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9 results on '"Pala, Giovanni"'

1. Randomized Evidence for Reduction of Perioperative Mortality: An Updated Consensus Process

Author

Landoni, Giovanni, Pisano, Antonio, Lomivorotov, Vladimir, Alvaro, Gabriele, Hajjar, Ludhmila, Paternoster, Gianluca, Nigro Neto, Caetano, Latronico, Nicola, Fominskiy, Evgeny, Pasin, Laura, Finco, Gabriele, Lobreglio, Rosetta, Azzolini, Maria Luisa, Buscaglia, Giuseppe, Castella, Alberto, Comis, Marco, Conte, Adele, Conte, Massimiliano, Corradi, Francesco, Dal Checco, Erika, De Vuono, Giovanni, Ganzaroli, Marco, Garofalo, Eugenio, Gazivoda, Gordana, Lembo, Rosalba, Marianello, Daniele, Baiardo Redaelli, Martina, Monaco, Fabrizio, Tarzia, Valentina, Mucchetti, Marta, Belletti, Alessandro, Mura, Paolo, Musu, Mario, Pala, Giovanni, Paltenghi, Massimiliano, Pasyuga, Vadim, Piras, Desiderio, Riefolo, Claudio, Roasio, Agostino, Ruggeri, Laura, Santini, Francesco, Székely, Andrea, Verniero, Luigi, Vezzani, Antonella, Zangrillo, Alberto, and Bellomo, Rinaldo

Published
2017
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2. Whole-Genome Sequencing of Two Canine Herpesvirus 1 (CaHV-1) Isolates and Clinicopathological Outcomes of Infection in French Bulldog Puppies.

Author

Rocchigiani, Angela Maria, Bertoldi, Loris, Coradduzza, Elisabetta, Lostia, Giada, Pintus, Davide, Scivoli, Rosario, Cancedda, Maria Giovanna, Fiori, Mariangela Stefania, Bechere, Roberto, Murtino, Anna Pina, Pala, Giovanni, Cardeti, Giusy, Macioccu, Simona, Dettori, Maria Antonietta, Pintore, Antonio, Ligios, Ciriaco, and Puggioni, Giantonella

Subjects
WHOLE genome sequencing, BULLDOG, PUPPIES, CLINICAL pathology, NEONATAL death, NUCLEOTIDE sequencing
Abstract

Canine herpesvirus 1 (CaHV-1) infects dogs, causing neonatal death and ocular, neurological, respiratory, and reproductive problems in adults. Although CaHV-1 is widespread in canine populations, only four studies have focused on the CaHV-1 whole genome. In such context, two CaHV-1 strains from both the kidney and spleen of 20-day-old deceased French Bulldog puppies were recently isolated in Sardinia, Italy. The extracted viral DNA underwent whole-genome sequencing using the Illumina MiSeq platform. The Italian CaHV-1 genomes were nearly identical (>99%), shared the same tree branch, and clustered near the ELAL-1 (MW353125) and BTU-1 (KX828242) strains, enlarging the completely separated clade discussed by Lewin et al., in 2020. This study aims to provide new insights on the evolution of the CaHV-1, based on high-resolution whole-genome phylogenetic analysis, and on its clinicopathological characterization during a fatal outbreak in puppies. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Worldwide Opinion on Multicenter Randomized Interventions Showing Mortality Reduction in Critically Ill Patients: A Democracy-Based Medicine Approach

Author

Pisano, Antonio, Landoni, Giovanni, Lomivorotov, Vladimir, Comis, Marco, Gazivoda, Gordana, Conte, Massimiliano, Hajjar, Ludhmila, Finco, Gabriele, Jovic, Miomir, Mucchetti, Marta, Kunstýř, Jan, Paternoster, Gianluca, Likhvantsev, Valery, Ruggeri, Laura, Ma, Jun, Alvaro, Gabriele, Bukamal, Nazar, Borghi, Giovanni, Pasyuga, Vadim, Cabrini, Luca, Greco, Massimiliano, Guarracino, Fabio, Lembo, Rosalba, Lobreglio, Rosetta, Monaco, Fabrizio, Montisci, Andrea, Pala, Giovanni, Pasin, Laura, Pieri, Marina, Santini, Francesco, Silvetti, Simona, Zambon, Massimo, Baiardo Redaelli, Martina, Castella, Alberto, De Vuono, Giovanni, Lucchetta, Luca, Zangrillo, Alberto, and Bellomo, Rinaldo

Published
2016
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4. Reducing Mortality in Acute Kidney Injury Patients: Systematic Review and International Web-Based Survey

Author

Landoni, Giovanni, Bove, Tiziana, Székely, Andrea, Comis, Marco, Rodseth, Reitze N., Pasero, Daniela, Ponschab, Martin, Mucchetti, Marta, Azzolini, Maria L., Caramelli, Fabio, Paternoster, Gianluca, Pala, Giovanni, Cabrini, Luca, Amitrano, Daniele, Borghi, Giovanni, Capasso, Antonella, Cariello, Claudia, Carpanese, Anna, Feltracco, Paolo, Gottin, Leonardo, Lobreglio, Rosetta, Mattioli, Lorenzo, Monaco, Fabrizio, Morgese, Francesco, Musu, Mario, Pasin, Laura, Pisano, Antonio, Roasio, Agostino, Russo, Gianluca, Slaviero, Giorgio, Villari, Nicola, Vittorio, Annalisa, Zucchetti, Mariachiara, Guarracino, Fabio, Morelli, Andrea, De Santis, Vincenzo, Del Sarto, Paolo A., Corcione, Antonio, Ranieri, Marco, Finco, Gabriele, Zangrillo, Alberto, and Bellomo, Rinaldo

Published
2013
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5. Randomized Evidence for Reduction of Perioperative Mortality

Author

Landoni, Giovanni, Rodseth, Reitze N., Santini, Francesco, Ponschab, Martin, Ruggeri, Laura, Székely, Andrea, Pasero, Daniela, Augoustides, John G., Del Sarto, Paolo A., Krzych, Lukasz J., Corcione, Antonio, Slullitel, Alexandre, Cabrini, Luca, Le Manach, Yannick, Almeida, Rui M.S., Bignami, Elena, Biondi-Zoccai, Giuseppe, Bove, Tiziana, Caramelli, Fabio, Cariello, Claudia, Carpanese, Anna, Clarizia, Luciano, Comis, Marco, Conte, Massimiliano, Covello, Remo D., De Santis, Vincenzo, Feltracco, Paolo, Giordano, Gianbeppe, Pittarello, Demetrio, Gottin, Leonardo, Guarracino, Fabio, Morelli, Andrea, Musu, Mario, Pala, Giovanni, Pasin, Laura, Pezzoli, Ivana, Paternoster, Gianluca, Remedi, Rossella, Roasio, Agostino, Zucchetti, Mariachiara, Petrini, Flavia, Finco, Gabriele, Ranieri, Marco, and Zangrillo, Alberto

Published
2012
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6. Effect of Fenoldopam on Use of Renal Replacement Therapy Among Patients With Acute Kidney Injury After Cardiac Surgery: A Randomized Clinical Trial

Author

Bove, Tiziana, Zangrillo, Alberto, Guarracino, Fabio, Alvaro, Gabriele, Persi, Bruno, Maglioni, Enivarco, Galdieri, Nicola, Comis, Marco, Caramelli, Fabio, Pasero, Daniela C., Pala, Giovanni, Renzini, Massimo, Conte, Massimiliano, Paternoster, Gianluca, Martinez, Blanca, Pinelli, Fulvio, Frontini, Mario, Zucchetti, Maria C., Pappalardo, Federico, Amantea, Bruno, Camata, Annamaria, Pisano, Antonio, Verdecchia, Claudio, Dal Checco, Erika, Cariello, Claudia, Faita, Luana, Baldassarri, Rubia, Scandroglio, Anna M., Saleh, Omar, Lembo, Rosalba, Calabrò, Maria G., Bellomo, Rinaldo, and Landoni, Giovanni

Published
2014
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7. Tracing Changes in Shape of Historical Artefacts Across Time Using 3D Scans: A New Computational Approach.

Author

PALA, GIOVANNI MARIA and COSTINER, LISANDRA S.

Subjects
ANTIQUITIES, DIGITAL humanities, MUSEUM studies, SEMANTICS, CULTURAL property
Abstract

This paper pioneers a new computational approach for the study of changes in shape of objects across time. Previously, such a study was undertaken by scholars using a purely visual approach and relied on images of objects or in-person observations. This paper’s approach is based on 3D scans of historical artefacts. Sample points are extracted from these 3D scans and the distance between analogous points across different objects is computed using an approximation of the Wasserstein metric, namely the Sinkhorn distance. In this paper, the approach is demonstrated on a small set of ancient Greek vessels of the Krater, Pelike, and Kylix types, as the variation in their shapes across time is well known to archaeologists. Results offer, for the first time, a way of quantifying differences between objects. Benefits of this approach lie in its ability to quantify change, to study complex 3D material, and to analyse large datasets of objects, opening the possibility of constructing new large-scale studies of object shape across time and geographical regions. These have a range of applications in art history, archaeology, digital humanities, museology and extended reality studies. [ABSTRACT FROM AUTHOR]

Published
2022
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8. A randomized controlled trial of levosimendan to reduce mortality in high-risk cardiac surgery patients (CHEETAH): Rationale and design.

Author

Zangrillo, Alberto, Alvaro, Gabriele, Pisano, Antonio, Guarracino, Fabio, Lobreglio, Rosetta, Bradic, Nikola, Lembo, Rosalba, Gianni, Stefano, Calabrò, Maria Grazia, Likhvantsev, Valery, Grigoryev, Evgeny, Buscaglia, Giuseppe, Pala, Giovanni, Auci, Elisabetta, Amantea, Bruno, Monaco, Fabrizio, De Vuono, Giovanni, Corcione, Antonio, Galdieri, Nicola, and Cariello, Claudia

Abstract

Objective: Patients undergoing cardiac surgery are at risk of perioperative low cardiac output syndrome due to postoperative myocardial dysfunction. Myocardial dysfunction in patients undergoing cardiac surgery is a potential indication for the use of levosimendan, a calcium sensitizer with 3 beneficial cardiovascular effects (inotropic, vasodilatory, and anti-inflammatory), which appears effective in improving clinically relevant outcomes.Design: Double-blind, placebo-controlled, multicenter randomized trial.Setting: Tertiary care hospitals.Interventions: Cardiac surgery patients (n = 1,000) with postoperative myocardial dysfunction (defined as patients with intraaortic balloon pump and/or high-dose standard inotropic support) will be randomized to receive a continuous infusion of either levosimendan (0.05-0.2 μg/[kg min]) or placebo for 24-48 hours.Measurements and Main Results: The primary end point will be 30-day mortality. Secondary end points will be mortality at 1 year, time on mechanical ventilation, acute kidney injury, decision to stop the study drug due to adverse events or to start open-label levosimendan, and length of intensive care unit and hospital stay. We will test the hypothesis that levosimendan reduces 30-day mortality in cardiac surgery patients with postoperative myocardial dysfunction.Conclusions: This trial is planned to determine whether levosimendan could improve survival in patients with postoperative low cardiac output syndrome. The results of this double-blind, placebo-controlled randomized trial may provide important insights into the management of low cardiac output in cardiac surgery. [ABSTRACT FROM AUTHOR]

Published
2016
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