Search

Your search keyword '"Obuchowski, Nancy A"' showing total 383 results
Start Over Author "Obuchowski, Nancy A" Search Limiters Peer Reviewed
383 results on '"Obuchowski, Nancy A"'

2. METhodological RadiomICs Score (METRICS): a quality scoring tool for radiomics research endorsed by EuSoMII

Author

Kocak, Burak, Akinci D’Antonoli, Tugba, Mercaldo, Nathaniel, Alberich-Bayarri, Angel, Baessler, Bettina, Ambrosini, Ilaria, Andreychenko, Anna E., Bakas, Spyridon, Beets-Tan, Regina G. H., Bressem, Keno, Buvat, Irene, Cannella, Roberto, Cappellini, Luca Alessandro, Cavallo, Armando Ugo, Chepelev, Leonid L., Chu, Linda Chi Hang, Demircioglu, Aydin, deSouza, Nandita M., Dietzel, Matthias, Fanni, Salvatore Claudio, Fedorov, Andrey, Fournier, Laure S., Giannini, Valentina, Girometti, Rossano, Groot Lipman, Kevin B. W., Kalarakis, Georgios, Kelly, Brendan S., Klontzas, Michail E., Koh, Dow-Mu, Kotter, Elmar, Lee, Ho Yun, Maas, Mario, Marti-Bonmati, Luis, Müller, Henning, Obuchowski, Nancy, Orlhac, Fanny, Papanikolaou, Nikolaos, Petrash, Ekaterina, Pfaehler, Elisabeth, Pinto dos Santos, Daniel, Ponsiglione, Andrea, Sabater, Sebastià, Sardanelli, Francesco, Seeböck, Philipp, Sijtsema, Nanna M., Stanzione, Arnaldo, Traverso, Alberto, Ugga, Lorenzo, Vallières, Martin, van Dijk, Lisanne V., van Griethuysen, Joost J. M., van Hamersvelt, Robbert W., van Ooijen, Peter, Vernuccio, Federica, Wang, Alan, Williams, Stuart, Witowski, Jan, Zhang, Zhongyi, Zwanenburg, Alex, and Cuocolo, Renato

Published
2024
Full Text
View/download PDF

3. Artificial intelligence and radiologists in prostate cancer detection on MRI (PI-CAI): an international, paired, non-inferiority, confirmatory study

Author

Saha, Anindo, Bosma, Joeran S., Twilt, Jasper J., van Ginneken, Bram, Noordman, Constant R., Slootweg, Ivan, Roest, Christian, Fransen, Stefan J., Sunoqrot, Mohammed R.S., Bathen, Tone F., Rouw, Dennis, Immerzeel, Jos, Geerdink, Jeroen, van Run, Chris, Groeneveld, Miriam, Meakin, James, Karagöz, Ahmet, Bône, Alexandre, Routier, Alexandre, Marcoux, Arnaud, Abi-Nader, Clément, Li, Cynthia Xinran, Feng, Dagan, Alis, Deniz, Karaarslan, Ercan, Ahn, Euijoon, Nicolas, François, Sonn, Geoffrey A., Bhattacharya, Indrani, Kim, Jinman, Shi, Jun, Jahanandish, Hassan, An, Hong, Kan, Hongyu, Oksuz, Ilkay, Qiao, Liang, Rohé, Marc-Michel, Yergin, Mert, Khadra, Mohamed, Şeker, Mustafa E., Kartal, Mustafa S., Debs, Noëlie, Fan, Richard E., Saunders, Sara, Soerensen, Simon J.C., Moroianu, Stefania, Vesal, Sulaiman, Yuan, Yuan, Malakoti-Fard, Afsoun, Mačiūnien, Agnė, Kawashima, Akira, de Sousa Machadov, Ana M.M. de M.G., Moreira, Ana Sofia L., Ponsiglione, Andrea, Rappaport, Annelies, Stanzione, Arnaldo, Ciuvasovas, Arturas, Turkbey, Baris, de Keyzer, Bart, Pedersen, Bodil G., Eijlers, Bram, Chen, Christine, Riccardo, Ciabattoni, Courrech Staal, Ewout F.W., Jäderling, Fredrik, Langkilde, Fredrik, Aringhieri, Giacomo, Brembilla, Giorgio, Son, Hannah, Vanderlelij, Hans, Raat, Henricus P.J., Pikūnienė, Ingrida, Macova, Iva, Schoots, Ivo, Caglic, Iztok, Zawaideh, Jeries P., Wallström, Jonas, Bittencourt, Leonardo K., Khurram, Misbah, Choi, Moon H., Takahashi, Naoki, Tan, Nelly, Franco, Paolo N., Gutierrez, Patricia A., Thimansson, Per Erik, Hanus, Pieter, Puech, Philippe, Rau, Philipp R., de Visschere, Pieter, Guillaume, Ramette, Cuocolo, Renato, Falcão, Ricardo O., van Stiphout, Rogier S.A., Girometti, Rossano, Briediene, Ruta, Grigienė, Rūta, Gitau, Samuel, Withey, Samuel, Ghai, Sangeet, Penzkofer, Tobias, Barrett, Tristan, Tammisetti, Varaha S., Løgager, Vibeke B., Černý, Vladimír, Venderink, Wulphert, Law, Yan M., Lee, Young J., Bjartell, Anders, Padhani, Anwar R., Bonekamp, David, Villeirs, Geert, Salomon, Georg, Giannarini, Gianluca, Kalpathy-Cramer, Jayashree, Barentsz, Jelle, Maier-Hein, Klaus H., Rusu, Mirabela, Obuchowski, Nancy A., Rouvière, Olivier, van den Bergh, Roderick, Panebianco, Valeria, Kasivisvanathan, Veeru, Yakar, Derya, Elschot, Mattijs, Veltman, Jeroen, Fütterer, Jurgen J., de Rooij, Maarten, Huisman, Henkjan, Bosma, Joeran S, Twilt, Jasper J, Padhani, Anwar R, Maier-Hein, Klaus H, Obuchowski, Nancy A, and Fütterer, Jurgen J

Published
2024
Full Text
View/download PDF

4. Evaluating Biparametric Versus Multiparametric Magnetic Resonance Imaging for Diagnosing Clinically Significant Prostate Cancer: An International, Paired, Noninferiority, Confirmatory Observer Study

Author

Twilt, Jasper J., Saha, Anindo, Bosma, Joeran S., van Ginneken, Bram, Noordman, Constant R., Slootweg, Ivan, Roest, Christian, Fransen, Stefan J., Sunoqrot, Mohammed R.S., Bathen, Tone F., Rouw, Dennis, Geerdink, Jeroen, van Run, Chris, Groeneveld, Miriam, Meakin, James, Immerzeel, Jos J.F.M., Yakar, Derya, Elschot, Mattijs, Veltman, Jeroen, Fütterer, Jurgen J., de Rooij, Maarten, Huisman, Henkjan, Bjartell, Anders, Padhani, Anwar R., Bonekamp, David, Villeirs, Geert, Salomon, Georg, Giannarini, Gianluca, Kalpathy-Cramer, Jayashree, Barentsz, Jelle, Maier-Hein, Klaus H., Rusu, Mirabela, Obuchowski, Nancy A., Rouviere, Olivier, van den Bergh, Roderick, Panebianco, Valeria, Kasivisvanathan, Veeru, Malakoti-Fard, Afsoun, Mačiūnien, Agnė, Kawashima, Akira, Gaivão, Ana M., Moreira, Ana S.L., Ponsiglione, Andrea, Rappaport, Annelies, Stanzione, Arnaldo, Ciuvasovas, Arturas, Turkbey, Baris, Keyzer, Bart De, Pedersen, Bodil G., Eijlers, Bram, Chen, Christine, Riccardo, Ciabattoni, Alis, Deniz, Courrech Staal, Ewout F.W., Thimansson, Erik, Jäderling, Fredrik, Langkilde, Fredrik, Aringhieri, Giacomo, Brembilla, Giorgio, Son, Hannah, van der Lelij, Hans, Raat, Henricus P.J., Pikūnienė, Ingrida, Macova, Iva, Schoots, Ivo, Caglic, Iztok, Zawaideh, Jeries P., Wallström, Jonas, Bittencourt, Leonardo K., Khurram, Misbah, Choi, Moon Hyung, Takahashi, Naoki, Tan, Nelly, Franco, Paolo N., Gutierrez, Patricia A., Hanus, Petr, Puech, Philippe, Rau, Philipp R., de Visschere, Pieter, Guillaume, Ramette, Cuocolo, Renato, Falcão, Ricardo O., van Stiphout, Rogier S.A., Girometti, Rossano, Briediene, Ruta, Grigienė, Rūta, Gitau, Samuel, Withey, Samuel, Ghai, Sangeet, Penzkofer, Tobias, Barrett, Tristan, Tammisetti, Varaha Sai, Løgager, Vibeke B., Černý, Vladimír, Venderink, Wulphert, Law, Yan Mee, Lee, Young Joon, and Rouvière, Olivier

Published
2025
Full Text
View/download PDF

6. Special Report on the Consensus QIBA Profile for Objective Analytical Validation of Non-calcified and High-risk Plaque and Other Biomarkers using Computed Tomography Angiography

Author

Buckler, Andrew J., Abbara, Suhny, Budoff, Matthew J., Carr, John Jeffrey, De Cecco, Carlo N., DeMarco, J. Kevin, Ferencik, Maros, Figtree, Gemma A., Ikuta, Ichiro, Kolossváry, Márton, Konrad, Mathis, Lal, Brajesh K., Marques, Hugo, Moss, Alastair J., Obuchowski, Nancy A., van Beek, Edwin J.R., Virmani, Renu, Williams, Michelle C., Saba, Luca, and Joseph Schoepf, U.

Published
2024
Full Text
View/download PDF

7. 18F-fluciclovine PET/CT to distinguish radiation necrosis from tumor progression for brain metastases treated with radiosurgery: results of a prospective pilot study

Author

Tom, Martin C., DiFilippo, Frank P., Jones, Stephen E., Suh, John H., Obuchowski, Nancy A., Smile, Timothy D., Murphy, Erin S., Yu, Jennifer S., Barnett, Gene H., Angelov, Lilyana, Mohammadi, Alireza M., Huang, Steve S., Wu, Guiyun, Johnson, Scott, Peereboom, David M., Stevens, Glen H. J., Ahluwalia, Manmeet S., and Chao, Samuel T.

Published
2023
Full Text
View/download PDF

36. Algorithm Variability in the Estimation of Lung Nodule Volume From Phantom CT Scans: Results of the QIBA 3A Public Challenge

Author

Athelogou, Maria, Kim, Hyun J., Dima, Alden, Obuchowski, Nancy, Peskin, Adele, Gavrielides, Marios A., Petrick, Nicholas, Saiprasad, Ganesh, Colditz Colditz, Dirk, Beaumont, Hubert, Oubel, Estanislao, Tan, Yongqiang, Zhao, Binsheng, Kuhnigk, Jan-Martin, Moltz, Jan Hendrik, Orieux, Guillaume, Gillies, Robert J., Gu, Yuhua, Mantri, Ninad, Goldmacher, Gregory, Zhang, Luduan, Vega, Emilio, Bloom, Michael, Jarecha, Rudresh, Soza, Grzegorz, Tietjen, Christian, Takeguchi, Tomoyuki, Yamagata, Hitoshi, Peterson, Sam, Masoud, Osama, and Buckler, Andrew J.

Published
2016
Full Text
View/download PDF

38. Repeatability of 18F-FDG uptake in metastatic bone lesions of breast cancer patients and implications for accrual to clinical trials.

Author

Muzi, Mark, Peterson, Lanell M., Specht, Jennifer M., Hippe, Daniel S., Novakova-Jiresova, Alena, Lee, Jean H., Kurland, Brenda F., Mankoff, David A., Obuchowski, Nancy, Linden, Hannah M., and Kinahan, Paul E.

Subjects
CANCER patients, STERNUM, BREAST cancer, CLINICAL trials, PROGRESSION-free survival, CONFIDENCE intervals, MAGNETIC resonance mammography, STATISTICAL reliability
Abstract

Background: Standard measures of response such as Response Evaluation Criteria in Solid Tumors are ineffective for bone lesions, often making breast cancer patients that have bone-dominant metastases ineligible for clinical trials with potentially helpful therapies. In this study we prospectively evaluated the test-retest uptake variability of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) in a cohort of breast cancer patients with bone-dominant metastases to determine response criteria. The thresholds for 95% specificity of change versus no-change were then applied to a second cohort of breast cancer patients with bone-dominant metastases. Methods: For this study, nine patients with 38 bone lesions were imaged with 18F-FDG in the same calibrated scanner twice within 14 days. Tumor uptake was quantified by the most commonly used PET parameter, the maximum tumor voxel normalized by dose and body weight (SUVmax) and also by the mean of a 1-cc maximal uptake volume normalized by dose and lean-body-mass (SULpeak). The asymmetric repeatability coefficients with confidence intervals for SUVmax and SULpeak were used to determine the limits of 18F-FDG uptake variability. A second cohort of 28 breast cancer patients with bone-dominant metastases that had 146 metastatic bone lesions was imaged with 18F-FDG before and after standard-of-care therapy for response assessment. Results: The mean relative difference of SUVmax and SULpeak in 38 bone tumors of the first cohort were 4.3% and 6.7%. The upper and lower asymmetric limits of the repeatability coefficient were 19.4% and − 16.3% for SUVmax, and 21.2% and − 17.5% for SULpeak. 18F-FDG repeatability coefficient confidence intervals resulted in the following patient stratification using SULpeak for the second patient cohort: 11-progressive disease, 5-stable disease, 7-partial response, and 1-complete response with three inevaluable patients. The asymmetric repeatability coefficients response criteria for SULpeak changed the status of 3 patients compared to the standard Positron Emission Tomography Response Criteria in Solid Tumors of ± 30% SULpeak. Conclusion: In evaluating bone tumor response for breast cancer patients with bone-dominant metastases using 18F-FDG SUVmax, the repeatability coefficients from test-retest studies show that reductions of more than 17% and increases of more than 20% are unlikely to be due to measurement variability. Serial 18F-FDG imaging in clinical trials investigating bone lesions in these patients, such as the ECOG-ACRIN EA1183 trial, benefit from confidence limits that allow interpretation of response. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

39. Visceral adipose tissue volume effect in Crohn's disease using reduced exposure CT enterography.

Author

Hunter, Sara A., Baker, Mark E., Ream, Justin M., Sweet, David E., Austin, Nicholas A., Remer, Erick M., Primak, Andrew, Bullen, Jennifer, Obuchowski, Nancy, Karim, Wadih, and Herts, Brian R.

Subjects
CROHN'S disease, ADIPOSE tissues, NOSOLOGY, SMALL intestine
Abstract

Purpose: The purpose of this investigation was to assess the effect of visceral adipose tissue volume (VA) on reader efficacy in diagnosing and characterizing small bowel Crohn's disease using lower exposure CT enterography (CTE). Secondarily, we investigated the effect of lower exposure and VA on reader diagnostic confidence. Methods: Prospective paired investigation of 256 CTE, 129 with Crohn's disease, were reconstructed at 100% and simulated 50% and 30% exposure. The senior author provided the disease classification for the 129 patients with Crohn's disease. Patient VA was measured, and exams were evaluated by six readers for presence or absence of Crohn's disease and phenotype using a 0–10‐point scale. Logistic regression models assessed the effect of VA on sensitivity and specificity. Results: The effect of VA on sensitivity was significantly reduced at 30% exposure (odds radio [OR]: 1.00) compared to 100% exposure (OR: 1.12) (p = 0.048). There was no statistically significant difference among the exposures with respect to the effect of visceral fat on specificity (p = 0.159). The study readers' probability of agreement with the senior author on disease classification was 60%, 56%, and 53% at 100%, 50%, and 30% exposure, respectively (p = 0.004). When detecting low severity Crohn's disease, readers' mean sensitivity was 83%, 75%, and 74% at 100%, 50%, and 30% exposure, respectively (p = 0.002). In low severity disease, sensitivity also tended to increase as visceral fat increased (ORs per 1000 cm3 increase in visceral fat: 1.32, 1.31, and 1.18, p = 0.010, 0.016, and 0.100, at 100%, 50%, and 30% exposure). Conclusions: While the interaction is complex, VA plays a role in detecting and characterizing small bowel Crohn's disease when exposure is altered, particularly in low severity disease. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

41. Inter-Method Performance Study of Tumor Volumetry Assessment on Computed Tomography Test-Retest Data

Author

Buckler, Andrew J., Danagoulian, Jovanna, Johnson, Kjell, Peskin, Adele, Gavrielides, Marios A., Petrick, Nicholas, Obuchowski, Nancy A., Beaumont, Hubert, Hadjiiski, Lubomir, Jarecha, Rudresh, Kuhnigk, Jan-Martin, Mantri, Ninad, McNitt-Gray, Michael, Moltz, Jan H., Nyiri, Gergely, Peterson, Sam, Tervé, Pierre, Tietjen, Christian, von Lavante, Etienne, Ma, Xiaonan, St. Pierre, Samantha, and Athelogou, Maria

Published
2015
Full Text
View/download PDF

45. Meniscal Treatment as a Predictor of Worse Articular Cartilage Damage on MRI at 2 Years After ACL Reconstruction: The MOON Nested Cohort

Author

Altahawi, Faysal, Reinke, Emily K, Briskin, Isaac, Cantrell, William A, Flanigan, David C, Fleming, Braden C, Huston, Laura J, Li, Xiaojuan, Oak, Sameer, Obuchowski, Nancy A, Scaramuzza, Erica A, Winalski, Carl S, Zajichek, Alex, Spindler, Kurt P, and Jones, Morgan H

Subjects
Adult, Cartilage, Articular, Adolescent, Anterior Cruciate Ligament Injuries, Physical Therapy, Sports Therapy and Rehabilitation, musculoskeletal system, Magnetic Resonance Imaging, Article, Cohort Studies, Orthopedics, Humans, Female, Meniscus, Orthopedics and Sports Medicine, Prospective Studies
Abstract

Background: Patients undergoing anterior cruciate ligament reconstruction (ACLR) are at an increased risk for posttraumatic osteoarthritis (PTOA). While we have previously shown that meniscal treatment with ACLR predicts more radiographic PTOA at 2 to 3 years postoperatively, there are a limited number of similar studies that have assessed cartilage directly with magnetic resonance imaging (MRI). Hypothesis: Meniscal repair or partial meniscectomy at the time of ACLR independently predicts more articular cartilage damage on 2- to 3-year postoperative MRI compared with a healthy meniscus or a stable untreated tear. Study Design: Cohort study; Level of evidence, 2. Methods: A consecutive series of patients undergoing ACLR from 1 site within the prospective, nested Multicenter Orthopaedic Outcomes Network (MOON) cohort underwent bilateral knee MRI at 2 to 3 years postoperatively. Patients were aged Results: The cohort included 60 patients (32 female; median age, 18.7 years). Concomitant meniscal treatment at the time of index ACLR was performed in 17 medial menisci (13 meniscal repair and 4 partial meniscectomy) and 27 lateral menisci (3 meniscal repair and 24 partial meniscectomy). Articular cartilage damage was worse in the ipsilateral reconstructed knee ( P < .001). A meniscal injury requiring surgical treatment with ACLR predicted a worse CDS for medial meniscal treatment (medial compartment CDS: P = .005; whole joint CDS: P < .001) and lateral meniscal treatment (lateral compartment CDS: P = .038; whole joint CDS: P = .863). Other predictors of a worse relative CDS included age for the medial compartment ( P < .001), surgically observed articular cartilage damage for the patellofemoral compartment ( P = .048), and body mass index ( P = .007) and age ( P = .020) for the whole joint. Conclusion: A meniscal injury requiring surgical treatment with partial meniscectomy or meniscal repair at the time of ACLR predicted worse articular cartilage damage on MRI at 2 to 3 years after surgery. Further research is required to differentiate between the effects of partial meniscectomy and meniscal repair.

Published
2022
Full Text
View/download PDF

50. The Effect of Aspiration and Corticosteroid Injection After ACL Injury on Postoperative Infection Rate.

Author

Cantrell, William A., Cox, Charles L., Johnson, Carrie, Obuchowski, Nancy, Strnad, Greg, Swinehart, Dane, Yalcin, Sercan, and Spindler, Kurt P.

Subjects
ADRENOCORTICAL hormones, INJECTIONS, HOMOGRAFTS, CONFIDENCE intervals, RESPIRATORY aspiration, TIME, SURGICAL complications, DISEASE incidence, RETROSPECTIVE studies, ACQUISITION of data, MANN Whitney U Test, RISK assessment, ANTERIOR cruciate ligament injuries, SURGICAL site infections, MEDICAL records, DESCRIPTIVE statistics, ANTERIOR cruciate ligament surgery, SPORTS medicine, BODY mass index, LONGITUDINAL method, DISEASE risk factors
Abstract

Background: Injecting bioactive substances into the knee is common in orthopaedic practice, and recently it has been shown to mitigate risk factors for posttraumatic osteoarthritis. Therefore, understanding the influence of these injections on postoperative infection rate is imperative. Hypothesis: Postinjury aspiration and corticosteroid injection (CSI) of the knee before anterior cruciate ligament (ACL) reconstruction (ACLR) would not increase the risk of postoperative infection. Study Design: Cohort Study; Level of evidence, 3. Methods: All patients between the ages of 10 and 65 years who underwent primary bone–patellar tendon–bone ACLR by 1 fellowship-trained sports medicine orthopaedic surgeon between January 1, 2011, and September 8, 2020, at 1 of 2 major academic centers were evaluated for inclusion. A total of 693 patients were included, with 273 patients receiving postinjury and preoperative aspiration and CSI. A postoperative infection was defined as a patient returning to the operating room for an intra-articular washout. The intervals—measured in days—between the CSI and ACLR and between ACLR and the final follow-up were recorded. To further evaluate the infection risk in each cohort (total cohort; aspiration and injection cohort; no aspiration and injection cohort), the upper 95% confidence bound for the infection risk was calculated for each cohort. Results: There were no postoperative infections in the 693 patients included in this study. The upper 95% confidence bounds were 0.4%, 1.1%, and 0.7% for the total cohort, the cohort that underwent aspiration and injection, and the cohort that did not, respectively. The median number of days between the surgical date and that of the aspiration and injection was 34 days, and the mean follow-up for the entire cohort was 337.4 days (95% CI, 307.6-367.3). Conclusion: Postinjury and preoperative aspiration and CSI is a safe intervention that can be used before ACLR. Future studies with larger sample sizes, longer patient follow-ups, and multiple surgeons would be helpful to both better understand infection risk and better identify the influence of CSI on preventing posttraumatic osteoarthritis. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results