22 results on '"Mark E. Cinque"'
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2. Biologically Augmented Quadriceps Tendon Autograft With Platelet-Rich Plasma for Anterior Cruciate Ligament Reconstruction
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Jorge Chahla, M.D., Ph.D., Mark E. Cinque, M.D., and Bert R. Mandelbaum, M.D., D.H.L., (hon.)
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Orthopedic surgery ,RD701-811 - Abstract
Anterior cruciate ligament (ACL) reconstruction is one of the most common procedures studied in the orthopaedic literature. In this regard, graft preparation is a key factor for successful outcomes. Although current methods to reconstruct the ACL are generally perceived to be successful, recent studies indicate that normal structure and function of the knee are fully restored in less than half of the patients. Therefore, biologically augmenting these scaffolds could provide a potential solution for improving healing times and biomechanical properties of the graft. The purpose of this Technical Note is to describe our preferred technique for an ACL graft preparation (quadriceps tendon) augmented with platelet-rich plasma.
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- 2018
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3. Open Repair of Quadriceps Tendon With Suture Anchors and Semitendinosus Tendon Allograft Augmentation
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Jorge Chahla, M.D., Ph.D., Nicholas N. DePhillipo, M.S., A.T.C., O.T.C., Mark E. Cinque, M.S., Nicholas I. Kennedy, M.D., George F. Lebus, M.D., Filippo Familiari, M.D., Gilbert Moatshe, M.D., and Robert F. LaPrade, M.D., Ph.D.
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Orthopedic surgery ,RD701-811 - Abstract
Quadriceps tendinopathy in an increasingly recognized diagnosis can lead to quadriceps tendon rupture, especially in the older population. It can be caused by repeated micro trauma or also predisposed by systemic diseases such as diabetes mellitus and connective tissue disorders that can in turn lead to extensor mechanism deficits. Although a trial of conservative treatment is advocated, operative treatment should be performed in cases of persistent pain, extension deficit, or complete rupture of the tendon. The purpose of this Technical Note is to describe in detail a procedure for open repair of a quadriceps tendon, with significant degeneration due to quadriceps tendinopathy, using suture anchors and semitendinosus tendon allograft augmentation.
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- 2017
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4. Meniscal Repair With Fibrin Clot Augmentation
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Jorge Chahla, M.D., Ph.D., Nicholas I. Kennedy, M.D., Andrew G. Geeslin, M.D., Gilbert Moatshe, M.D., Mark E. Cinque, M.S., Nicholas N. DePhillipo, M.S., A.T.C., O.T.C., and Robert F. LaPrade, M.D., Ph.D.
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Orthopedic surgery ,RD701-811 - Abstract
Meniscal injuries and meniscal loss are associated with changes in knee kinematics and loading, ultimately leading to poor functional outcomes and increased risk of progression to osteoarthritis. Biomechanical studies have shown restored knee function, and clinical studies have reported improved outcomes and decreased risk of osteoarthritis after meniscal repair. This has led orthopaedic surgeons to try and save the meniscus by repair whenever possible, as shown by increasing incidence of meniscal repair surgeries. Historically, meniscal lesions, particularly those greater in size and located in the white-white region of the meniscus, have been shown to have poor healing. In recent years, there has been an increasing interest in the use of biologic agents to help stimulate and expedite healing in traditionally more avascular tissue. Preliminary results for biologic therapeutic agents, such as platelet rich plasma and bone marrow aspirate concentrate, have been encouraging. However, these options are more demanding in regard to time, financial burden, resources, and regulations than some more classic agents such as fibrin clots. Fibrin clot is readily available, easy to use, affordable, and minimally invasive. This Technical Note describes a step-by-step and reproducible technique for harvesting, preparation, and using a fibrin clot to augment healing of meniscal repairs.
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- 2017
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5. Hamstring Graft Preparation Techniques for Anterior Cruciate Ligament Reconstruction
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Gustavo Vinagre, M.D., Nicholas I. Kennedy, M.D., Jorge Chahla, M.D., Ph.D., Mark E. Cinque, M.S., Zaamin B. Hussain, B.A., Morten L. Olesen, M.D., and Robert F. LaPrade, M.D., Ph.D.
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Orthopedic surgery ,RD701-811 - Abstract
Anterior cruciate ligament reconstruction is one of the most commonly performed procedures in orthopaedics, with more than 125,000 performed in the United States per year. There are several reconstruction graft choices that can be used to reconstruct the native anterior cruciate ligament, with autograft hamstring tendons being one of the most commonly used. Preparation of a hamstring autograft varies depending on patient characteristics and physician preference. The purpose of this Technical Note is to describe in detail different variants of hamstring graft preparation techniques that are commonly used in practice.
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- 2017
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6. Comprehensive Clinical Evaluation of Femoroacetabular Impingement: Part 1, Physical Examination
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Salvatore Frangiamore, M.D., M.S., Sandeep Mannava, M.D., Ph.D., Andrew G. Geeslin, M.D., Jorge Chahla, M.D., Ph.D., Mark E. Cinque, M.S., and Marc J. Philippon, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
A thorough evaluation of the hip must include a comprehensive medical and surgical history focused on the hip joint, surrounding soft tissues, and the associated structures of the spine, pelvis, and lower extremities. These details can guide the physical examination and provide insight into the cause of the patient's chief complaints. A proper examination includes physical examination while the patient is in the upright, supine, prone, and lateral position, as well as an evaluation of gait. Guided by a thorough history, the physical examination enables the surgeon to distinguish between intra-articular and extra-articular contributors to hip pain, selection of appropriate imaging modalities, and ultimately supports medical decision making.
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- 2017
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7. Osteochondral Allograft Transplants for Large Trochlear Defects
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Mark E. Cinque, B.S., M.S., Nicholas I. Kennedy, M.D., Gilbert Moatshe, M.D., Gustavo Vinagre, M.D., Jorge Chahla, M.D., Ph.D., Zaamin B. Hussain, B.A., and Robert F. LaPrade, M.D., Ph.D.
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Orthopedic surgery ,RD701-811 - Abstract
Focal articular cartilage injuries in the knee are common and can cause severe morbidity and reduced function. The articular cartilage is avascular and has limited ability to heal, and hence, patients with cartilage injuries have increased risk of progressing to osteoarthritis. Most of the cartilage injuries are located on the femoral condyles. Engaging focal cartilage injuries involving the trochlea are challenging because of the morbidity caused by these injuries and the limited treatment options. Osteochondral allograft transplantation is emerging as a promising treatment for full-thickness articular cartilage defects. Recent studies have reported high success rates with the use of osteochondral allografts. This article reports our technique of osteochondral allograft transplantation for the treatment of a focal full-thickness defect of the trochlea.
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- 2017
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8. Comprehensive Clinical Evaluation of Femoroacetabular Impingement: Part 2, Plain Radiography
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Sandeep Mannava, M.D., Ph.D., Andrew G. Geeslin, M.D., Salvatore J. Frangiamore, M.D., M.S., Mark E. Cinque, M.S., Matthew G. Geeslin, M.D., Jorge Chahla, M.D., Ph.D., and Marc J. Philippon, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
The use of hip arthroscopy to treat various forms of hip pathology continues to grow. As part of a standard evaluation for eligibility for hip arthroscopy, we routinely obtain standard radiographs to assess the hip joint. These include orthogonal projections of the acetabulum and proximal femur, which can be obtained with a standing false profile, supine anteroposterior pelvis, and a lateral view of the proximal femur (either Dunn 45° or 90°, frog-leg lateral, or cross-table lateral). A comprehensive analysis of the radiographs is of utmost importance in order to indicate a patient for hip arthroscopy, for preoperative planning, and to determine prognosis. The purpose of this Technical Note is to provide a comprehensive guide of how our group performs qualitative and quantitative analysis of hip radiographs in a potential candidate for hip arthroscopy.
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- 2017
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9. Reverse Total Shoulder Arthroplasty With Humeral Head Autograft Fixed Onto Glenoid for Treatment of Severe Glenoid Retroversion
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Zaamin B. Hussain, B.A., Jonathan A. Godin, M.D., M.B.A., George Sanchez, B.S., Nicholas I. Kennedy, M.D., Mark E. Cinque, M.S., Márcio B. Ferrari, M.D., and CAPTM.D., M.C., U.S.N.R. Matthew T. Provencher, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Advanced glenohumeral osteoarthritis can transform glenoid morphology and, in some cases, is found in association with severe glenoid retroversion. The associated glenoid retroversion leads to difficulty in fixation of the glenoid component in reverse total shoulder arthroplasty. In the context of extreme glenoid wear, structural grafts can be used to restore glenoid volume and version in order for the glenoid component of the reverse total shoulder arthroplasty to be more easily implanted. Nevertheless, literature regarding structural grafts remains limited, with optimal graft choice and technique still controversial at best. This article details our technique for humeral head autograft transplantation before reverse total shoulder arthroplasty in the context of extreme glenoid retroversion with advanced osteoarthritis.
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- 2017
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10. Multicompartmental Osteochondral Allografts of Knee and Concomitant High Tibial Osteotomy
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Jonathan A. Godin, M.D., M.B.A., Zaamin B. Hussain, B.A., Anthony Sanchez, B.S., George Sanchez, B.S., Márcio B. Ferrari, M.D., Mark E. Cinque, M.S., Nicholas I. Kennedy, M.D., and CAPTM.D., M.C., U.S.N.R. Matthew T. Provencher, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Chondral lesions of the knee can occur secondary to limb malalignment. To address these interrelated problems, a high tibial osteotomy with concomitant osteochondral allograft transfer may be performed. It is important to address these chondral lesions as they often affect the young and active population and cause morbidity in an otherwise healthy population. Although numerous approaches for the treatment of chondral lesions have been described, long-term results demonstrating regeneration of hyaline cartilage have yet to be reported. Furthermore, larger, full-thickness cartilage defects, which can be caused by limb malalignment, have proven to be particularly challenging to treat. This Technical Note details our technique for multicompartmental osteochondral allograft transplantation with concomitant high tibial osteotomy in a patient with 2 focal cartilage lesions in the knee.
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- 2017
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11. Arthroscopic Anatomic Single-Bundle Anterior Cruciate Ligament Reconstruction Using Bone–Patellar Tendon–Bone Autograft: Pearls for an Accurate Reconstruction
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Jorge Chahla, M.D., Ph.D., Gilbert Moatshe, M.D., Mark E. Cinque, M.S., Jonathan Godin, M.D., M.B.A., Sandeep Mannava, M.D., Ph.D., and Robert F. LaPrade, M.D., Ph.D.
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Orthopedic surgery ,RD701-811 - Abstract
An anterior cruciate ligament (ACL) tear is one of the most common orthopaedic injuries. Optimal results are not always achieved after surgical reconstruction after a surgical technical error, namely, tunnel malposition. Understanding of the anatomy is vital, and several anatomic landmarks can be used to aid in an optimal reconstruction technique. The purpose of this Technical Note is to describe our preferred technique for an arthroscopic single-bundle anteromedial ACL reconstruction, using a bone–patellar tendon–bone autograft fixed with interference screws.
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- 2017
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12. Osteochondral Allograft Transplantation for Treatment of Medial Femoral Condyle Defect
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Jonathan A. Godin, M.D., M.B.A., George Sanchez, B.S., Mark E. Cinque, B.S., M.S., Jorge Chahla, M.D., Ph.D., Nicholas I. Kennedy, M.D., and CAPTM.D., M.C., U.S.N.R. Matthew T. Provencher, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Chondral lesions of the knee can affect the young, active population, thereby causing severe morbidity and a large economic burden. Although numerous approaches have been described in the literature, restoration of hyaline cartilage has yet to be shown. Specifically, larger, full-thickness cartilage defects remain a challenge. This Technical Note details our technique for biologic unicompartmental osteochondral allograft transplantation for the treatment of large femoral condyle articular cartilage defects.
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- 2017
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13. Arthroscopic Inside-Out Repair of a Meniscus Bucket-Handle Tear Augmented With Bone Marrow Aspirate Concentrate
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Kyle J. Muckenhirn, B.A., Bradley M. Kruckeberg, B.A., Mark E. Cinque, B.S., Jorge Chahla, M.D., Ph.D., Nicholas N. DePhillipo, M.S., A.T.C., O.T.C., Jonathan A. Godin, M.D., M.B.A., and Robert F. LaPrade, M.D., Ph.D.
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Orthopedic surgery ,RD701-811 - Abstract
Bucket-handle tears of the meniscus comprise nearly 10% of all meniscus tears and commonly affect the young male population. Displacement of the free segment can lead to significant pain and disability, necessitating reduction and surgical treatment. General contraindications include malalignment, severe arthritis, significant comorbidities, or chronic asymptomatic tears, but otherwise repair should almost always be performed. Options for surgical treatment include partial meniscectomy and arthroscopic repair using an all-inside, outside-in, or inside-out technique. The purpose of this Technical Note is to detail our arthroscopic inside-out repair technique augmented with bone marrow aspirate concentrate.
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- 2017
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14. Inside-Out Repair of Meniscal Ramp Lesions
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Nicholas N. DePhillipo, M.S., A.T.C., O.T.C., Mark E. Cinque, M.S., Nicholas I. Kennedy, M.D., Jorge Chahla, M.D., Ph.D., Andrew G. Geeslin, M.D., Gilbert Moatshe, M.D., Lars Engebretsen, M.D., Ph.D., and Robert F. LaPrade, M.D., Ph.D.
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Orthopedic surgery ,RD701-811 - Abstract
Meniscal ramp lesions have been reported to be present in 9% to 17% of patients undergoing anterior cruciate ligament reconstruction. Detection at the time of arthroscopy can be accomplished based upon clinical suspicion and careful evaluation without the use of an accessory posteromedial portal. Options for surgical treatment include arthroscopic repair using an all-inside or inside-out technique. The purpose of this Technical Note is to detail our arthroscopic inside-out repair technique for meniscal ramp lesions.
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- 2017
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15. Subpectoral Biceps Tenodesis: Interference Screw and Cortical Button Fixation
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Nicholas I. Kennedy, M.D., Jonathan A. Godin, M.D., Marcio B. Ferrari, M.D., George Sanchez, B.S., Mark E. Cinque, M.S., Zaamin B. Hussain, B.A., and CAPTM.D., M.C., U.S.N.R. Matthew T. Provencher, B.A.
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Orthopedic surgery ,RD701-811 - Abstract
Bicep tendon pathology often arises from chronic overuse injuries, acute trauma, or degenerative changes in the glenohumeral joint. These injuries can cause significant shoulder pain, and can greatly limit range of motion and, in turn, activities of daily living. The diagnosis of biceps pathologies can be challenging, because patients often present with nonspecific symptoms. Some bicep tendon pathologies may be treated nonoperatively; however, biceps tendon subluxation and the presence of rotator cuff or SLAP lesions require surgical management. One of the options for the treatment of bicep tendon pathology includes miniopen subpectoral biceps tenodesis. The purpose of this Technical Note is to describe in detail our preferred operative technique for miniopen subpectoral biceps tenodesis with 2 different fixation methods.
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- 2017
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16. Tibial Allograft Transfer for Medial Tibial Plateau Resurfacing
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Jonathan A. Godin, M.D., M.B.A., Salvatore Frangiamore, M.D., M.S., Jorge Chahla, M.D., Mark E. Cinque, M.D., Nicholas N. DePhillipo, M.S., A.T.C., O.T.C., and Robert F. LaPrade, M.D., Ph.D.
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Orthopedic surgery ,RD701-811 - Abstract
A large cartilage lesion of the tibial plateau with a deficient meniscus in a young patient is a challenging pathology for the orthopaedic surgeon due to the limited options available. While hemiarthroplasty procedures can be an option, the risk of revision in a young patient is high, and therefore a reconstructive procedure is advocated. The purpose of this Technical Note is to describe our technique for tibial plateau resurfacing, including the preparation and implantation of a medial tibial plateau and medial meniscal allograft, in a patient with a post-traumatic KD-4 knee dislocation with a medial tibial plateau rim fracture, medial meniscus deficiency, and medial tibiofemoral joint subluxation.
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- 2017
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17. Platelet-Rich Plasma Augmentation for Hip Arthroscopy
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Sandeep Mannava, M.D., Ph.D., Jorge Chahla, M.D., Ph.D., Andrew G. Geeslin, M.D., Mark E. Cinque, B.S., Kaitlyn E. Whitney, B.S., Thos A. Evans, M.D., Salvatore J. Frangiamore, M.D., M.S., George LeBus, M.D., Jonathan Godin, M.D., M.B.A., Robert F. LaPrade, M.D., Ph.D., and Marc J. Philippon, M.D.
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Orthopedic surgery ,RD701-811 - Abstract
Biological augmentation and therapeutics are being increasingly used in musculoskeletal and orthopaedic care. Platelet-rich plasma (PRP) is produced from centrifugation of peripheral blood, a process that concentrates platelets within autologous plasma. The process of PRP preparation is fundamental in controlling the contents, and it influences its therapeutic potential. Platelets contain alpha granules that store and release a variety of growth factors and other proteins that may augment the healing environment; PRP also has the added benefit of promoting postsurgical hemostasis. The purpose of this report was to detail our institutional preparation protocol and method of administration of PRP during hip arthroscopy.
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- 2017
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18. Bone Marrow Aspirate Concentrate Harvesting and Processing Technique
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Jorge Chahla, M.D., Sandeep Mannava, M.D., Ph.D., Mark E. Cinque, B.S., Andrew G. Geeslin, M.D., David Codina, M.D., and Robert F. LaPrade, M.D., Ph.D.
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Orthopedic surgery ,RD701-811 - Abstract
Bone marrow obtained by iliac crest aspiration is a common source for harvesting mesenchymal stem cells, other progenitor cells, and associated cytokine/growth factors. Recent studies have reported good to excellent outcomes with the use of bone marrow aspirate concentrate (BMAC) for pain relief in the treatment of focal chondral lesions and osteoarthritis of the knee. However, the harvesting and processing technique are crucial to achieve satisfactory results. Several studies have examined outcomes after BMAC injection, with encouraging results, but there is a lack of consensus in terms of the frequency of injection, the amount of BMAC that is injected, and the timing of BMAC injections. The purpose of this Technical Note was to describe a standardized bone marrow aspiration harvesting technique and processing method.
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- 2017
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19. Bone marrow aspirate concentrate for the treatment of osteochondral lesions of the talus: a systematic review of outcomes
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Jorge Chahla, Mark E. Cinque, Jason M. Schon, Daniel J. Liechti, Lauren M. Matheny, Robert F. LaPrade, and Thomas O. Clanton
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Bone marrow aspirate concentrate ,Talar osteochondral lesion ,BMAC treatment of osteochondral defects ,Orthopedic surgery ,RD701-811 - Abstract
Abstract Background The goal of this perform a systematic review on the outcomes of bone marrow aspirate concentrate (BMAC) for the treatment of chondral defects and osteoarthritis (OA) of the talus. Results The systematic search performed identified 47 studies after duplicates were removed. After inclusion criteria were applied four studies were considered for insightful analysis for the treatment of focal chondral defects in the foot and ankle with the use of BMAC. Three studies were retrospective and one study was prospective in nature. One study was a comparative cohort study and three studies were case series. Conclusions This review denotes that there exists an overwhelming paucity of long‐term data and high‐level evidence supporting BMAC for the treatment of chondral defects. Nonetheless, the evidence available showed varying degrees of beneficial results of BMAC for the treatment of ankle cartilage defects. The limited literature presented in this review demonstrates the need for more advanced, comparative studies to further investigate the efficacy, safety and techniques for BMAC in the treatment of OLTs. The authors recommend that BMAC therapy should be performed with careful consideration until the application and target population for this treatment are established.
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- 2016
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20. Erratum to: Bone marrow aspirate concentrate for the treatment of osteochondral lesions of the talus: a systematic review of outcomes
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Jorge Chahla, Mark E. Cinque, Jason M. Schon, Daniel J. Liechti, Lauren M. Matheny, Robert F. LaPrade, and Thomas O. Clanton
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Orthopedic surgery ,RD701-811 - Published
- 2016
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21. Multiligament Knee Injuries in Older Adolescents: A 2-Year Minimum Follow-up Study
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Robert F. LaPrade, Gilbert Moatshe, Jonas Pogorzelski, Jonathan A. Godin, Mark E. Cinque, and Jorge Chahla
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030222 orthopedics ,medicine.medical_specialty ,Functional impairment ,business.industry ,Follow up studies ,Knee reconstruction ,030229 sport sciences ,Evidence-based medicine ,outcomes ,Adolescent population ,multiligament knee injuries ,03 medical and health sciences ,0302 clinical medicine ,Patient age ,adolescent ,Physical therapy ,medicine ,Orthopedics and Sports Medicine ,Knee injuries ,business - Abstract
Background: Multiligament knee injuries cause significant functional impairment. Adults undergoing anatomic reconstruction of multiligament knee injuries have excellent outcomes postoperatively. However, less is known about the outcomes in adolescent patients following multiligament reconstruction. Purpose/Hypothesis: We aimed to assess patient outcomes and failure rates following unstaged multiligament reconstruction in an adolescent population at a minimum 2-year follow-up. We hypothesized that outcomes of multiligament reconstruction in these patients would be comparable to previously reported outcomes in the adult population. Study Design: Case series; Level of evidence, 4. Methods: The study included patients who had undergone multiligament knee reconstruction at 19 years of age or younger and had at least 2 years of follow-up. All procedures were performed by the same surgeon. Exclusion criteria included patient age 14 years or younger at the time of surgery, open physes, prior ipsilateral meniscal or knee ligament surgery, or a tibial plateau fracture at the time of injury. Multiligament reconstruction was defined as a reconstruction of at least 1 cruciate ligament and at least 1 component of the posterolateral corner or the medial knee. Patients were evaluated according to Lysholm score, Tegner score, Short Form–12 physical component summary (SF-12 PCS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, and postoperative patient satisfaction. Results: Twenty patients (mean age, 17.7 years; mean follow-up, 37.1 months) were included in this study. No patient required additional ligament surgery after the index surgery because of graft failure. The median preoperative Lysholm score was 49.5 (range, 18-90), and the median postoperative Lysholm score was 86 (range, 44-100) (P < .001). The median preoperative Tegner activity score was 2 (range, 0-9), and the median postoperative Tegner activity score was 6 (range, 2-10) (P = .012). The median SF-12 PCS improved from 40.5 preoperatively to a median of 56.1 postoperatively (P < .001). WOMAC total score improved from a median of 26.5 preoperatively to a median of 2 postoperatively (P < .001). Median postoperative patient satisfaction was 10 (range, 5-10). Conclusion: Single-stage multiligament knee reconstruction is a reliable procedure that improves knee function at 2-year follow-up in adolescent patients. Patient satisfaction was excellent, but longer follow-up in a larger series of patients is required to determine the long-term benefits of multiligament reconstruction in this patient population.
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- 2017
22. Biological treatment of the knee with platelet-rich plasma or bone marrow aspirate concentrates: A review of the current status
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Gilbert Moatshe, Elizabeth R Morris, Mark E Cinque, Cecilia Pascual-Garrido, Jorge Chahla, Lars Engebretsen, and Robert F Laprade
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Orthopedic surgery ,RD701-811 - Abstract
ABSTRACT — Knee pathologies including focal cartilage injuries, osteoarthritis (OA), and ligament injuries are common. The poor regeneration and healing potential of cartilage has led to the search for other treatment modalities with improved healing capacity. Furthermore, with an increasing elderly population that desires to remain active, the burden of knee pathologies is expected to increase. Increased sports participation and the desire to return to activities faster is also demanding more effective and minimally invasive treatment options. Thus, the use of biologic agents in the treatment of knee pathologies has emerged as a potential option. Despite the increasing use of biologic agents for knee pathology, there are conflicting results on the efficacy of these products. Furthermore, strong data supporting the optimal preparation methods and composition for widely used biologic agents, such as platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC), largely remain absent from the literature. This review presents the literature on the most commonly employed biologic agents for the different knee pathologies.
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- 2017
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