46 results on '"Lajoie, Bryan R."'
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2. Sequencing by avidity enables high accuracy with low reagent consumption
3. An automated 13.5 hour system for scalable diagnosis and acute management guidance for genetic diseases
4. Avidity sequencing of whole genomes from retinal degeneration pedigrees identifies causal variants.
5. Higher-Order Organization Principles of Pre-translational mRNPs
6. Heterochromatin drives compartmentalization of inverted and conventional nuclei
7. ExpansionHunter Denovo: a computational method for locating known and novel repeat expansions in short-read sequencing data
8. Integrative detection and analysis of structural variation in cancer genomes
9. RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells
10. Activation of proto-oncogenes by disruption of chromosome neighborhoods
11. Invariant TAD Boundaries Constrain Cell-Type-Specific Looping Interactions between Promoters and Distal Elements around the CFTR Locus
12. Highly structured homolog pairing reflects functional organization of the Drosophila genome
13. The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos
14. Measuring the reproducibility and quality of Hi-C data
15. The Conformation of Yeast Chromosome III Is Mating Type Dependent and Controlled by the Recombination Enhancer
16. High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila
17. X-linked hypomyelination with spondylometaphyseal dysplasia (H-SMD) associated with mutations in AIFM1
18. The Hitchhiker’s guide to Hi-C analysis: Practical guidelines
19. Extensive Rewiring and Complex Evolutionary Dynamics in a C. elegans Multiparameter Transcription Factor Network
20. Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment
21. Organization of the Mitotic Chromosome
22. MORC Family ATPases Required for Heterochromatin Condensation and Gene Silencing
23. Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations
24. Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
25. CANCER: Activation of proto-oncogenes by disruption of chromosome neighborhoods
26. Condensin-driven remodelling of X chromosome topology during dosage compensation
27. HiTC: exploration of high-throughput ‘C’ experiments
28. An integrated encyclopedia of DNA elements in the human genome
29. The long-range interaction landscape of gene promoters
30. Spatial partitioning of the regulatory landscape of the X-inactivation centre
31. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
32. An encyclopedia of mouse DNA elements (Mouse ENCODE)
33. Genome sequencing in persistently unsolved white matter disorders.
34. ExpansionHunter: a sequence-graph-based tool to analyze variation in short tandem repeat regions.
35. Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma.
36. Structural organization of the inactive X chromosome in the mouse.
37. HiC-Pro: an optimized and flexible pipeline for Hi-C data processing.
38. Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells.
39. Iterative correction of Hi-C data reveals hallmarks of chromosome organization.
40. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression.
41. The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules.
42. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma
43. Iterative Correction of Hi-C Data Reveals Hallmarks of Chromosome Organization
44. Evidence for Transcript Networks Composed of Chimeric RNAs in Human Cells
45. Condensin promotes the juxtaposition of DNA flanking its loading site in Bacillus subtilis.
46. Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments.
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