host Immune system. [ABSTRACT FROM AUTHOR]

Published
2023
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6. Diaphragm quantitative electromyography in difficult-to-treat asthmatic patients.

Author

CAETANO, Marcelo R., MARANHÃO, Analucia A., PEIXOTO, Eduardo M., ALAMY, Alexandre H., CASSETA, Ana Paula, and RODRIGUES FILHO, Julio C.

Abstract

Copyright of Arquivos de Neuro-Psiquiatria is the property of Thieme Medical Publishing Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019
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