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Glucose is an obligate metabolic fuel for the brain under physiologic conditions. If glucose levels decreases to a certain limit, can lead to neuroglycopenic symtoms(due to deprivation of glucose to CNS) and those attributable to the autonomic nervous system activation triggered by hypoglycemia (neurogenic or autonomic symptoms) .Students often complain about inability to concentrate and other symptoms of hypoglycemia in lectures which immediately precedes the lunch hour. This study investigates whether hypoglycemic symptoms are associated with decrease blood glucose levels in young healthy medical students. A cross sectional study was conducted in 100 medical students between the age group 18-24 years of either gender. On the day of examination, subjects were instructed to have breakfast at 8:00am.At 1:00pm blood glucose levels were measured and a questionnaire prepared on likert scale was given to assess hypoglycemic symptoms. The subjects were divided in to two groups depending on blood glucose levels:Group I : < 80 mg/dl Group II : > 80 mg/dl. Analysis of data have shown that Group I subjects had significant hypoglycemic symptoms like hungerpangs,lack of concentration,headache as compared to Group II. The study concluded that Variations in hypoglycaemic symptoms during the pre prandial period are present and do not require exponentially low blood glucose levels. Non-specific hypoglycaemic symptoms tend to occur and should not be attributed to low blood glucose levels. [ABSTRACT FROM AUTHOR]

Abstract: It is not known whether the extent of the improvement in lipids and lipoproteins on a high–cis-monounsaturated (high-mono) diet compared with a high-carbohydrate (high-carb) diet is different in patients with type 2 diabetes mellitus (T2DM) and nondiabetic subjects. The aim of this study is to compare the effect of a high-mono and a high-carb diet on lipids and lipoproteins in patients with T2DM and nondiabetic subjects. Ten healthy nondiabetic men, 8 men with T2DM on dietary therapy alone, and 10 men with T2DM requiring insulin therapy were fed an isoenergic high-carb diet (60% energy as carbohydrate and 25% as fat) and a high-mono diet (50% energy as fat and 35% as carbohydrate) for 2 to 4 weeks in a randomized, crossover fashion. Dietary fiber, simple carbohydrates, and cholesterol were held constant across diets. The lipid and lipoprotein responses to these diets were compared in nondiabetic and T2DM subjects by repeated measures analysis of variance model. Patients with T2DM had 2.2 to 2.3 times greater reductions in plasma triacylglycerol, very low-density lipoprotein (VLDL) cholesterol, and total cholesterol/high-density lipoprotein cholesterol ratio (TC/HDLC) on the high-mono diet compared with the high-carb diet than the nondiabetic subjects (P = .02-.04). The reductions in triacylglycerol and VLDL cholesterol were 2.7 times greater (P = .009-.02) in T2DM subjects with high plasma triacylglycerol concentrations (>2.26 mmol/L) but only 1.4 to 2.0 times greater (P = .16-.52) in T2DM patients with low triacylglycerol concentrations (<2.26 mmol/L) compared with nondiabetic subjects who all had low triacylglycerol concentrations (<2.26 mmol/L). Patients with T2DM experienced greater decreases in plasma triacylglycerol, VLDL cholesterol, and TC/HDLC on a high-mono diet compared with a high-carb diet than nondiabetic subjects. The extents of the improvements were likely related to plasma triacylglycerol concentrations in patients with T2DM. [Copyright &y& Elsevier]