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Introduction: The goal of this research is to identify the factors that negatively impact the achievement of the minimum clinically significant change (MCID) for the American Shoulder and Elbow Surgeons (ASES) score within the realm of various orthopedic shoulder procedures. Methods: We conducted a comprehensive review of studies published from 2002 to 2023, utilizing OvidMedline and PubMed databases. Our search criteria included terms such as "minimal clinically important difference" or "MCID" along with associated MeSH terms, in addition to "American shoulder and elbow surgeon" or "ASES." We selectively included primary investigations that assessed factors linked to the failure to achieve MCID for the ASES score subsequent to orthopedic shoulder procedures, while excluding papers addressing anatomical, surgical, or injury-related aspects. Results: Our analysis identified 149 full-text articles, leading to the inclusion of 12 studies for detailed analysis. The selected studies investigated outcomes following various orthopedic shoulder procedures, encompassing biceps tenodesis, total shoulder arthroplasty, and rotator cuff repair. Notably, factors, such as gender, body mass index, diabetes, smoking habits, opioid usage, depression, anxiety, workers' compensation, occupational satisfaction, and the preoperative ASES score, were all associated with the inability to attain MCID. Conclusion: In summary, numerous factors exert a negative influence on the attainment of MCID following shoulder procedures, and these factors appear to be irrespective of the specific surgical technique employed. Patients presenting with these factors may perceive their surgical outcomes as less successful when compared to those without these factors. Identifying these factors can enable healthcare providers to provide more effective counseling to patients regarding their expected outcomes and rehabilitation course. Furthermore, these findings can aid in the development of a screening tool to better identify these risk factors and optimize them before surgery. [ABSTRACT FROM AUTHOR]

Managing osteophyte in elbow osteoarthritis (OA) is not an easy task. In the review of the subject hereby, the molecular biology and biomechanics of osteophyte formation will be addressed in composite detail. A number of basic and clinical science research studies that have evaluated the importance and significant role of growth factors, cytokines production, receptors expression, proteoglycans, and alarmins secretion will be included. At the same time, it is notable that the osteophyte formation has not been thoroughly evaluated with respect to its biomechanics, stress and strain pattern on the joint, and its relation to growth plate and the differences that may exist between animal and human joints. Namely, a few studies have begun to look at this particular aspect of osteophyte formation, which does not cover the issue of the graded biomechanical response to the osteophyte formation. The findings of this study can conclude that biomechanical understanding of osteophyte formation has the potential to give a better solution for medical and surgical management of osteophyte formation in different joints and particularly in elbow joint. As such, the proper management of elbow OA with its significant osteophyte formation requires a comprehensive understanding of biology and biomechanics of osteophyte formation. [ABSTRACT FROM AUTHOR]