323 results on '"Nepom, Gerald"'
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2. Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue
3. A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab
4. Donor-specific immune senescence as a candidate biomarker of operational tolerance following liver transplantation in adults: Results of a prospective, multicenter cohort study
5. C-peptide and metabolic outcomes in trials of disease modifying therapy in new-onset type 1 diabetes: an individual participant meta-analysis
6. Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy
7. Incorporating genetics in identifying peanut allergy risk and tailoring allergen immunotherapy: A perspective on the genetic findings from the LEAP trial
8. Epidermal differentiation complex genetic variation in atopic dermatitis and peanut allergy
9. Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: A randomized controlled trial
10. Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy
11. Evolving Concepts in Pathophysiology, Screening, and Prevention of Type 1 Diabetes: Report of Diabetes Mellitus Interagency Coordinating Committee Workshop.
12. Interconnected lineage trajectories link conventional and natural killer (NK)-like exhausted CD8+ T cells beneficial in type 1 diabetes.
13. Synchronous immune alterations mirror clinical response during allergen immunotherapy
14. De novo Generation of Antigen-Specific ( CD4 + CD25 + ) Regulatory T Cells from Human ( CD4 + CD25 - ) Cells
15. Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 diabetes
16. Identification and Modulation of a Naturally Processed T Cell Epitope from the Diabetes-Associated Autoantigen Human Glutamic Acid Decarboxylase 65 (hGAD65)
17. Critical Contribution of β Chain Residue 57 in Peptide Binding Ability of Both HLA-DR and -DQ Molecules
18. Ancestral Major Histocompatibility Complex DRB Genes Beget Conserved Patterns of Localized Polymorphisms
19. A Contra Capture Protein Array Platform for Studying Post-translationally Modified (PTM) Auto-antigenomes
20. Obstacles and opportunities for targeting the effector T cell response in type 1 diabetes
21. Correlation Among Hypoglycemia, Glycemic Variability, and C-Peptide Preservation After Alefacept Therapy in Patients with Type 1 Diabetes Mellitus: Analysis of Data from the Immune Tolerance Network T1DAL Trial
22. Adult-onset type 1 diabetes patients display decreased IGRP-specific Tr1 cells in blood
23. Biomarkers for antigen immunotherapy in allergy and type 1 diabetes
24. Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity
25. Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial
26. Anti-cytokine therapies in T1D: Concepts and strategies
27. Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope
28. Systems Scale Interactive Exploration Reveals Quantitative and Qualitative Differences in Response to Influenza and Pneumococcal Vaccines
29. A functional framework for interpretation of genetic associations in T1D
30. Hyaluronan and versican in the control of human T-lymphocyte adhesion and migration
31. ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors
32. HLA-associated outcomes in peanut oral immunotherapy trials identify mechanistic and clinical determinants of therapeutic success
33. Kv1.3 Channels Are a Therapeutic Target for T Cell-Mediated Autoimmune Diseases
34. DRB1*0401-Restricted Human T Cell Clone Specific for the Major Proinsulin73-90 Epitope Expresses a Down-Regulatory T Helper 2 Phenotype
35. Prediction and Pathogenesis in Type 1 Diabetes
36. Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients
37. H5N1 strain-specific Hemagglutinin CD4+ T cell epitopes restricted by HLA DR4
38. Changes in autoreactive T cell avidity during type 1 diabetes development
39. Omics-oriented research illustrated with the LEAP study and the OASIS bioinformatics tool.
40. Molecular Diversity of HLA-DR4 Haplotypes
41. Identification of a Polymorphic Variant Associated with HLA-DQw3 and Characterized by Specific Restriction Sites within the DQ β -Chain Gene
42. A Specific HLA-DPβ Allele is Associated with Pauciarticular Juvenile Rheumatoid Arthritis but not Adult Rheumatoid Arthritis
43. Structural Requirements for Recognition of the HLA-Dw14 Class II Epitope: A Key HLA Determinant Associated with Rheumatoid Arthritis
44. Mutational Analysis of the HLA-DQ3.2 Insulin-Dependent Diabetes Mellitus Susceptibility Gene
45. An Extended HLA-D Region Haplotype Associated with Celiac Disease
46. Induction of Immunity to a Human Tumor Marker by in vivo Administration of Anti-Idiotypic Antibodies in Mice
47. Electrophoretic Analysis of Human HLA-DR Antigens from HLA-DR4 Homozygous Cell Lines: Correlation between β -Chain Diversity and HLA-D
48. HLA-DR Class II Associations with Rubella Vaccine-Induced Joint Manifestations
49. Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation
50. Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice
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