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Your search keyword '"Pérez Olaso, Oscar"' showing total 4 results
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1. Lifting COVID-19 mitigation measures in Spain (May–June 2020)

Author

Monge, Susana, Latasa Zamalloa, Pello, Sierra Moros, María José, Pérez Olaso, Oscar, García San Miguel, Lucía, Varela, Carmen, Rivera Ariza, Silvia, Vázquez Torres, María C., Olmedo Lucerón, María del Carmen, González Yuste, Paloma, Soler Crespo, Pilar, Segura del Pozo, Javier, Gullón, Pedro, Carrasco, José Miguel, Martínez Sánchez, Elena Vanessa, Redondo Bravo, Lidia, Pichiule Castañeda, Myriam, Purriños Hermida, María Jesús, Hervada Vidal, Xurxo, Huerta Gonzalez, Ismael, Margolles, Mario, Vanaclocha Luna, Hermelinda, Ramalle Gómara, Enrique, Pérez Martín, Jaime Jesús, Chirlaque López, María Dolores, López Fernández, María Jesús, Lorusso, Nicola, Carmona Ubago, Alberto, Rivas Perez, Ana, Ramos Marin, Violeta, Criado Alvarez, Juan José, Castrillejo Pérez, Daniel, Góméz Anés, Atanasio A., Frontera, Marga, Macias Rodriguez, Pedro, Álvarez León, Eva Elisa, Díaz Casañas, Miriam, Lopaz Perez, Maria Angeles, Alonso Pérez de Ágreda, Juan Pablo, Navas Gutierrez, Paloma, Rosell Aguilar, Ignacio, Arteagoitia Axpe, Jose María, Gonzalez Carril, Fernando, Aparicio Azcárraga, Pilar, Simón Soria, Fernando, and Suarez Rodríguez, Berta

Published
2023
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4. Cellular Immunity of SARS-CoV-2 in the Borriana COVID-19 Cohort: A Nested Case–Control Study.

Author

Domènech-Montoliu, Salvador, Puig-Barberà, Joan, Pac-Sa, María Rosario, Orrico-Sanchéz, Alejandro, Gómez-Lanas, Lorna, Sala-Trull, Diego, Domènech-Leon, Carmen, Del Rio-González, Alba, Sánchez-Urbano, Manuel, Satorres-Martinez, Paloma, Aparisi-Esteve, Laura, Badenes-Marques, Gema, Blasco-Gari, Roser, Casanova-Suarez, Juan, Gil-Fortuño, María, Hernández-Pérez, Noelia, Jovani-Sales, David, López-Diago, Laura, Notari-Rodríguez, Cristina, and Pérez-Olaso, Oscar

Subjects
CELLULAR immunity, SARS-CoV-2, BLOOD groups, COVID-19, COVID-19 vaccines, BLOOD group antigens, ABO blood group system
Abstract

Our goal was to determine the cellular immune response (CIR) in a sample of the Borriana COVID-19 cohort (Spain) to identify associated factors and their relationship with infection, reinfection and sequelae. We conducted a nested case–control study using a randomly selected sample of 225 individuals aged 18 and older, including 36 individuals naïve to the SARS-CoV-2 infection and 189 infected patients. We employed flow-cytometry–based immunoassays for intracellular cytokine staining, using Wuhan and BA.2 antigens, and chemiluminescence microparticle immunoassay to detect SARS-CoV-2 antibodies. Logistic regression models were applied. A total of 215 (95.6%) participants exhibited T-cell response (TCR) to at least one antigen. Positive responses of CD4+ and CD8+ T cells were 89.8% and 85.3%, respectively. No difference in CIR was found between naïve and infected patients. Patients who experienced sequelae exhibited a higher CIR than those without. A positive correlation was observed between TCR and anti-spike IgG levels. Factors positively associated with the TCR included blood group A, number of SARS-CoV-2 vaccine doses received, and anti-N IgM; factors inversely related were the time elapsed since the last vaccine dose or infection, and blood group B. These findings contribute valuable insights into the nuanced immune landscape shaped by SARS-CoV-2 infection and vaccination. [ABSTRACT FROM AUTHOR]

Published
2024
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