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Your search keyword '"Moericke, Anja"' showing total 25 results
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25 results on '"Moericke, Anja"'

1. CD371-positive pediatric B-cell acute lymphoblastic leukemia: propensity to lineage switch and slow early response to treatment

Author

Buldini, Barbara, Varotto, Elena, Maurer-Granofszky, Margarita, Gaipa, Giuseppe, Schumich, Angela, Brüggemann, Monika, Mejstrikova, Ester, Cazzaniga, Giovanni, Hrusak, Ondrej, Szczepanowski, Monika, Scarparo, Pamela, Zimmermann, Martin, Strehl, Sabine, Schinnerl, Dagmar, Zaliova, Marketa, Karawajew, Leonid, Bourquin, Jean-Pierre, Feuerstein, Tamar, Cario, Gunnar, Alten, Julia, Möricke, Anja, Biffi, Alessandra, Parasole, Rosanna, Fagioli, Franca, Valsecchi, Maria Grazia, Biondi, Andrea, Locatelli, Franco, Attarbaschi, Andishe, Schrappe, Martin, Conter, Valentino, Basso, Giuseppe, and Dworzak, Michael N.

Published
2024
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2. Severe toxicity free survival: physician-derived definitions of unacceptable long-term toxicities following acute lymphocytic leukaemia

Author

Attarbaschi, Andishe, Adams, Madeline R, Andres-Jensen, Liv, Bardi, Edit, Barzilai-Birenboim, Shlomit, Baust, Katja, Bhojwani, Deepa, Boesten, Tineke, Calaminus, Gabriele, Conyers, Rachel, Darlington, Anne-Sophie, de Ville, Maëlle, Escherich, Gabriele, Hagleitner, Melanie, Halsey, Christina, Harila-Saari, Arja, Hou, Jen-Yin, Huang, Ting-Huan, Hudson, Melissa, Jeha, Sima, Jenney, Meriel, Kato, Motohiro, Krawczuk-Rybak, Maryna, Kremer, Leontine, Lautem, Melchior, Liu, Hse-Che, Lopez Lopez, Elixabet, Mateos, Marion, Mlynarski, Wojciech, Möricke, Anja, Muszynska-Roslan, Katarzyna, Niinimaki, Riitta, Pieters, Rob, Piette, Caroline, Raetz, Elizabeth, Ronceray, Leila, Schmiegelow, Kjeld, Toro, Claudia, Trahair, Toby, Valsecchi, Maria Grazia, van der Sluis, Inge, van Litsenburg, Raphaële, Vrooman, Lynda, Weinreb, Sigal, Wiener, Andreas, Winick, Naomi, Yano, Michihiro, Yeh, Ting-Chi, Zapotocka, Ester, Andrés-Jensen, Liv, Hagleitner, Melanie M, van Litsenburg, Raphaele R L, Hudson, Melissa M, Kremer, Leontien, Grazia Valsecchi, Maria, and Vrooman, Lynda M

Published
2021
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3. Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets

Author

Hoell, Jessica I., Ginzel, Sebastian, Kuhlen, Michaela, Kloetgen, Andreas, Gombert, Michael, Fischer, Ute, Hein, Daniel, Demir, Salih, Stanulla, Martin, Schrappe, Martin, zur Stadt, Udo, Bader, Peter, Babor, Florian, Schuster, Friedhelm, Strahm, Brigitte, Alten, Julia, Moericke, Anja, Escherich, Gabriele, von Stackelberg, Arend, Thiele, Ralf, McHardy, Alice C., Peters, Christina, Bornhauser, Beat, Bourquin, Jean-Pierre, Krause, Stefan, Enczmann, Juergen, Meyer, Lüder Hinrich, Eckert, Cornelia, Borkhardt, Arndt, and Meisel, Roland

Published
2019
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4. International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia

Author

Hrusak, Ondrej, de Haas, Valerie, Stancikova, Jitka, Vakrmanova, Barbora, Janotova, Iveta, Mejstrikova, Ester, Capek, Vaclav, Trka, Jan, Zaliova, Marketa, Luks, Ales, Bleckmann, Kirsten, Möricke, Anja, Irving, Julie, Konatkowska, Benigna, Alexander, Thomas B., Inaba, Hiroto, Schmiegelow, Kjeld, Stokley, Simone, Zemanova, Zuzana, Moorman, Anthony V., Rossi, Jorge Gabriel, Felice, Maria Sara, Dalla-Pozza, Luciano, Morales, Jessa, Dworzak, Michael, Buldini, Barbara, Basso, Giuseppe, Campbell, Myriam, Cabrera, Maria Elena, Marinov, Neda, Elitzur, Sarah, Izraeli, Shai, Luria, Drorit, Feuerstein, Tamar, Kolenova, Alexandra, Svec, Peter, Kreminska, Olena, Rabin, Karen R., Polychronopoulou, Sophia, da Costa, Elaine, Marquart, Hanne Vibeke, Kattamis, Antonis, Ratei, Richard, Reinhardt, Dirk, Choi, John K., Schrappe, Martin, and Stary, Jan

Published
2018
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5. Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment: a Delphi consensus

Author

Schmiegelow, Kjeld, Attarbaschi, Andishe, Barzilai, Shlomit, Escherich, Gabriele, Frandsen, Thomas Leth, Halsey, Christina, Hough, Rachael, Jeha, Sima, Kato, Motohiro, Liang, Der-Cherng, Mikkelsen, Torben Stamm, Möricke, Anja, Niinimäki, Riitta, Piette, Caroline, Putti, Maria Caterina, Raetz, Elizabeth, Silverman, Lewis B, Skinner, Roderick, Tuckuviene, Ruta, van der Sluis, Inge, and Zapotocka, Ester

Published
2016
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6. Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000

Author

Möricke, Anja, Zimmermann, Martin, Valsecchi, Maria Grazia, Stanulla, Martin, Biondi, Andrea, Mann, Georg, Locatelli, Franco, Cazzaniga, Giovanni, Niggli, Felix, Aricò, Maurizio, Bartram, Claus R., Attarbaschi, Andishe, Silvestri, Daniela, Beier, Rita, Basso, Giuseppe, Ratei, Richard, Kulozik, Andreas E., Lo Nigro, Luca, Kremens, Bernhard, Greiner, Jeanette, Parasole, Rosanna, Harbott, Jochen, Caruso, Roberta, von Stackelberg, Arend, Barisone, Elena, Rössig, Claudia, Conter, Valentino, and Schrappe, Martin

Published
2016
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10. Early Relapse in ALL Is Identified by Time to Leukemia in NOD/SCID Mice and Is Characterized by a Gene Signature Involving Survival Pathways

Author

Meyer, Lüder Hinrich, Eckhoff, Sarah Mirjam, Queudeville, Manon, Kraus, Johann Michael, Giordan, Marco, Stursberg, Jana, Zangrando, Andrea, Vendramini, Elena, Möricke, Anja, Zimmermann, Martin, Schrauder, Andre, Lahr, Georgia, Holzmann, Karlheinz, Schrappe, Martin, Basso, Giuseppe, Stahnke, Karsten, Kestler, Hans Armin, te Kronnie, Geertruy, and Debatin, Klaus-Michael

Published
2011
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11. Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia

Author

Zuna, Jan, Moericke, Anja, Arens, Mari, Koehler, Rolf, Panzer-Grümayer, Renate, Bartram, Claus R., Fischer, Susanna, Fronkova, Eva, Zaliova, Marketa, Schrauder, André, Stanulla, Martin, Zimmermann, Martin, Trka, Jan, Stary, Jan, Attarbaschi, Andishe, Mann, Georg, Schrappe, Martin, and Cario, Gunnar

Published
2016
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12. Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

Author

Conter, Valentino, Bartram, Claus R., Valsecchi, Maria Grazia, Schrauder, André, Panzer-Grümayer, Renate, Möricke, Anja, Aricò, Maurizio, Zimmermann, Martin, Mann, Georg, De Rossi, Giulio, Stanulla, Martin, Locatelli, Franco, Basso, Giuseppe, Niggli, Felix, Barisone, Elena, Henze, Günter, Ludwig, Wolf-Dieter, Haas, Oskar A., Cazzaniga, Giovanni, Koehler, Rolf, Silvestri, Daniela, Bradtke, Jutta, Parasole, Rosanna, Beier, Rita, van Dongen, Jacques J.M., Biondi, Andrea, and Schrappe, Martin

Published
2010
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19. Osteonecrosis in children with acute lymphoblastic leukemia at initial diagnosis and prior to any chemotherapy.

Author

Krull, Kathinka, Kunstreich, Marina, Bronsema, Annika, Bleckmann, Kirsten, Classen, Carl-Friedrich, Erdlenbruch, Bernhard, Jorch, Norbert, Kolb, Reinhard, Leipold, Alfred, Moser, Olga, Prokop, Aram, Scheurlen, Wolfram, Steinbach, Daniel, Klasen-Sansone, Janina, Klee, Dirk, Escherich, Gabriele, Moericke, Anja, Schrappe, Martin, Borkhardt, Arndt, and Kuhlen, Michaela

Subjects
LYMPHOBLASTIC leukemia, ACUTE leukemia
Abstract

Osteonecrosis (ON) is a common and debilitating side effect of anti-leukemic treatment in children with acute lymphoblastic leukemia (ALL). However, the impact of leukemia itself on ON development remains elusive. We analyzed 76 children enrolled in the ongoing OPAL trial, who had magnetic resonance imaging (MRI) studies at diagnosis. MRI screening revealed 14 osteonecrotic lesions (5 × hips, 9 × knees) of any grade (I-III) in 7 (9.2%) patients. Six months on, the number of ON per patient increased (1 patient), remained constant (2), and decreased (2). The severity increased from grade I to II in two patients, remained constant (1), completely resolved (2), and decreased from grade III to osteoedema (1). No differences between adolescents initially presenting with/without ON were observed concerning age, pubertal stage, body mass index, leukemia characteristics, and clinical presentation. In MRI screening, a remarkable number of adolescents with ALL present with ON at diagnosis. The course of these ON remains highly unpredictable. [ABSTRACT FROM AUTHOR]

Published
2019
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20. Definition and Prognostic Value of Ph‐like and IKZF1plus Status in Children With Down Syndrome and B‐cell Precursor Acute Lymphoblastic Leukemia.

Author

Palmi, Chiara, Bresolin, Silvia, Junk, Stefanie, Fazio, Grazia, Silvestri, Daniela, Zaliova, Marketa, Oikonomou, Athanasios, Scharov, Katerina, Stanulla, Martin, Moericke, Anja, Zimmermann, Martin, Schrappe, Martin, Buldini, Barbara, Bhatia, Sanil, Borkhardt, Arndt, Saitta, Claudia, Galbiati, Marta, Bardini, Michela, Lo Nigro, Luca, and Conter, Valentino

Published
2023
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22. Osteonecrosis develops independently from radiological leukemic infiltration of bone in adolescents with acute lymphoblastic leukemia – first findings of the OPAL trial.

Author

Krull, Kathinka, Kunstreich, Marina, Klasen-Sansone, Janina, Kloetgen, Andreas, Gruener, Franziska, Escherich, Gabriele, Bleckmann, Kirsten, Moericke, Anja, Schrappe, Martin, Jorch, Norbert, Steinbach, Daniel, Classen, Carl-Friedrich, Guggemos, Andreas, Kolb, Reinhard, Klee, Dirk, Borkhardt, Arndt, and Kuhlen, Michaela

Subjects
OSTEONECROSIS, LYMPHOBLASTIC leukemia treatment, LYMPHOBLASTIC leukemia diagnosis, MAGNETIC resonance imaging, LEUKEMIA, PATIENTS
Abstract

Osteonecrosis (ON) is a debilitating side effect of anti-leukemic treatment. Thus far, the role of leukemic infiltration (LI) of bone is unclear. The first 30 children aged ≥10 years, who were enrolled in the ongoing OPAL trial and had MRI studies at diagnosis and at 6 months, were analyzed. MRI revealed extensive LIs in 24 (80%) patients. The signal abnormalities changed back to a physiological signal in 29 out of 30 children at 6 months. Of the 24 children with LIs at diagnosis, 3 (12.5%) developed ON ≥ II, whereas 4 (66.7%) patients without LIs subsequently developed ON ≥ II (p = .016). No differences between children initially presenting with/without LIs were observed concerning age, pubertal stage, white blood count, immunophenotype, and clinical presentation. Initial radiological LI of bone and, thus, single MRI at diagnosis cannot identify children at high risk of developing radiological ON at 6 months into treatment. [ABSTRACT FROM PUBLISHER]

Published
2017
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24. Pediatric precursor T lymphoblastic leukemia and lymphoblastic lymphoma: Differences in the common regions with loss of heterozygosity at chromosome 6q and their prognostic impact.

Author

Burkhardt, Birgit, Moericke, Anja, Klapper, Wolfram, Greene, Franziska, Salzburg, Janina, Damm-Welk, Christine, Zimmermann, Martin, Strauch, Konstantin, Ludwig, Wolf-Dieter, Schrappe, Martin, and Reiter, Alfred

Subjects
*PEDIATRICS, *LYMPHOBLASTIC leukemia, *LYMPHOMAS, *HETEROZYGOSITY, *CHROMOSOMES, *PROGNOSIS
Abstract

Deletions on chromosome 6q are frequently reported in hematological malignancies. However, their biological or prognostic impact has not yet been clarified. This study analyzed loss of heterozygosity (LOH) at chromosome 6q and compared the LOH findings in pediatric precursor T lymphoblastic lymphoma (T-LBL) with the LOH findings in precursor-T lymphoblastic leukemia (T-ALL). For LOH analyses, a set of 25 microsatellite-markers on 6q14-q24 were examined. All patients were treated uniformly according to ALL-BFM-type treatment-strategy. A total of 1671 markers were successfully analyzed from 108 T-LBL patients. LOH was detected in 21 T-LBL patients. There was clear association between LOH at 6q and an increased risk of relapse. In comparison, 3109 markers were successfully analyzed from 127 T-ALL-patients. LOH was detected in 16 patients, but was not associated with increased relapse-rate. The localization of the common LOH regions identified for T-LBL and T-ALL samples did not overlap. Therefore patterns of LOH at 6q and the prognostic impact of LOH differ between T-ALL and T-LBL. These results hint at biologic differences between the two diseases. [ABSTRACT FROM AUTHOR]

Published
2008
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25. Varicella vaccination in a child with acute lymphoblastic leukaemia.

Author

Schrauder, André, Henke-Gendo, Cornelia, Seidemann, Kathrin, Sasse, Michael, Cario, Gunnar, Moericke, Anja, Schrappe, Martin, Heim, Albert, and Wessel, Armin

Subjects
*LYMPHOBLASTIC leukemia in children, *LEUKEMIA complications, *VACCINATION complications, *VARICELLA-zoster virus diseases, *RESPIRATORY distress syndrome, *VACCINE research, *DRUG side effects, *VACCINATION, *DISEASE risk factors, CANCER case studies
Abstract

The article presents a case study regarding the use of the varicella vaccine in a child with acute lymphoblastic leukemia (ALL). In 2003 a 4-year-old girl presented with generalized tonic-clonic seizures during reinduction treatment for ALL. She had been treated according to protocol with ALL-BFM 2000. The child died of progressive acute respiratory distress syndrome (ARDS) and multi-organ failure 10 days after treatment. The patient's mother recalled that her daughter received live attenuated varicella-zoster virus (VZV) vaccine at another hospital 32 days before the onset of symptoms. Experts say VZV vaccinations should not be given to children with ALL until they are in complete remission for at least 12 months.

Published
2007
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